Calcitonin/Amylin Receptors and Ramps

por Sexton, Patrick M.
Publicado 2001

Allosteric Modulation of Muscarinic Acetylcholine Receptors

por Gregory, Karen J, Sexton, Patrick M, Christopoulos, Arthur
Publicado 2007

Improving virtual screening of G protein-coupled receptors via ligand-directed modeling

por Coudrat, Thomas, Simms, John, Christopoulos, Arthur, Wootten, Denise, Sexton, Patrick M.
Publicado 2017

Roles of Cholecystokinin in the Nutritional Continuum. Physiology and Potential Therapeutics

por Miller, Laurence J., Harikumar, Kaleeckal G., Wootten, Denise, Sexton, Patrick M.
Publicado 2021

Membranes under the Magnetic Lens: A Dive into the Diverse World of Membrane Protein Structures Using Cryo-EM

por Piper, Sarah J., Johnson, Rachel M., Wootten, Denise, Sexton, Patrick M.
Publicado 2022

Toward an understanding of the structural basis of allostery in muscarinic acetylcholine receptors

por Burger, Wessel A.C., Sexton, Patrick M., Christopoulos, Arthur, Thal, David M.
Publicado 2018

Exploring Ligand Binding to Calcitonin Gene-Related Peptide Receptors

por Deganutti, Giuseppe, Atanasio, Silvia, Rujan, Roxana-Maria, Sexton, Patrick M., Wootten, Denise, Reynolds, Christopher A.
Publicado 2021

Targeting VIP and PACAP Receptor Signaling: New Insights into Designing Drugs for the PACAP Subfamily of Receptors

por Lu, Jessica, Piper, Sarah J., Zhao, Peishen, Miller, Laurence J., Wootten, Denise, Sexton, Patrick M.
Publicado 2022

Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP...

por Koole, Cassandra, Reynolds, Christopher A., Mobarec, Juan C., Hick, Caroline, Sexton, Patrick M., Sakmar, Thomas P.
Publicado 2017

Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research

por Riddy, Darren M., Goy, Emily, Delerive, Philippe, Summers, Roger J., Sexton, Patrick M., Langmead, Christopher J.
Publicado 2018

Routine sub-2.5 Å cryo-EM structure determination of GPCRs

por Danev, Radostin, Belousoff, Matthew, Liang, Yi-Lynn, Zhang, Xin, Eisenstein, Fabian, Wootten, Denise, Sexton, Patrick M.
Publicado 2021

Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’

por Qin, Cheng Xue, May, Lauren T., Sexton, Patrick M., DeBono, Aaron J., Baell, Jonathan B., Christopoulos, Arthur, Ritchie, Rebecca H.
Publicado 2018

New Insights into the Structure and Function of Class B1 GPCRs

por Cary, Brian P, Zhang, Xin, Cao, Jianjun, Johnson, Rachel M, Piper, Sarah J, Gerrard, Elliot J, Wootten, Denise, Sexton, Patrick M
Publicado 2022

Prolonged Calcitonin Receptor Signaling by Salmon, but Not Human Calcitonin, Reveals Ligand Bias

por Andreassen, Kim Vietz, Hjuler, Sara Toftegaard, Furness, Sebastian G., Sexton, Patrick M., Christopoulos, Arthur, Nosjean, Olivier, Karsdal, Morten Asser, Henriksen, Kim
Publicado 2014

Expression and activity of the calcitonin receptor family in a sample of primary human high-grade gliomas

por Ostrovskaya, Anna, Hick, Caroline, Hutchinson, Dana S., Stringer, Brett W., Wookey, Peter J., Wootten, Denise, Sexton, Patrick M., Furness, Sebastian G. B.
Publicado 2019

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology

por J Gingell, Joseph, Simms, John, Barwell, James, Poyner, David R, Watkins, Harriet A, Pioszak, Augen A, Sexton, Patrick M, Hay, Debbie L
Publicado 2016

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology

por Gingell, Joseph J, Simms, John, Barwell, James, Poyner, David R, Watkins, Harriet A, Pioszak, Augen A, Sexton, Patrick M, Hay, Debbie L
Publicado 2016

Monotreme glucagon-like peptide-1 in venom and gut: one gene – two very different functions

por Tsend-Ayush, Enkhjargal, He, Chuan, Myers, Mark A., Andrikopoulos, Sof, Wong, Nicole, Sexton, Patrick M., Wootten, Denise, Forbes, Briony E., Grutzner, Frank
Publicado 2016

Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in...

por Wootten, Denise, Reynolds, Christopher A., Smith, Kevin J., Mobarec, Juan C., Furness, Sebastian G.B., Miller, Laurence J., Christopoulos, Arthur, Sexton, Patrick M.
Publicado 2016

Probing the binding site of novel selective positive allosteric modulators at the M(1) muscarinic acetylcholine receptor

por Khajehali, Elham, Valant, Celine, Jörg, Manuela, Tobin, Andrew B., Conn, P. Jeffrey, Lindsley, Craig W., Sexton, Patrick M., Scammells, Peter J., Christopoulos, Arthur
Publicado 2018