Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy

por Fan, Xiaozhou, Quezada, Sergio A., Sepulveda, Manuel A., Sharma, Padmanee, Allison, James P.
Publicado 2014

Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody

por Jarantow, Stephen W., Bushey, Barbara S., Pardinas, Jose R., Boakye, Ken, Lacy, Eilyn R., Sanders, Renouard, Sepulveda, Manuel A., Moores, Sheri L., Chiu, Mark L.
Publicado 2015

Anti-tumor activity of a T-helper 1 multiantigen vaccine in a murine model of prostate cancer

por Cecil, Denise L., Curtis, Benjamin, Gad, Ekram, Gormley, Michael, Timms, Andrew E., Corulli, Lauren, Bos, Rinke, Damle, Rajendra N., Sepulveda, Manuel A., Disis, Mary L.
Publicado 2022

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma

por Simpson, Tyler R., Li, Fubin, Montalvo-Ortiz, Welby, Sepulveda, Manuel A., Bergerhoff, Katharina, Arce, Frederick, Roddie, Claire, Henry, Jake Y., Yagita, Hideo, Wolchok, Jedd D., Peggs, Karl S., Ravetch, Jeffrey V., Allison, James P., Quezada, Sergio A.
Publicado 2013

Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice

por Veglia, Filippo, Hashimoto, Ayumi, Dweep, Harsh, Sanseviero, Emilio, De Leo, Alessandra, Tcyganov, Evgenii, Kossenkov, Andrew, Mulligan, Charles, Nam, Brian, Masters, Gregory, Patel, Jaymala, Bhargava, Vipul, Wilkinson, Patrick, Smirnov, Denis, Sepulveda, Manuel A., Singhal, Sunil, Eruslanov, Evgeniy B., Cristescu, Razvan, Loboda, Andrey, Nefedova, Yulia, Gabrilovich, Dmitry I.
Publicado 2021