Live longer on MARS: a yeast paradigm of mitochondrial adaptive ROS signaling in aging

por Shadel, Gerald S.
Publicado 2014

A "radical" mitochondrial view of autophagy-related pathology

por Raimundo, Nuno, Shadel, Gerald S.
Publicado 2009

Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial...

por Pan, Yong, Shadel, Gerald S.
Publicado 2009

Expanding the mitochondrial interactome

por Shutt, Timothy E, Shadel, Gerald S
Publicado 2007

Repression of Mitochondrial Translation, Respiration and a Metabolic Cycle-Regulated Gene, SLF1, by the Yeast Pumilio-Family Protein Puf3p

por Chatenay-Lapointe, Marc, Shadel, Gerald S.
Publicado 2011

Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis

por Surovtseva, Yulia V., Shadel, Gerald S.
Publicado 2013

A Mitochondrial Perspective of Chronic Obstructive Pulmonary Disease Pathogenesis

por Kang, Min-Jong, Shadel, Gerald S.
Publicado 2016

Pink1/Parkin link inflammation, mitochondrial stress, and neurodegeneration

por Newman, Laura E., Shadel, Gerald S.
Publicado 2018

Relative abundance of the human mitochondrial transcription system and distinct roles for h-mtTFB1 and h-mtTFB2 in mitochondrial biogenesis and gene expression

por Cotney, Justin, Wang, Zhibo, Shadel, Gerald S.
Publicado 2007

Impaired Mitochondrial Mobility in Charcot-Marie-Tooth Disease

por Schiavon, Cara R., Shadel, Gerald S., Manor, Uri
Publicado 2021

Transcriptional activation by mitochondrial transcription factor A involves preferential distortion of promoter DNA

por Malarkey, Christopher S., Bestwick, Megan, Kuhlwilm, Jane E., Shadel, Gerald S., Churchill, Mair E. A.
Publicado 2012

Insights into epithelial cell senescence from transcriptome and secretome analysis of human oral keratinocytes

por Schwartz, Rachael E., Shokhirev, Maxim N., Andrade, Leonardo R., Gutkind, J. Silvio, Iglesias-Bartolome, Ramiro, Shadel, Gerald S.
Publicado 2021

Ancient mtDNA Genetic Variants Modulate mtDNA Transcription and Replication

por Suissa, Sarit, Wang, Zhibo, Poole, Jason, Wittkopp, Sharine, Feder, Jeanette, Shutt, Timothy E., Wallace, Douglas C., Shadel, Gerald S., Mishmar, Dan
Publicado 2009

Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence

por Schleicher, Michael, Shepherd, Benjamin R., Suarez, Yajaira, Fernandez-Hernando, Carlos, Yu, Jun, Pan, Yong, Acevedo, Lisette M., Shadel, Gerald S., Sessa, William C.
Publicado 2008

ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

por Hancock-Cerutti, William, Wu, Zheng, Xu, Peng, Yadavalli, Narayana, Leonzino, Marianna, Tharkeshwar, Arun Kumar, Ferguson, Shawn M., Shadel, Gerald S., De Camilli, Pietro
Publicado 2022

TLR signaling augments macrophage bactericidal activity through mitochondrial ROS

por West, A. Phillip, Brodsky, Igor E., Rahner, Christoph, Woo, Dong Kyun, Erdjument-Bromage, Hediye, Tempst, Paul, Walsh, Matthew C., Choi, Yongwon, Shadel, Gerald S., Ghosh, Sankar
Publicado 2011

Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis

por Nassour, Joe, Aguiar, Lucia Gutierrez, Correia, Adriana, Schmidt, Tobias T., Mainz, Laura, Przetocka, Sara, Haggblom, Candy, Tadepalle, Nimesha, Williams, April, Shokhirev, Maxim N., Akincilar, Semih C., Tergaonkar, Vinay, Shadel, Gerald S., Karlseder, Jan
Publicado 2023

Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT

por Al Khatib, Iman, Deng, Jingti, Lei, Yuanjiu, Torres-Odio, Sylvia, Rojas, Gladys R, Newman, Laura E, Chung, Brian K, Symes, Andrew, Zhang, Hongliang, Huang, Shar-yin N, Pommier, Yves, Khan, Aneal, Shadel, Gerald S, West, Andrew Phillip, Gibson, William T, Shutt, Timothy E
Publicado 2023

Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response

por West, A. Phillip, Khoury-Hanold, William, Staron, Matthew, Tal, Michal C., Pineda, Cristiana M., Lang, Sabine M., Bestwick, Megan, Duguay, Brett A., Raimundo, Nuno, MacDuff, Donna A., Kaech, Susan M., Smiley, James R., Means, Robert E., Iwasaki, Akiko, Shadel, Gerald S.
Publicado 2015

Mitochondrial DNA Stress Signalling Protects the Nuclear Genome

por Wu, Zheng, Oeck, Sebastian, West, A. Phillip, Mangalhara, Kailash C., Sainz, Alva G., Newman, Laura E., Zhang, Xiao-Ou, Wu, Lizhen, Yan, Qin, Bosenberg, Marcus, Liu, Yanfeng, Sulkowski, Parker L., Tripple, Victoria, Kaech, Susan M., Glazer, Peter M., Shadel, Gerald S.
Publicado 2019