Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation

por Severson, Paul L., Tokar, Erik J., Vrba, Lukas, Waalkes, Michael P., Futscher, Bernard W.
Publicado 2012

Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation

por Severson, Paul L, Tokar, Erik J, Vrba, Lukas, Waalkes, Michael P, Futscher, Bernard W
Publicado 2013

A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemia

por Lee, Lauren Y., Hizukuri, Yoshiyuki, Severson, Paul, Powell, Benjamin, Zhang, Chao, Ma, Yan, Narahara, Maiko, Sumi, Hiroyuki, Hernandez, Daniela, Rajkhowa, Trivikram, Bollag, Gideon, Levis, Mark
Publicado 2021

Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors

por Wesolowski, Robert, Sharma, Neelesh, Reebel, Laura, Rodal, Mary Beth, Peck, Alexandra, West, Brian L., Marimuthu, Adhirai, Severson, Paul, Karlin, David A., Dowlati, Afshin, Le, Mai H., Coussens, Lisa M., Rugo, Hope S.
Publicado 2019

Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma

por Sathyasaikumar, Korrapati V., Pérez de la Cruz, Verónica, Pineda, Benjamín, Vázquez Cervantes, Gustavo Ignacio, Ramírez Ortega, Daniela, Donley, David W., Severson, Paul L., West, Brian L., Giorgini, Flaviano, Fox, Jonathan H., Schwarcz, Robert
Publicado 2022

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

por Spangenberg, Elizabeth, Severson, Paul L., Hohsfield, Lindsay A., Crapser, Joshua, Zhang, Jiazhong, Burton, Elizabeth A., Zhang, Ying, Spevak, Wayne, Lin, Jack, Phan, Nicole Y., Habets, Gaston, Rymar, Andrey, Tsang, Garson, Walters, Jason, Nespi, Marika, Singh, Parmveer, Broome, Stephanie, Ibrahim, Prabha, Zhang, Chao, Bollag, Gideon, West, Brian L., Green, Kim N.
Publicado 2019

Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT

por Tap, William D., Singh, Arun S., Anthony, Stephen Patrick, Sterba, Mike, Zhang, Chao, Healey, John H., Chmielowski, Bartosz, Cohn, Allen Lee, Shapiro, Geoffrey I., Keedy, Vicki L., Wainberg, Zev A., Puzanov, Igor, Cote, Gregory M., Wagner, Andrew J., Braiteh, Fadi, Sherman, Eric, Hsu, Henry H., Peterfy, Charles, Gelhorn, Heather L., Ye, Xin, Severson, Paul, West, Brian L., Lin, Paul S., Tong-Starksen, Sandra
Publicado 2022