Culture shock: microglial heterogeneity, activation, and disrupted single-cell microglial networks in vitro

por Cadiz, Mika P., Jensen, Tanner D., Sens, Jonathon P., Zhu, Kuixi, Song, Won-Min, Zhang, Bin, Ebbert, Mark, Chang, Rui, Fryer, John D.
Publicado 2022

Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau

por Kang, Silvia S., Ebbert, Mark T.W., Baker, Kelsey E., Cook, Casey, Wang, Xuewei, Sens, Jonathon P., Kocher, Jeanne-Pierre, Petrucelli, Leonard, Fryer, John D.
Publicado 2018

Astrocyte-derived clusterin suppresses amyloid formation in vivo

por Wojtas, Aleksandra M., Sens, Jonathon P., Kang, Silvia S., Baker, Kelsey E., Berry, Taylor J., Kurti, Aishe, Daughrity, Lillian, Jansen-West, Karen R., Dickson, Dennis W., Petrucelli, Leonard, Bu, Guojun, Liu, Chia-Chen, Fryer, John D.
Publicado 2020

Long-read sequencing across the C9orf72 ‘GGGGCC’ repeat expansion: implications for clinical use and genetic discovery efforts in human disease

por Ebbert, Mark T. W., Farrugia, Stefan L., Sens, Jonathon P., Jansen-West, Karen, Gendron, Tania F., Prudencio, Mercedes, McLaughlin, Ian J., Bowman, Brett, Seetin, Matthew, DeJesus-Hernandez, Mariely, Jackson, Jazmyne, Brown, Patricia H., Dickson, Dennis W., van Blitterswijk, Marka, Rademakers, Rosa, Petrucelli, Leonard, Fryer, John D.
Publicado 2018

Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

por Ebbert, Mark T. W., Jensen, Tanner D., Jansen-West, Karen, Sens, Jonathon P., Reddy, Joseph S., Ridge, Perry G., Kauwe, John S. K., Belzil, Veronique, Pregent, Luc, Carrasquillo, Minerva M., Keene, Dirk, Larson, Eric, Crane, Paul, Asmann, Yan W., Ertekin-Taner, Nilufer, Younkin, Steven G., Ross, Owen A., Rademakers, Rosa, Petrucelli, Leonard, Fryer, John D.
Publicado 2019

Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation

por Wojtas, Aleksandra M., Carlomagno, Yari, Sens, Jonathon P., Kang, Silvia S., Jensen, Tanner D., Kurti, Aishe, Baker, Kelsey E., Berry, Taylor J., Phillips, Virginia R., Castanedes, Monica Casey, Awan, Ayesha, DeTure, Michael, De Castro, Cristhoper H. Fernandez, Librero, Ariston L., Yue, Mei, Daughrity, Lillian, Jansen-West, Karen R., Cook, Casey N., Dickson, Dennis W., Petrucelli, Leonard, Fryer, John D.
Publicado 2020

K(ATP) channels are necessary for glucose-dependent increases in amyloid-β and Alzheimer’s disease–related pathology

por Grizzanti, John, Moritz, William R., Pait, Morgan C., Stanley, Molly, Kaye, Sarah D., Carroll, Caitlin M., Constantino, Nicholas J., Deitelzweig, Lily J., Snipes, James A., Kellar, Derek, Caesar, Emily E., Pettit-Mee, Ryan J., Day, Stephen M., Sens, Jonathon P., Nicol, Noelle I., Dhillon, Jasmeen, Remedi, Maria S., Kiraly, Drew D., Karch, Celeste M., Nichols, Colin G., Holtzman, David M., Macauley, Shannon L.
Publicado 2023