Optimizing the treatment of BRAF mutant melanoma

por Settleman, Jeff
Publicado 2014

Predicting response to HER2 kinase inhibition

por Settleman, Jeff
Publicado 2014

Integrating complex genomic datasets and tumour cell sensitivity profiles to address a 'simple' question: which patients should get this drug?

por Benes, Cyril, Settleman, Jeff
Publicado 2009

Discovering Tumor Suppressor Genes Through Genome-Wide Copy Number Analysis

por Rothenberg, S. Michael, Settleman, Jeff
Publicado 2010

Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein

por Deuker, Marian M., Lewis, Kaitlyn N., Ingaramo, Maria, Kimmel, Jacob, Buffenstein, Rochelle, Settleman, Jeff
Publicado 2020

Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition

por Wilson, Catherine, Nicholes, Katrina, Bustos, Daisy, Lin, Eva, Song, Qinghua, Stephan, Jean-Philippe, Kirkpatrick, Donald S., Settleman, Jeff
Publicado 2014

Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs

por Sahu, Nisebita, Stephan, Jean-Philippe, Cruz, Darlene Dela, Merchant, Mark, Haley, Benjamin, Bourgon, Richard, Classon, Marie, Settleman, Jeff
Publicado 2016

Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells

por Sun, Yuting, Daemen, Anneleen, Hatzivassiliou, Georgia, Arnott, David, Wilson, Catherine, Zhuang, Guanglei, Gao, Min, Liu, Peter, Boudreau, Aaron, Johnson, Leisa, Settleman, Jeff
Publicado 2014

Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations

por GALIMBERTI, FABRIZIO, BUSCH, ALEXANDER M., CHINYENGETERE, FADZAI, MA, TIAN, SEKULA, DAVID, MEMOLI, VINCENT A., DRAGNEV, KONSTANTIN H., LIU, FANG, JOHNSON, KEVIN C., GUO, YONGLI, FREEMANTLE, SARAH J., ANDREW, ANGELINE S., GRENINGER, PATRICIA, ROBBINS, DAVID J., SETTLEMAN, JEFF, BENES, CYRIL, DMITROVSKY, ETHAN
Publicado 2012

Transcriptional control of the autophagy-lysosome system in pancreatic cancer

por Perera, Rushika M., Stoykova, Svetlana, Nicolay, Brandon N., Ross, Kenneth N., Fitamant, Julien, Boukhali, Myriam, Lengrand, Justine, Deshpande, Vikram, Selig, Martin K., Ferrone, Cristina R., Settleman, Jeff, Stephanopoulos, Gregory, Dyson, Nicholas J., Zoncu, Roberto, Ramaswamy, Sridhar, Haas, Wilhelm, Bardeesy, Nabeel
Publicado 2015

High Heregulin Expression Is Associated with Activated HER3 and May Define an Actionable Biomarker in Patients with Squamous Cell Carcinomas of the Head and Neck

por Shames, David S., Carbon, Juliet, Walter, Kim, Jubb, Adrian M., Kozlowski, Cleopatra, Januario, Tom, An, Do, Fu, Ling, Xiao, Yuanyuan, Raja, Rajiv, Jiang, Brittany, Malekafzali, Ashi, Stern, Howard, Settleman, Jeff, Wilson, Timothy R., Hampton, Garret M., Yauch, Robert L., Pirzkall, Andrea, Amler, Lukas C.
Publicado 2013

Correction: High Heregulin Expression Is Associated with Activated HER3 and May Define an Actionable Biomarker in Patients with Squamous Cell Carcinomas of the Head and Neck

por Shames, David S., Carbon, Juliet, Walter, Kim, Jubb, Adrian M., Kozlowski, Cleopatra, Januario, Tom, Do, An, Fu, Ling, Xiao, Yuanyuan, Raja, Rajiv, Jiang, Brittany, Malekafzali, Ashi, Stern, Howard, Settleman, Jeff, Wilson, Timothy R., Hampton, Garret M., Yauch, Robert L., Pirzkall, Andrea, Amler, Lukas C.
Publicado 2013

Targeting microtubules sensitizes drug resistant lung cancer cells to lysosomal pathway inhibitors

por Chin, Tan-Min, Boopathy, Gandhi T. K., Man, Ellen P.S., Clohessy, John G., Csizmadia, Eva, Quinlan, Margaret P, Putti, Thomas, Wan, Seow-Ching, Xie, Chen, Ali, Azhar, Wai, Fhu Chee, Ong, Yan Shan, Goh, Boon-Cher, Settleman, Jeff, Hong, Wanjin, Levantini, Elena, Tenen, Daniel G.
Publicado 2020

Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events

por Liu, Jinfeng, Lee, William, Jiang, Zhaoshi, Chen, Zhongqiang, Jhunjhunwala, Suchit, Haverty, Peter M., Gnad, Florian, Guan, Yinghui, Gilbert, Houston N., Stinson, Jeremy, Klijn, Christiaan, Guillory, Joseph, Bhatt, Deepali, Vartanian, Steffan, Walter, Kimberly, Chan, Jocelyn, Holcomb, Thomas, Dijkgraaf, Peter, Johnson, Stephanie, Koeman, Julie, Minna, John D., Gazdar, Adi F., Stern, Howard M., Hoeflich, Klaus P., Wu, Thomas D., Settleman, Jeff, de Sauvage, Frederic J., Gentleman, Robert C., Neve, Richard M., Stokoe, David, Modrusan, Zora, Seshagiri, Somasekar, Shames, David S., Zhang, Zemin
Publicado 2012