Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models

por Vossen, Michaela, Sevestre, Michael, Niederalt, Christoph, Jang, In-Jin, Willmann, Stefan, Edginton, Andrea N
Publicado 2007

Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO

por Watt, Kevin M., Cohen‐Wolkowiez, Michael, Barrett, Jeffrey S., Sevestre, Michael, Zhao, Ping, Brouwer, Kim L.R., Edginton, Andrea N.
Publicado 2018

User-Centered Development and Testing of the Online Patient-Reported Outcomes, Burdens, and Experiences (PROBE) Survey and the myPROBE App and Integration With the Canadian Bleedin...

por Germini, Federico, Borg Debono, Victoria, Page, David, Zuk, Victoria, Kucher, Alexandra, Cotoi, Chris, Hobson, Nicholas, Sevestre, Michael, Skinner, Mark W, Iorio, Alfonso
Publicado 2022

Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences

por Lippert, Jörg, Burghaus, Rolf, Edginton, Andrea, Frechen, Sebastian, Karlsson, Mats, Kovar, Andreas, Lehr, Thorsten, Milligan, Peter, Nock, Valerie, Ramusovic, Sergej, Riggs, Matthew, Schaller, Stephan, Schlender, Jan, Schmidt, Stephan, Sevestre, Michaël, Sjögren, Erik, Solodenko, Juri, Staab, Alexander, Teutonico, Donato
Publicado 2019

A Computational Systems Biology Software Platform for Multiscale Modeling and Simulation: Integrating Whole-Body Physiology, Disease Biology, and Molecular Reaction Networks

por Eissing, Thomas, Kuepfer, Lars, Becker, Corina, Block, Michael, Coboeken, Katrin, Gaub, Thomas, Goerlitz, Linus, Jaeger, Juergen, Loosen, Roland, Ludewig, Bernd, Meyer, Michaela, Niederalt, Christoph, Sevestre, Michael, Siegmund, Hans-Ulrich, Solodenko, Juri, Thelen, Kirstin, Telle, Ulrich, Weiss, Wolfgang, Wendl, Thomas, Willmann, Stefan, Lippert, Joerg
Publicado 2011