Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity

por Nancolas, Bethany, Sessions, Richard B., Halestrap, Andrew P.
Publicado 2015

Perhydrohelicenes and other diamond-lattice based hydrocarbons: the choreography of inversion

por Alder, Roger W., Butts, Craig P., Sessions, Richard B.
Publicado 2017

Drug Binding Poses Relate Structure with Efficacy in the μ Opioid Receptor

por Sutcliffe, Katy J., Henderson, Graeme, Kelly, Eamonn, Sessions, Richard B.
Publicado 2017

The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic...

por Manoharan, Christine, Wilson, Marieangela C., Sessions, Richard B., Halestrap, Andrew P.
Publicado 2006

Bioinformatic analysis of meningococcal Msf and Opc to inform vaccine antigen design

por Andreae, Clio A., Sessions, Richard B., Virji, Mumtaz, Hill, Darryl. J.
Publicado 2018

Intraring allostery controls the function and assembly of a hetero-oligomeric class II chaperonin

por Shoemark, Deborah K., Sessions, Richard B., Brancaccio, Andrea, Bigotti, Maria Giulia
Publicado 2018

Mutational analysis of human CEACAM1: the potential of receptor polymorphism in increasing host susceptibility to bacterial infection

por Villullas, Silvia, Hill, Darryl J, Sessions, Richard B, Rea, Jon, Virji, Mumtaz
Publicado 2007

High performance in silico virtual drug screening on many-core processors

por McIntosh-Smith, Simon, Price, James, Sessions, Richard B, Ibarra, Amaurys A
Publicado 2015

Studies on the DIDS-binding Site of Monocarboxylate Transporter 1 Suggest a Homology Model of the Open Conformation and a Plausible Translocation Cycle

por Wilson, Marieangela C., Meredith, David, Bunnun, Chotirote, Sessions, Richard B., Halestrap, Andrew P.
Publicado 2009

Internal (His)(6)-tagging delivers a fully functional hetero-oligomeric class II chaperonin in high yield

por Paul, Danielle M., Beuron, Fabienne, Sessions, Richard B., Brancaccio, Andrea, Bigotti, Maria Giulia
Publicado 2016

Identification and validation of novel microtubule suppressors with an imidazopyridine scaffold through structure-based virtual screening and docking

por Elseginy, Samia A., Oliveira, A. Sofia F., Shoemark, Deborah K., Sessions, Richard B.
Publicado 2022

Assessing hERG Pore Models As Templates for Drug Docking Using Published Experimental Constraints: The Inactivated State in the Context of Drug Block

por Dempsey, Christopher E., Wright, Dominic, Colenso, Charlotte K., Sessions, Richard B., Hancox, Jules C.
Publicado 2014

Voltage Sensor Gating Charge Transfer in a hERG Potassium Channel Model

por Colenso, Charlotte K., Cao, Yang, Sessions, Richard B., Hancox, Jules C., Dempsey, Christopher E.
Publicado 2014

A Switch in the Mechanism of Communication between the Two DNA-Binding Sites in the SfiI Restriction Endonuclease

por Bellamy, Stuart R.W., Milsom, Susan E., Kovacheva, Yana S., Sessions, Richard B., Halford, Stephen E.
Publicado 2007

The hERG K(+) channel S4 domain L532P mutation: Characterization at 37 °C

por Zhang, Yi H., Colenso, Charlotte K., Sessions, Richard B., Dempsey, Christopher E., Hancox, Jules C.
Publicado 2011

Stapled Peptides as HIF‐1α/p300 Inhibitors: Helicity Enhancement in the Bound State Increases Inhibitory Potency

por Hetherington, Kristina, Hegedus, Zsofia, Edwards, Thomas A., Sessions, Richard B., Nelson, Adam, Wilson, Andrew J.
Publicado 2020

Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex

por Whitehouse, Sarah, Gold, Vicki A.M., Robson, Alice, Allen, William J., Sessions, Richard B., Collinson, Ian
Publicado 2012

Identification and Therapeutic Potential of a Vitronectin Binding Region of Meningococcal Msf

por Hill, Darryl J., Griffiths, Natalie J., Borodina, Elena, Andreae, Clio A., Sessions, Richard B., Virji, Mumtaz
Publicado 2015

Interaction of the Antimicrobial Peptide Polymyxin B1 with Both Membranes of E. coli: A Molecular Dynamics Study

por Berglund, Nils A., Piggot, Thomas J., Jefferies, Damien, Sessions, Richard B., Bond, Peter J., Khalid, Syma
Publicado 2015

FKBP12.6 Activates RyR1: Investigating the Amino Acid Residues Critical for Channel Modulation

por Venturi, Elisa, Galfré, Elena, O’Brien, Fiona, Pitt, Samantha J., Bellamy, Stuart, Sessions, Richard B., Sitsapesan, Rebecca
Publicado 2014