Structure-Based Modeling of SARS-CoV-2 Peptide/HLA-A02 Antigens

por Nerli, Santrupti, Sgourakis, Nikolaos G.
Publicado 2020

Editorial: Computational approaches for interpreting experimental data and understanding protein structure, dynamics and function relationships

por Hu, Kaifeng, Lee, Woonghee, Montelione, Gaetano T., Sgourakis, Nikolaos G., Vögeli, Beat
Publicado 2022

A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models

por Sgourakis, Nikolaos G, Bagos, Pantelis G, Papasaikas, Panagiotis K, Hamodrakas, Stavros J
Publicado 2005

Backbone-independent NMR resonance assignments of methyl probes in large proteins

por Nerli, Santrupti, De Paula, Viviane S., McShan, Andrew C., Sgourakis, Nikolaos G.
Publicado 2021

HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes

por Gupta, Sagar, Nerli, Santrupti, Kutti Kandy, Sreeja, Mersky, Glenn L., Sgourakis, Nikolaos G.
Publicado 2023

Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch

por De Paula, Viviane S., Jude, Kevin M., Nerli, Santrupti, Glassman, Caleb R., Garcia, K. Christopher, Sgourakis, Nikolaos G.
Publicado 2020

A Chicken Tapasin ortholog can chaperone empty HLA-B∗37:01 molecules independent of other peptide-loading components

por Papadaki, Georgia F., Woodward, Claire H., Young, Michael C., Winters, Trenton J., Burslem, George M., Sgourakis, Nikolaos G.
Publicado 2023

High-resolution structure of a Shigella type III secretion needle by solid-state NMR and cryo-electron microscopy

por Demers, Jean-Philippe, Habenstein, Birgit, Loquet, Antoine, Vasa, Suresh Kumar, Giller, Karin, Becker, Stefan, Baker, David, Lange, Adam, Sgourakis, Nikolaos G.
Publicado 2014

Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules

por Papadaki, Georgia F., Ani, Omar, Florio, Tyler J., Young, Michael C., Danon, Julia N., Sun, Yi, Dersh, Devin, Sgourakis, Nikolaos G.
Publicado 2023

Determination of the Structures of Symmetric Protein Oligomers from NMR Chemical Shifts and Residual Dipolar Couplings

por Sgourakis, Nikolaos G., Lange, Oliver F., DiMaio, Frank, André, Ingemar, Fitzkee, Nicholas C., Rossi, Paolo, Montelione, Gaetano T., Bax, Ad, Baker, David
Publicado 2011

Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra

por Evangelidis, Thomas, Nerli, Santrupti, Nováček, Jiří, Brereton, Andrew E., Karplus, P. Andrew, Dotas, Rochelle R., Venditti, Vincenzo, Sgourakis, Nikolaos G., Tripsianes, Konstantinos
Publicado 2018

TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap

por McShan, Andrew C., Devlin, Christine A., Morozov, Giora I., Overall, Sarah A., Moschidi, Danai, Akella, Neha, Procko, Erik, Sgourakis, Nikolaos G.
Publicado 2021

The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles

por Demers, Jean-Philippe, Sgourakis, Nikolaos G., Gupta, Rashmi, Loquet, Antoine, Giller, Karin, Riedel, Dietmar, Laube, Britta, Kolbe, Michael, Baker, David, Becker, Stefan, Lange, Adam
Publicado 2013

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling

por Natarajan, Kannan, Jiang, Jiansheng, May, Nathan A., Mage, Michael G., Boyd, Lisa F., McShan, Andrew C., Sgourakis, Nikolaos G., Bax, Ad, Margulies, David H.
Publicado 2018

Nearest-neighbor NMR spectroscopy: categorizing spectral peaks by their adjacent nuclei

por Behera, Soumya P., Dubey, Abhinav, Chen, Wan-Na, De Paula, Viviane S., Zhang, Meng, Sgourakis, Nikolaos G., Bermel, Wolfgang, Wagner, Gerhard, Coote, Paul W., Arthanari, Haribabu
Publicado 2020

Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes

por Sun, Yi, Papadaki, Georgia F., Devlin, Christine A., Danon, Julia N., Young, Michael C., Winters, Trenton J., Burslem, George M., Procko, Erik, Sgourakis, Nikolaos G.
Publicado 2023

Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes

por Sun, Yi, Young, Michael C., Woodward, Claire H., Danon, Julia N., Truong, Hau V., Gupta, Sagar, Winters, Trenton J., Font-Burgada, Joan, Burslem, George M., Sgourakis, Nikolaos G.
Publicado 2023

Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection

por McShan, Andrew C., Devlin, Christine A., Overall, Sarah A., Park, Jihye, Toor, Jugmohit S., Moschidi, Danai, Flores-Solis, David, Choi, Hannah, Tripathi, Sarvind, Procko, Erik, Sgourakis, Nikolaos G.
Publicado 2019

De novo design of a non-local β-sheet protein with high stability and accuracy

por Marcos, Enrique, Chidyausiku, Tamuka M., McShan, Andrew C., Evangelidis, Thomas, Nerli, Santrupti, Carter, Lauren, Nivón, Lucas G., Davis, Audrey, Oberdorfer, Gustav, Tripsianes, Konstantinos, Sgourakis, Nikolaos G., Baker, David
Publicado 2018

An order-to-disorder structural switch activates the FoxM1 transcription factor

por Marceau, Aimee H, Brison, Caileen M, Nerli, Santrupti, Arsenault, Heather E, McShan, Andrew C, Chen, Eefei, Lee, Hsiau-Wei, Benanti, Jennifer A, Sgourakis, Nikolaos G, Rubin, Seth M
Publicado 2019