Stressed telomeres without POT1 enhance tumorigenesis

por Sfeir, Agnel, Denchi, Eros Lazzerini
Publicado 2016

Imaging of Telomerase RNA by Single-Molecule Inexpensive FISH Combined with Immunofluorescence

por Querido, Emmanuelle, Sfeir, Agnel, Chartrand, Pascal
Publicado 2020

Quantitative Imaging of MS2-Tagged hTR in Cajal Bodies: Photobleaching and Photoactivation

por Smith, Michael, Querido, Emmanuelle, Chartrand, Pascal, Sfeir, Agnel
Publicado 2020

Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining

por Kent, Tatiana, Mateos-Gomez, Pedro A, Sfeir, Agnel, Pomerantz, Richard T
Publicado 2016

Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore

por Pinzaru, Alexandra M., Kareh, Mike, Lamm, Noa, Lazzerini-Denchi, Eros, Cesare, Anthony J., Sfeir, Agnel
Publicado 2020

Rap1 regulates TIP60 function during fate transition between two-cell-like and pluripotent states

por Barry, Raymond Mario, Sacco, Olivia, Mameri, Amel, Stojaspal, Martin, Kartsonis, William, Shah, Pooja, De Ioannes, Pablo, Hofr, Ctirad, Côté, Jacques, Sfeir, Agnel
Publicado 2022

Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis

por Pinzaru, Alexandra M., Hom, Robert A., Beal, Angela, Phillips, Aaron F., Ni, Eric, Cardozo, Timothy, Nair, Nidhi, Choi, Jaehyuk, Wuttke, Deborah S., Sfeir, Agnel, Denchi, Eros Lazzerini
Publicado 2016

POLQ inhibition elicits an immune response in homologous recombination–deficient pancreatic adenocarcinoma via cGAS/STING signaling

por Oh, Grace, Wang, Annie, Wang, Lidong, Li, Jiufeng, Werba, Gregor, Weissinger, Daniel, Zhao, Ende, Dhara, Surajit, Hernandez, Rosmel E., Ackermann, Amanda, Porcella, Sarina, Kalfakakou, Despoina, Dolgalev, Igor, Kawaler, Emily, Golan, Talia, Welling, Theodore H., Sfeir, Agnel, Simeone, Diane M.
Publicado 2023