Mapping CRISPR spaceromes reveals vast host-specific viromes of prokaryotes

por Shmakov, Sergey A., Wolf, Yuri I., Savitskaya, Ekaterina, Severinov, Konstantin V., Koonin, Eugene V.
Publicado 2020

Type III CRISPR-Cas Systems: Deciphering the Most Complex Prokaryotic Immune System

por Kolesnik, Matvey V., Fedorova, Iana, Karneyeva, Karyna A., Artamonova, Daria N., Severinov, Konstantin V.
Publicado 2021

The CRISPR Spacer Space Is Dominated by Sequences from Species-Specific Mobilomes

por Shmakov, Sergey A., Sitnik, Vassilii, Makarova, Kira S., Wolf, Yuri I., Severinov, Konstantin V., Koonin, Eugene V.
Publicado 2017

Uncertainty-aware and interpretable evaluation of Cas9–gRNA and Cas12a–gRNA specificity for fully matched and partially mismatched targets with Deep Kernel Learning

por Kirillov, Bogdan, Savitskaya, Ekaterina, Panov, Maxim, Ogurtsov, Aleksey Y, Shabalina, Svetlana A, Koonin, Eugene V, Severinov, Konstantin V
Publicado 2021

Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase

por Fraser, Alec, Sokolova, Maria L., Drobysheva, Arina V., Gordeeva, Julia V., Borukhov, Sergei, Jumper, John, Severinov, Konstantin V., Leiman, Petr G.
Publicado 2022

Analysis of the mechanism of nucleosome survival during transcription

por Chang, Han-Wen, Kulaeva, Olga I., Shaytan, Alexey K., Kibanov, Mikhail, Kuznedelov, Konstantin, Severinov, Konstantin V., Kirpichnikov, Mikhail P., Clark, David J., Studitsky, Vasily M.
Publicado 2014

Novel Fri1-like Viruses Infecting Acinetobacter baumannii—vB_AbaP_AS11 and vB_AbaP_AS12—Characterization, Comparative Genomic Analysis, and Host-Recognition Strategy

por Popova, Anastasia V., Lavysh, Daria G., Klimuk, Evgeniy I., Edelstein, Mikhail V., Bogun, Alexander G., Shneider, Mikhail M., Goncharov, Artemiy E., Leonov, Sergey V., Severinov, Konstantin V.
Publicado 2017

Liquid drop of DNA libraries reveals total genome information

por Terekhov, Stanislav S., Eliseev, Igor E., Ovchinnikova, Leyla A., Kabilov, Marsel R., Prjibelski, Andrey D., Tupikin, Alexey E., Smirnov, Ivan V., Belogurov, Alexey A., Severinov, Konstantin V., Lomakin, Yakov A., Altman, Sidney, Gabibov, Alexander G.
Publicado 2020

New Infestin-4 Mutants with Increased Selectivity against Factor XIIa

por Kolyadko, Vladimir N., Lushchekina, Sofya V., Vuimo, Tatiana A., Surov, Stepan S., Ovsepyan, Ruzanna A., Korneeva, Vera A., Vorobiev, Ivan I., Orlova, Nadezhda A., Minakhin, Leonid, Kuznedelov, Konstantin, Severinov, Konstantin V., Ataullakhanov, Fazoil I., Panteleev, Mikhail A.
Publicado 2015

Ultrahigh-throughput functional profiling of microbiota communities

por Terekhov, Stanislav S., Smirnov, Ivan V., Malakhova, Maja V., Samoilov, Andrei E., Manolov, Alexander I., Nazarov, Anton S., Danilov, Dmitry V., Dubiley, Svetlana A., Osterman, Ilya A., Rubtsova, Maria P., Kostryukova, Elena S., Ziganshin, Rustam H., Kornienko, Maria A., Vanyushkina, Anna A., Bukato, Olga N., Ilina, Elena N., Vlasov, Valentin V., Severinov, Konstantin V., Gabibov, Alexander G., Altman, Sidney
Publicado 2018