The Δ4-desaturation pathway for DHA biosynthesis is operative in the human species: Differences between normal controls and children with the Zellweger syndrome

por Martinez, Manuela, Ichaso, Natalia, Setien, Fernando, Durany, Nuria, Qiu, Xiao, Roesler, William
Publicado 2010

PB1705: THE HISTONE MODIFIER SETD6 IS EPIGENETICALLY REGULATED IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND INTERFERES WITH PROLIFERATION AND GENE EXPRESSION

por Veselinova, Yoana, Campillo-Marcos, Ignacio, Rossello-Tortella, Margalida, Setien, Fernando, Ferrer, Gerardo, Esteller, Manel
Publicado 2023

Impact of the Epigenetically Regulated Hoxa-5 Gene in Neural Differentiation from Human Adipose-Derived Stem Cells

por Hernández, Rosa, Jiménez-Luna, Cristina, Ortiz, Raúl, Setién, Fernando, López, Miguel, Perazzoli, Gloria, Esteller, Manel, Berdasco, María, Prados, Jose, Melguizo, Consolación
Publicado 2021

The transcribed ultraconserved region uc.160+ enhances processing and A‐to‐I editing of the miR‐376 cluster: hypermethylation improves glioma prognosis

por Soler, Marta, Davalos, Veronica, Sánchez‐Castillo, Anaís, Mora‐Martinez, Carlos, Setién, Fernando, Siqueira, Edilene, Castro de Moura, Manuel, Esteller, Manel, Guil, Sonia
Publicado 2021

The tumour suppressor and chromatin-remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer

por Romero, Octavio A, Setien, Fernando, John, Sam, Gimenez-Xavier, Pol, Gómez-López, Gonzalo, Pisano, David, Condom, Enric, Villanueva, Alberto, Hager, Gordon L, Sanchez-Cespedes, Montse
Publicado 2012

Circular RNA CpG island hypermethylation-associated silencing in human cancer

por Ferreira, Humberto J., Davalos, Veronica, de Moura, Manuel Castro, Soler, Marta, Perez-Salvia, Montserrat, Bueno-Costa, Alberto, Setien, Fernando, Moran, Sebastian, Villanueva, Alberto, Esteller, Manel
Publicado 2018

Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context

por Espada, Jesús, Peinado, Hector, Lopez-Serra, Lidia, Setién, Fernando, Lopez-Serra, Paula, Portela, Anna, Renart, Jaime, Carrasco, Elisa, Calvo, María, Juarranz, Angeles, Cano, Amparo, Esteller, Manel
Publicado 2011

Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer

por Pérez-Salvia, Montserrat, Simó-Riudalbas, Laia, Llinàs-Arias, Pere, Roa, Laura, Setien, Fernando, Soler, Marta, de Moura, Manuel Castro, Bradner, James E., Gonzalez-Suarez, Eva, Moutinho, Catia, Esteller, Manel
Publicado 2017

Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer

por Palomeras, Sònia, Diaz-Lagares, Ángel, Viñas, Gemma, Setien, Fernando, Ferreira, Humberto J., Oliveras, Glòria, Crujeiras, Ana B., Hernández, Alejandro, Lum, David H., Welm, Alana L., Esteller, Manel, Puig, Teresa
Publicado 2019

Epigenetic loss of the transfer RNA-modifying enzyme TYW2 induces ribosome frameshifts in colon cancer

por Rosselló-Tortella, Margalida, Llinàs-Arias, Pere, Sakaguchi, Yuriko, Miyauchi, Kenjyo, Davalos, Veronica, Setien, Fernando, Calleja-Cervantes, Maria E., Piñeyro, David, Martínez-Gómez, Jesús, Guil, Sonia, Joshi, Ricky, Villanueva, Alberto, Suzuki, Tsutomu, Esteller, Manel
Publicado 2020

Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer

por Coll-SanMartin, Laia, Davalos, Veronica, Piñeyro, David, Rosselló-Tortella, Margalida, Bueno-Costa, Alberto, Setien, Fernando, Villanueva, Alberto, Granada, Isabel, Ruiz-Xiviller, Neus, Kotter, Annika, Helm, Mark, Yokota, Jun, Kawabata-Iwakawa, Reika, Kohno, Takashi, Esteller, Manel
Publicado 2021

Analysis of the circRNA and T-UCR populations identifies convergent pathways in mouse and human models of Rett syndrome

por Siqueira, Edilene, Obiols-Guardia, Aida, Jorge-Torres, Olga C., Oliveira-Mateos, Cristina, Soler, Marta, Ramesh-Kumar, Deepthi, Setién, Fernando, van Rossum, Daniëlle, Pascual-Alonso, Ainhoa, Xiol, Clara, Ivan, Cristina, Shimizu, Masayoshi, Armstrong, Judith, Calin, George A., Pasterkamp, R. Jeroen, Esteller, Manel, Guil, Sonia
Publicado 2021

SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade

por Romero, Octavio A., Vilarrubi, Andrea, Alburquerque-Bejar, Juan J., Gomez, Antonio, Andrades, Alvaro, Trastulli, Deborah, Pros, Eva, Setien, Fernando, Verdura, Sara, Farré, Lourdes, Martín-Tejera, Juan F., Llabata, Paula, Oaknin, Ana, Saigi, Maria, Piulats, Josep M., Matias-Guiu, Xavier, Medina, Pedro P., Vidal, August, Villanueva, Alberto, Sanchez-Cespedes, Montse
Publicado 2021

Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer

por Ortiz-Barahona, Vanessa, Soler, Marta, Davalos, Veronica, García-Prieto, Carlos A., Janin, Maxime, Setien, Fernando, Fernández-Rebollo, Irene, Bech-Serra, Joan J., De La Torre, Carolina, Guil, Sonia, Villanueva, Alberto, Zhang, Pei-Hong, Yang, Li, Guarnacci, Marco, Schumann, Ulrike, Preiss, Thomas, Balaseviciute, Ugne, Montal, Robert, Llovet, Josep M., Esteller, Manel
Publicado 2023

Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis

por Mur, Pilar, De Voer, Richarda M., Olivera-Salguero, Rubén, Rodríguez-Perales, Sandra, Pons, Tirso, Setién, Fernando, Aiza, Gemma, Valdés-Mas, Rafael, Bertini, Angelo, Pineda, Marta, Vreede, Lilian, Navarro, Matilde, Iglesias, Silvia, González, Sara, Brunet, Joan, Valencia, Alfonso, Esteller, Manel, Lázaro, Conxi, Kops, Geert J. P. L., Urioste, Miguel, Puente, Xose S., Capellá, Gabriel, Valle, Laura
Publicado 2018

Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19

por Solanich, Xavier, Vargas-Parra, Gardenia, van der Made, Caspar I., Simons, Annet, Schuurs-Hoeijmakers, Janneke, Antolí, Arnau, del Valle, Jesús, Rocamora-Blanch, Gemma, Setién, Fernando, Esteller, Manel, van Reijmersdal, Simon V., Riera-Mestre, Antoni, Sabater-Riera, Joan, Capellá, Gabriel, van de Veerdonk, Frank L., van der Hoven, Ben, Corbella, Xavier, Hoischen, Alexander, Lázaro, Conxi
Publicado 2021

A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li–Fraumeni-like families

por Calvete, Oriol, Martinez, Paula, Garcia-Pavia, Pablo, Benitez-Buelga, Carlos, Paumard-Hernández, Beatriz, Fernandez, Victoria, Dominguez, Fernando, Salas, Clara, Romero-Laorden, Nuria, Garcia-Donas, Jesus, Carrillo, Jaime, Perona, Rosario, Triviño, Juan Carlos, Andrés, Raquel, Cano, Juana María, Rivera, Bárbara, Alonso-Pulpon, Luis, Setien, Fernando, Esteller, Manel, Rodriguez-Perales, Sandra, Bougeard, Gaelle, Frebourg, Tierry, Urioste, Miguel, Blasco, Maria A., Benítez, Javier
Publicado 2015

DNA Methylomes Reveal Biological Networks Involved in Human Eye Development, Functions and Associated Disorders

por Berdasco, María, Gómez, Antonio, Rubio, Marcos J., Català-Mora, Jaume, Zanón-Moreno, Vicente, Lopez, Miguel, Hernández, Cristina, Yoshida, Shigeo, Nakama, Takahito, Ishikawa, Keijiro, Ishibashi, Tatsuro, Boubekeur, Amina M., Louhibi, Lotfi, Pujana, Miguel A, Sayols, Sergi, Setien, Fernando, Corella, Dolores, de Torres, Carmen, Parareda, Andreu, Mora, Jaume, Zhao, Ling, Zhang, Kang, Lleonart, Matilde E., Alonso, Javier, Simó, Rafael, Caminal, Josep M., Esteller, Manel
Publicado 2017