Emerging strategies and applications of pharmacogenomics

por Milos, Patrice M, Seymour, Albert B
Publicado 2004

siRNA Off-Target Effects Can Be Reduced at Concentrations That Match Their Individual Potency

por Caffrey, Daniel R., Zhao, Juan, Song, Zhili, Schaffer, Michael E., Haney, Steven A., Subramanian, Romesh R., Seymour, Albert B., Hughes, Jason D.
Publicado 2011

Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels

por Hinds, David A, Seymour, Albert B, Durham, L Kathryn, Banerjee, Poulabi, Ballinger, Dennis G, Milos, Patrice M, Cox, David R, Thompson, John F, Frazer, Kelly A
Publicado 2004

Clade F AAVHSCs cross the blood brain barrier and transduce the central nervous system in addition to peripheral tissues following intravenous administration in nonhuman primates

por Ellsworth, Jeff L., Gingras, Jacinthe, Smith, Laura J., Rubin, Hillard, Seabrook, Tania A., Patel, Kruti, Zapata, Nicole, Olivieri, Kevin, O’Callaghan, Michael, Chlipala, Elizabeth, Morales, Pablo, Seymour, Albert
Publicado 2019

Molecular characterization of precise in vivo targeted gene integration in human cells using AAVHSC15

por Chen, Huei-Mei, Resendes, Rachel, Ghodssi, Azita, Sookiasian, Danielle, Tian, Michael, Dollive, Serena, Adamson-Small, Laura, Avila, Nancy, Tazearslan, Cagdas, Thompson, John F., Ellsworth, Jeff L., Francone, Omar, Seymour, Albert, Wright, Jason B.
Publicado 2020

Sustained Correction of a Murine Model of Phenylketonuria following a Single Intravenous Administration of AAVHSC15-PAH

por Ahmed, Seemin S., Rubin, Hillard, Wang, Minglun, Faulkner, Deiby, Sengooba, Arnold, Dollive, Serena N., Avila, Nancy, Ellsworth, Jeff L., Lamppu, Diana, Lobikin, Maria, Lotterhand, Jason, Adamson-Small, Laura, Wright, Teresa, Seymour, Albert, Francone, Omar L.
Publicado 2020

Natural variations in AAVHSC16 significantly reduce liver tropism and maintain broad distribution to periphery and CNS

por Smith, Laura J., Schulman, Lindsay A., Smith, Samantha, Van Lieshout, Laura, Barnes, Carmen M., Behmoiras, Liana, Scarpitti, Meghan, Kivaa, Monicah, Duong, Khanh L., Benard, Ludo O., Ellsworth, Jeff L., Avila, Nancy, Faulkner, Deiby, Hayes, April, Lotterhand, Jason, Rivas, Jose Israel, Sengooba, Arnold V., Tzianabos, Alec, Seymour, Albert B., Francone, Omar L.
Publicado 2022