Putting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?

por Elkholi, Rana, Renault, Thibaud T, Serasinghe, Madhavika N, Chipuk, Jerry E
Publicado 2014

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance

por Serasinghe, Madhavika N., Missert, Derek J., Asciolla, James J., Wieder, Shira Y., Podgrabinska, Simona, Izadmehr, Sudeh, Belbin, Gillian, Skobe, Mihaela, Chipuk, Jerry E.
Publicado 2014

Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma

por Wieder, Shira Y., Serasinghe, Madhavika N., Sung, Julie C., Choi, Daniel C., Birge, Miriam B., Yao, Jonathan L., Bernstein, Emily, Celebi, Julide T., Chipuk, Jerry E.
Publicado 2015

Repeated hypoglycemia remodels neural inputs and disrupts mitochondrial function to blunt glucose-inhibited GHRH neuron responsiveness

por Bayne, Mitchell, Alvarsson, Alexandra, Devarakonda, Kavya, Li, Rosemary, Jimenez-Gonzalez, Maria, Garibay, Darline, Conner, Kaetlyn, Varghese, Merina, Serasinghe, Madhavika N., Chipuk, Jerry E., Hof, Patrick R., Stanley, Sarah A.
Publicado 2020

Dual suppression of inner and outer mitochondrial membrane functions augments apoptotic responses to oncogenic MAPK inhibition

por Serasinghe, Madhavika N., Gelles, Jesse D., Li, Kent, Zhao, Lauren, Abbate, Franco, Syku, Marie, Mohammed, Jarvier N., Badal, Brateil, Rangel, Cuahutlehuanitzin A., Hoehn, Kyle L., Celebi, Julide Tok, Chipuk, Jerry Edward
Publicado 2018

Late-onset megaconial myopathy in mice lacking group I Paks

por Joseph, Giselle A., Hung, Margaret, Goel, Aviva J., Hong, Mingi, Rieder, Marysia-Kolbe, Beckmann, Noam D., Serasinghe, Madhavika N., Chipuk, Jerry E., Devarakonda, Parvathi M., Goldhamer, David J., Aldana-Hernandez, Paulina, Curtis, Jonathan, Jacobs, René L., Krauss, Robert S.
Publicado 2019