Uncoupling Oncogene-Induced Senescence (OIS) and DNA Damage Response (DDR) triggered by DNA hyper-replication: lessons from primary mouse embryo astrocytes (MEA)

por Seoane, Marcos, Costoya, José A., Arce, Víctor M.
Publicado 2017

The Mitochondrial Genome Is a “Genetic Sanctuary” during the Oncogenic Process

por Seoane, Marcos, Mosquera-Miguel, Ana, Gonzalez, Teresa, Fraga, Maximo, Salas, Antonio, Costoya, Jose A.
Publicado 2011

A New Opportunity for “Old” Molecules: Targeting PARP1 Activity through a Non-Enzymatic Mechanism

por Iglesias, Pablo, Seoane, Marcos, Golán-Cancela, Irene, Fraga, Máximo, Arce, Victor M., Costoya, Jose A.
Publicado 2023

Retinoblastoma Loss Modulates DNA Damage Response Favoring Tumor Progression

por Seoane, Marcos, Iglesias, Pablo, Gonzalez, Teresa, Dominguez, Fernando, Fraga, Maximo, Aliste, Carlos, Forteza, Jeronimo, Costoya, Jose A.
Publicado 2008

PARP1 Deficiency Reduces Tumour Growth by Decreasing E2F1 Hyperactivation: A Novel Mechanism in the Treatment of Cancer

por Iglesias, Pablo, Seoane, Marcos, Golán, Irene, Castro-Piedras, Isabel, Fraga, Máximo, Arce, Víctor M., Costoya, Jose A.
Publicado 2020

Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair

por Seoane, Marcos, Buhs, Sophia, Iglesias, Pablo, Strauss, Julia, Puller, Ann-Christin, Müller, Jürgen, Gerull, Helwe, Feldhaus, Susanne, Alawi, Malik, Brandner, Johanna M., Eggert, Dennis, Du, Jinyan, Thomale, Jürgen, Wild, Peter J., Zimmermann, Martin, Sternsdorf, Thomas, Schumacher, Udo, Nollau, Peter, Fisher, David E., Horstmann, Martin A.
Publicado 2019