TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form

por Thiyagarajan, Dhivya, Rekvig, Ole Petter, Seredkina, Natalya
Publicado 2015

Anti-dsDNA Antibodies Promote Initiation, and Acquired Loss of Renal Dnase1 Promotes Progression of Lupus Nephritis in Autoimmune (NZBxNZW)F1 Mice

por Fenton, Kristin, Fismen, Silje, Hedberg, Annica, Seredkina, Natalya, Fenton, Chris, Mortensen, Elin Synnøve, Rekvig, Ole Petter
Publicado 2009

Lupus nephritis progression in FcγRIIB(-/-)yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease

por Horvei, Kjersti Daae, Pedersen, Hege Lynum, Fismen, Silje, Thiyagarajan, Dhivya, Schneider, Andrea, Rekvig, Ole Petter, Winkler, Thomas H., Seredkina, Natalya
Publicado 2017

Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e

por Thiyagarajan, Dhivya, Fismen, Silje, Seredkina, Natalya, Jacobsen, Søren, Elung-Jensen, Thomas, Kamper, Anne-Lise, Fenton, Christopher Graham, Rekvig, Ole Petter, Mortensen, Elin Synnøve
Publicado 2012

IL-1β Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene

por Thiyagarajan, Dhivya, Pedersen, Hege L., Seredkina, Natalya, Horvei, Kjersti D., Arranz, Lorena, Sonneveld, Ramon, Nijenhuis, Tom, van der Vlag, Johan, Rekvig, Ole P.
Publicado 2018

Lupus nephritis: low urinary DNase I levels reflect loss of renal DNase I and may be utilized as a biomarker of disease progression

por Pedersen, Hege L, Horvei, Kjersti D, Thiyagarajan, Dhivya, Norby, Gudrun E, Seredkina, Natalya, Moroni, Gabriella, Eilertsen, Gro Ø, Holdaas, Hallvard, Strøm, Erik H, Bakland, Gunnstein, Meroni, Pier‐Luigi, Rekvig, Ole P
Publicado 2018