Nutraceutical Properties of Polyphenols against Liver Diseases

por Simón, Jorge, Casado-Andrés, María, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, Martínez-Chantar, María Luz
Publicado 2020

The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity

por Bailly, Aymeric P., Perrin, Aurelien, Serrano-Macia, Marina, Maghames, Chantal, Leidecker, Orsolya, Trauchessec, Helene, Martinez-Chantar, M.L., Gartner, Anton, Xirodimas, Dimitris P.
Publicado 2019

Ubiquitin-Like Post-Translational Modifications (Ubl-PTMs): Small Peptides with Huge Impact in Liver Fibrosis

por Lachiondo-Ortega, Sofia, Mercado-Gómez, Maria, Serrano-Maciá, Marina, Lopitz-Otsoa, Fernando, Salas-Villalobos, Tanya B, Varela-Rey, Marta, Delgado, Teresa C., Martínez-Chantar, María Luz
Publicado 2019

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

por Juárez‐Fernández, María, Goikoetxea‐Usandizaga, Naroa, Porras, David, García‐Mediavilla, María Victoria, Bravo, Miren, Serrano‐Maciá, Marina, Simón, Jorge, Delgado, Teresa C., Lachiondo‐Ortega, Sofía, Martínez‐Flórez, Susana, Lorenzo, Óscar, Rincón, Mercedes, Varela‐Rey, Marta, Abecia, Leticia, Rodríguez, Héctor, Anguita, Juan, Nistal, Esther, Martínez‐Chantar, María Luz, Sánchez‐Campos, Sonia
Publicado 2023

Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation

por Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Delacruz-Villar, Laura, Bilbao, Jon, Pagano, Martina, Mosca, Laura, Bizkarguenaga, Maider, Serrano-Macia, Marina, Azkargorta, Mikel, Iruarrizaga-Lejarreta, Marta, Sot, Jesús, Tsvirkun, Darya, van Liempd, Sebastiaan Martijn, Goni, Felix M, Alonso, Cristina, Martínez-Chantar, María Luz, Elortza, Felix, Hayardeny, Liat, Lu, Shelly C, Mato, José M
Publicado 2020

Neddylation tunes peripheral blood mononuclear cells immune response in COVID-19 patients

por Serrano-Maciá, Marina, Lachiondo-Ortega, Sofia, Iruzubieta, Paula, Goikoetxea-Usandizaga, Naroa, Bosch, Alexandre, Egia-Mendikute, Leire, Jiménez-Lasheras, Borja, Azkargorta, Mikel, Elortza, Félix, Martinez-Redondo, Diana, Castro, Begoña, Lozano, Juan J., Nogueiras, Ruben, Irure-Ventura, Juan, Crespo, Javier, Palazón, Asís, Fariñas, María Carmen, Delgado, Teresa C., López-Hoyos, Marcos, Martínez-Chantar, Maria L.
Publicado 2022

A flow cytometry-based neutralization assay for simultaneous evaluation of blocking antibodies against SARS-CoV-2 variants

por Egia-Mendikute, Leire, Bosch, Alexandre, Prieto-Fernández, Endika, Vila-Vecilla, Laura, Zanetti, Samanta Romina, Lee, So Young, Jiménez-Lasheras, Borja, García del Río, Ana, Antoñana-Vildosola, Asier, de Blas, Ander, Velasco-Beltrán, Paloma, Serrano-Maciá, Marina, Iruzubieta, Paula, Mehrpouyan, Majid, Goldberg, Edward M., Bornheimer, Scott J., Embade, Nieves, Martínez-Chantar, María L., López-Hoyos, Marcos, Mato, José M., Millet, Óscar, Palazón, Asís
Publicado 2022

Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism

por Gonzalez-Rellan, María J., Fernández, Uxía, Parracho, Tamara, Novoa, Eva, Fondevila, Marcos F., da Silva Lima, Natalia, Ramos, Lucía, Rodríguez, Amaia, Serrano-Maciá, Marina, Perez-Mejias, Gonzalo, Chantada-Vazquez, Pilar, Riobello, Cristina, Veyrat-Durebex, Christelle, Tovar, Sulay, Coppari, Roberto, Woodhoo, Ashwin, Schwaninger, Markus, Prevot, Vincent, Delgado, Teresa C., Lopez, Miguel, Diaz-Quintana, Antonio, Dieguez, Carlos, Guallar, Diana, Frühbeck, Gema, Diaz-Moreno, Irene, Bravo, Susana B., Martinez-Chantar, Maria L., Nogueiras, Ruben
Publicado 2023

The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes

por Mercado-Gómez, Maria, Prieto-Fernández, Endika, Goikoetxea-Usandizaga, Naroa, Vila-Vecilla, Laura, Azkargorta, Mikel, Bravo, Miren, Serrano-Maciá, Marina, Egia-Mendikute, Leire, Rodríguez-Agudo, Rubén, Lachiondo-Ortega, Sofia, Lee, So Young, Eguileor Giné, Alvaro, Gil-Pitarch, Clàudia, González-Recio, Irene, Simón, Jorge, Petrov, Petar, Jover, Ramiro, Martínez-Cruz, Luis Alfonso, Ereño-Orbea, June, Delgado, Teresa Cardoso, Elortza, Felix, Jiménez-Barbero, Jesús, Nogueiras, Ruben, Prevot, Vincent, Palazon, Asis, Martínez-Chantar, María L.
Publicado 2022

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

por Zubiete-Franco, Imanol, García-Rodríguez, Juan L., Lopitz-Otsoa, Fernando, Serrano-Macia, Marina, Simon, Jorge, Fernández-Tussy, Pablo, Barbier-Torres, Lucía, Fernández-Ramos, David, Gutiérrez-de-Juan, Virginia, López de Davalillo, Sergio, Carlevaris, Onintza, Beguiristain Gómez, Adolfo, Villa, Erica, Calvisi, Diego, Martín, César, Berra, Edurne, Aspichueta, Patricia, Beraza, Naiara, Varela-Rey, Marta, Ávila, Matias, Rodríguez, Manuel S., Mato, José M., Díaz-Moreno, Irene, Díaz-Quintana, Antonio, Delgado, Teresa C., Martínez-Chantar, María L.
Publicado 2018

miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease

por Fernández-Tussy, Pablo, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Simón, Jorge, Barbier-Torres, Lucía, Gomez-Santos, Beatriz, Nuñez-Garcia, Maitane, Azkargorta, Mikel, Gutiérrez-de Juan, Virginia, Serrano-Macia, Marina, Rodríguez-Agudo, Rubén, Iruzubieta, Paula, Anguita, Juan, Castro, Rui E., Champagne, Devin, Rincón, Mercedes, Elortza, Felix, Arslanow, Anita, Krawczyk, Marcin, Lammert, Frank, Kirchmeyer, Mélanie, Behrmann, Iris, Crespo, Javier, Lu, Shelly C., Mato, José M., Varela-Rey, Marta, Aspichueta, Patricia, Delgado, Teresa C., Martínez-Chantar, María L.
Publicado 2019

Multi-Omics Integration Highlights the Role of Ubiquitination in CCl(4)-Induced Liver Fibrosis

por Mercado-Gómez, Maria, Lopitz-Otsoa, Fernando, Azkargorta, Mikel, Serrano-Maciá, Marina, Lachiondo-Ortega, Sofia, Goikoetxea-Usandizaga, Naroa, Rodríguez-Agudo, Rubén, Fernández-Ramos, David, Bizkarguenaga, Maider, Juan, Virginia Gutiérrez-de, Lectez, Benoît, Aloria, Kerman, Arizmendi, Jesus M., Simon, Jorge, Alonso, Cristina, Lozano, Juan J., Avila, Matias A., Banales, Jesus M., Marin, Jose J. G., Beraza, Naiara, Mato, José M., Elortza, Félix, Barrio, Rosa, Sutherland, James D., Mayor, Ugo, Martínez-Chantar, María L., Delgado, Teresa C.
Publicado 2020

Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury

por Iruzubieta, Paula, Goikoetxea-Usandizaga, Naroa, Barbier-Torres, Lucía, Serrano-Maciá, Marina, Fernández-Ramos, David, Fernández-Tussy, Pablo, Gutiérrez-de-Juan, Virginia, Lachiondo-Ortega, Sofia, Simon, Jorge, Bravo, Miren, Lopitz-Otsoa, Fernando, Robles, Mercedes, Ferre-Aracil, Carlos, Varela-Rey, Marta, Elguezabal, Natalia, Calleja, José Luis, Lu, Shelly C., Milkiewicz, Malgorzata, Milkiewicz, Piotr, Anguita, Juan, Monte, María J., Marin, José J.G., López-Hoyos, Marcos, Delgado, Teresa C., Rincón, Mercedes, Crespo, Javier, Martínez-Chantar, María Luz
Publicado 2021

Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen

por Rodríguez-Agudo, Rubén, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, Fernández-Tussy, Pablo, Fernández-Ramos, David, Lachiondo-Ortega, Sofía, González-Recio, Irene, Gil-Pitarch, Clàudia, Mercado-Gómez, María, Morán, Laura, Bizkarguenaga, Maider, Lopitz-Otsoa, Fernando, Petrov, Petar, Bravo, Miren, Van Liempd, Sebastiaan Martijn, Falcon-Perez, Juan Manuel, Zabala-Letona, Amaia, Carracedo, Arkaitz, Castell, Jose Vicente, Jover, Ramiro, Martínez-Cruz, Luis Alfonso, Delgado, Teresa Cardoso, Cubero, Francisco Javier, Lucena, María Isabel, Andrade, Raúl Jesús, Mabe, Jon, Simón, Jorge, Martínez-Chantar, María Luz
Publicado 2022

Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis

por Serrano-Maciá, Marina, Simón, Jorge, González-Rellan, Maria J., Azkargorta, Mikel, Goikoetxea-Usandizaga, Naroa, Lopitz-Otsoa, Fernando, De Urturi, Diego Saenz, Rodríguez-Agudo, Rubén, Lachiondo-Ortega, Sofia, Mercado-Gomez, Maria, Gutiérrez de Juan, Virginia, Bizkarguenaga, Maider, Fernández-Ramos, David, Buque, Xabier, Baselli, Guido A., Valenti, Luca V.C., Iruzubieta, Paula, Crespo, Javier, Villa, Erica, Banales, Jesus M., Avila, Matias A., Marin, Jose J.G., Aspichueta, Patricia, Sutherland, James, Barrio, Rosa, Mayor, Ugo, Elortza, Félix, Xirodimas, Dimitris P., Nogueiras, Rubén, Delgado, Teresa C., Martínez-Chantar, María Luz
Publicado 2021

Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage

por González-Recio, Irene, Simón, Jorge, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, Mercado-Gómez, Maria, Rodríguez-Agudo, Rubén, Lachiondo-Ortega, Sofía, Gil-Pitarch, Clàudia, Fernández-Rodríguez, Carmen, Castellana, Donatello, Latasa, Maria U., Abecia, Leticia, Anguita, Juan, Delgado, Teresa C., Iruzubieta, Paula, Crespo, Javier, Hardy, Serge, Petrov, Petar D., Jover, Ramiro, Avila, Matías A., Martín, César, Schaeper, Ute, Tremblay, Michel L., Dear, James W., Masson, Steven, McCain, Misti Vanette, Reeves, Helen L., Andrade, Raul J., Lucena, M. Isabel, Buccella, Daniela, Martínez-Cruz, Luis Alfonso, Martínez-Chantar, Maria L
Publicado 2022

Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH

por Simón, Jorge, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, Fernández-Ramos, David, Sáenz de Urturi, Diego, Gruskos, Jessica J., Fernández-Tussy, Pablo, Lachiondo-Ortega, Sofía, González-Recio, Irene, Rodríguez-Agudo, Rubén, Gutiérrez-de-Juan, Virginia, Rodríguez-Iruretagoyena, Begoña, Varela-Rey, Marta, Gimenez-Mascarell, Paula, Mercado-Gomez, María, Gómez-Santos, Beatriz, Fernandez-Rodriguez, Carmen, Lopitz-Otsoa, Fernando, Bizkarguenaga, Maider, Dames, Sibylle, Schaeper, Ute, Martin, Franz, Sabio, Guadalupe, Iruzubieta, Paula, Crespo, Javier, Aspichueta, Patricia, Chu, Kevan H.-Y., Buccella, Daniela, Martín, César, Delgado, Teresa Cardoso, Martínez-Cruz, Luis Alfonso, Martínez-Chantar, María Luz
Publicado 2021

Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals

por Goikoetxea‐Usandizaga, Naroa, Serrano‐Maciá, Marina, Delgado, Teresa C., Simón, Jorge, Fernández Ramos, David, Barriales, Diego, Cornide, Maria E., Jiménez, Mónica, Pérez‐Redondo, Marina, Lachiondo‐Ortega, Sofia, Rodríguez‐Agudo, Rubén, Bizkarguenaga, Maider, Zalamea, Juan Diego, Pasco, Samuel T., Caballero‐Díaz, Daniel, Alfano, Benedetta, Bravo, Miren, González‐Recio, Irene, Mercado‐Gómez, Maria, Gil‐Pitarch, Clàudia, Mabe, Jon, Gracia‐Sancho, Jordi, Abecia, Leticia, Lorenzo, Óscar, Martín‐Sanz, Paloma, Abrescia, Nicola G. A., Sabio, Guadalupe, Rincón, Mercedes, Anguita, Juan, Miñambres, Eduardo, Martín, César, Berenguer, Marina, Fabregat, Isabel, Casado, Marta, Peralta, Carmen, Varela‐Rey, Marta, Martínez‐Chantar, María Luz
Publicado 2021

The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent

por Goikoetxea-Usandizaga, Naroa, Bravo, Miren, Egia-Mendikute, Leire, Abecia, Leticia, Serrano-Maciá, Marina, Urdinguio, Rocío G., Clos-García, Marc, Rodríguez-Agudo, Rubén, Araujo-Legido, Raquel, López-Bermudo, Lucía, Delgado, Teresa C., Lachiondo-Ortega, Sofía, González-Recio, Irene, Gil-Pitarch, Clàudia, Peña-Cearra, Ainize, Simón, Jorge, Benedé-Ubieto, Raquel, Ariño, Silvia, Herranz, Jose M., Azkargorta, Mikel, Salazar-Bermeo, Julio, Martí, Nuria, Varela-Rey, Marta, Falcón-Pérez, Juan M., Lorenzo, Óscar, Nogueiras, Rubén, Elortza, Félix, Nevzorova, Yulia A., Cubero, Francisco J., Saura, Domingo, Martínez-Cruz, Luis Alfonso, Sabio, Guadalupe, Palazón, Asís, Sancho-Bru, Pau, Elguezabal, Natalia, Fraga, Mario F., Ávila, Matías A., Bataller, Ramón, Marín, José J.G., Martín, Franz, Martínez-Chantar, María Luz
Publicado 2023

Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting

por Capelo-Diz, Alba, Lachiondo-Ortega, Sofía, Fernández-Ramos, David, Cañas-Martín, Jorge, Goikoetxea-Usandizaga, Naroa, Serrano-Maciá, Marina, González-Rellan, Maria J., Mosca, Laura, Blazquez-Vicens, Joan, Tinahones-Ruano, Alberto, Fondevila, Marcos F., Buyan, Mason, Delgado, Teresa C., Gutierrez de Juan, Virginia, Ayuso-García, Paula, Sánchez-Rueda, Alejandro, Velasco-Avilés, Sergio, Fernández-Susavila, Héctor, Riobello-Suárez, Cristina, Dziechciarz, Bartlomiej, Montiel-Duarte, Cristina, Lopitz-Otsoa, Fernando, Bizkarguenaga, Maider, Bilbao-García, Jon, Bernardo-Seisdedos, Ganeko, Senra, Ana, Soriano-Navarro, Mario, Millet, Oscar, Díaz-Lagares, Ángel, Crujeiras, Ana B., Bao-Caamano, Aida, Cabrera, Diana, van Liempd, Sebastiaan, Tamayo-Caro, Miguel, Borzacchiello, Luigi, Gomez-Santos, Beatriz, Buqué, Xabier, Sáenz de Urturi, Diego, González-Romero, Francisco, Simon, Jorge, Rodríguez-Agudo, Rubén, Ruiz, Asier, Matute, Carlos, Beiroa, Daniel, Falcon-Perez, Juan M., Aspichueta, Patricia, Rodríguez-Cuesta, Juan, Porcelli, Marina, Pajares, María A., Ameneiro, Cristina, Fidalgo, Miguel, Aransay, Ana M., Lama-Díaz, Tomas, Blanco, Miguel G., López, Miguel, Villa-Bellosta, Ricardo, Müller, Timo D., Nogueiras, Rubén, Woodhoo, Ashwin, Martínez-Chantar, María Luz, Varela-Rey, Marta
Publicado 2023