Regulation of Age-related Decline by Transcription Factors and Their Crosstalk with the Epigenome

por Zhou, Xin, Sen, Ilke, Lin, Xin-Xuan, Riedel, Christian G.
Publicado 2018

Soluble Klotho protects against glomerular injury through regulation of ER stress response

por Charrin, Emmanuelle, Dabaghie, Dina, Sen, Ilke, Unnersjö-Jess, David, Möller-Hackbarth, Katja, Burmakin, Mikhail, Mencke, Rik, Zambrano, Sonia, Patrakka, Jaakko, Olauson, Hannes
Publicado 2023

Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging

por Janssens, Georges E., Lin, Xin-Xuan, Millan-Ariño, Lluís, Kavšek, Alan, Sen, Ilke, Seinstra, Renée I., Stroustrup, Nicholas, Nollen, Ellen A.A., Riedel, Christian G.
Publicado 2019

DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity

por Lin, Xin-Xuan, Sen, Ilke, Janssens, Georges E., Zhou, Xin, Fonslow, Bryan R., Edgar, Daniel, Stroustrup, Nicholas, Swoboda, Peter, Yates, John R., Ruvkun, Gary, Riedel, Christian G.
Publicado 2018

DAF-16/FOXO requires Protein Phosphatase 4 to initiate transcription of stress resistance and longevity promoting genes

por Sen, Ilke, Zhou, Xin, Chernobrovkin, Alexey, Puerta-Cavanzo, Nataly, Kanno, Takaharu, Salignon, Jérôme, Stoehr, Andrea, Lin, Xin-Xuan, Baskaner, Bora, Brandenburg, Simone, Björkegren, Camilla, Zubarev, Roman A., Riedel, Christian G.
Publicado 2020

An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation

por Casteels, Tamara, Zhang, Yufeng, Frogne, Thomas, Sturtzel, Caterina, Lardeau, Charles-Hugues, Sen, Ilke, Liu, Xiaocheng, Hong, Shangyu, Pauler, Florian M., Penz, Thomas, Brandstetter, Marlene, Barbieux, Charlotte, Berishvili, Ekaterine, Heuser, Thomas, Bock, Christoph, Riedel, Christian G., Meyer, Dirk, Distel, Martin, Hecksher-Sørensen, Jacob, Li, Jin, Kubicek, Stefan
Publicado 2021