Functional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR–Cas9-mediated mutagenesis

por Seruggia, Davide, Fernández, Almudena, Cantero, Marta, Pelczar, Pawel, Montoliu, Lluis
Publicado 2015

Boundary sequences flanking the mouse tyrosinase locus ensure faithful pattern of gene expression

por Seruggia, Davide, Fernández, Almudena, Cantero, Marta, Fernández-Miñán, Ana, Gomez-Skarmeta, José Luis, Pelczar, Pawel, Montoliu, Lluis
Publicado 2020

Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs

por Salerno, Domenico, Brogioli, Doriano, Cassina, Valeria, Turchi, Diana, Beretta, Giovanni Luca, Seruggia, Davide, Ziano, Roberto, Zunino, Franco, Mantegazza, Francesco
Publicado 2010

In vivo CRISPR/Cas9 screening identifies Pbrm1 as a regulator of myeloid leukemia development in mice

por Li, Bin E., Li, Grace Y., Cai, Wenqing, Zhu, Qian, Seruggia, Davide, Fujiwara, Yuko, Vakoc, Christopher R., Orkin, Stuart H.
Publicado 2023

Binary recombinase systems for high-resolution conditional mutagenesis

por Hermann, Mario, Stillhard, Patrick, Wildner, Hendrik, Seruggia, Davide, Kapp, Viktor, Sánchez-Iranzo, Héctor, Mercader, Nadia, Montoliu, Lluís, Zeilhofer, Hanns Ulrich, Pelczar, Pawel
Publicado 2014

A Slc38a8 Mouse Model of FHONDA Syndrome Faithfully Recapitulates the Visual Deficits of Albinism Without Pigmentation Defects

por Guardia, Ana, Fernández, Almudena, Seruggia, Davide, Chotard, Virginie, Sánchez-Castillo, Carla, Kutsyr, Oksana, Sánchez-Sáez, Xavier, Zurita, Esther, Cantero, Marta, Rebsam, Alexandra, Cuenca, Nicolás, Montoliu, Lluís
Publicado 2023

The PEG13-DMR and brain-specific enhancers dictate imprinted expression within the 8q24 intellectual disability risk locus

por Court, Franck, Camprubi, Cristina, Garcia, Cristina Vicente, Guillaumet-Adkins, Amy, Sparago, Angela, Seruggia, Davide, Sandoval, Juan, Esteller, Manel, Martin-Trujillo, Alex, Riccio, Andrea, Montoliu, Lluis, Monk, David
Publicado 2014

Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation

por LeBlanc, Lucy, Lee, Bum-Kyu, Yu, Andy C, Kim, Mijeong, Kambhampati, Aparna V, Dupont, Shannon M, Seruggia, Davide, Ryu, Byoung U, Orkin, Stuart H, Kim, Jonghwan
Publicado 2018

Role of PDGFRA(+) cells and a CD55(+) PDGFRA(Lo) fraction in the gastric mesenchymal niche

por Manieri, Elisa, Tie, Guodong, Malagola, Ermanno, Seruggia, Davide, Madha, Shariq, Maglieri, Adrianna, Huang, Kun, Fujiwara, Yuko, Zhang, Kevin, Orkin, Stuart H., Wang, Timothy C., He, Ruiyang, McCarthy, Neil, Shivdasani, Ramesh A.
Publicado 2023

Enhancer dependence of cell-type–specific gene expression increases with developmental age

por Cai, Wenqing, Huang, Jialiang, Zhu, Qian, Li, Bin E., Seruggia, Davide, Zhou, Pingzhu, Nguyen, Minh, Fujiwara, Yuko, Xie, Huafeng, Yang, Zhenggang, Hong, Danni, Ren, Pengfei, Xu, Jian, Pu, William T., Yuan, Guo-Cheng, Orkin, Stuart H.
Publicado 2020

Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer

por Singh, Harshabad, Seruggia, Davide, Madha, Shariq, Saxena, Madhurima, Nagaraja, Ankur K., Wu, Zhong, Zhou, Jin, Huebner, Aaron J., Maglieri, Adrianna, Wezenbeek, Juliette, Hochedlinger, Konrad, Orkin, Stuart H., Bass, Adam J., Hornick, Jason L., Shivdasani, Ramesh A.
Publicado 2022

Targeting the CBM complex causes Treg cells to prime tumors for immune checkpoint therapy

por Pilato, Mauro Di, Kim, Edward Y., Cadilha, Bruno L., Pruessmann, Jasper N., Nasrallah, Mazen N., Seruggia, Davide, Usmani, Shariq M., Misale, Sandra, Zappulli, Valentina, Carrizosa, Esteban, Mani, Vinidhra, Ligorio, Matteo, Warner, Ross D., Medoff, Benjamin D., Marangoni, Francesco, Villani, Alexandra-Chloe, Mempel, Thorsten R.
Publicado 2019

JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma

por Manieri, Elisa, Folgueira, Cintia, Rodríguez, María Elena, Leiva-Vega, Luis, Esteban-Lafuente, Laura, Chen, Chaobo, Cubero, Francisco Javier, Barrett, Tamera, Cavanagh-Kyros, Julie, Seruggia, Davide, Rosell, Alejandro, Sanchez-Cabo, Fátima, Gómez, Manuel Jose, Monte, Maria J., G. Marin, Jose J., Davis, Roger J., Mora, Alfonso, Sabio, Guadalupe
Publicado 2020

Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis

por Sher, Falak, Hossain, Mir, Seruggia, Davide, Schoonenberg, Vivien A. C., Yao, Qiuming, Cifani, Paolo, Dassama, Laura M. K., Cole, Mitchel A., Ren, Chunyan, Vinjamur, Divya S., Macias-Trevino, Claudio, Luk, Kevin, McGuckin, Connor, Schupp, Patrick G., Canver, Matthew C., Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Wolfe, Scot A., Pinello, Luca, Maeda, Takahiro, Kentsis, Alex, Orkin, Stuart H., Bauer, Daniel E.
Publicado 2019