The Essential Thioredoxin Reductase of the Human Pathogenic Mold Aspergillus fumigatus Is a Promising Antifungal Target

por Binder, Jasmin, Shadkchan, Yana, Osherov, Nir, Krappmann, Sven
Publicado 2020

Siroheme Is Essential for Assimilation of Nitrate and Sulfate as Well as Detoxification of Nitric Oxide but Dispensable for Murine Virulence of Aspergillus fumigatus

por Dietl, Anna-Maria, Binder, Ulrike, Shadkchan, Yana, Osherov, Nir, Haas, Hubertus
Publicado 2018

Arginine Auxotrophy Affects Siderophore Biosynthesis and Attenuates Virulence of Aspergillus fumigatus

por Dietl, Anna-Maria, Binder, Ulrike, Bauer, Ingo, Shadkchan, Yana, Osherov, Nir, Haas, Hubertus
Publicado 2020

PrtT-Regulated Proteins Secreted by Aspergillus fumigatus Activate MAPK Signaling in Exposed A549 Lung Cells Leading to Necrotic Cell Death

por Sharon, Haim, Amar, David, Levdansky, Emma, Mircus, Gabriel, Shadkchan, Yana, Shamir, Ron, Osherov, Nir
Publicado 2011

The leucine biosynthetic pathway is crucial for adaptation to iron starvation and virulence in Aspergillus fumigatus

por Orasch, Thomas, Dietl, Anna-Maria, Shadkchan, Yana, Binder, Ulrike, Bauer, Ingo, Lass-Flörl, Cornelia, Osherov, Nir, Haas, Hubertus
Publicado 2019

Contribution of ATPase copper transporters in animal but not plant virulence of the crossover pathogen Aspergillus flavus

por Yang, Kunlong, Shadkchan, Yana, Tannous, Joanna, Landero Figueroa, Julio A., Wiemann, Philipp, Osherov, Nir, Wang, Shihua, Keller, Nancy P.
Publicado 2018

The Lysine Deacetylase RpdA Is Essential for Virulence in Aspergillus fumigatus

por Bauer, Ingo, Misslinger, Matthias, Shadkchan, Yana, Dietl, Anna-Maria, Petzer, Verena, Orasch, Thomas, Abt, Beate, Graessle, Stefan, Osherov, Nir, Haas, Hubertus
Publicado 2019

Uptake of the Siderophore Triacetylfusarinine C, but Not Fusarinine C, Is Crucial for Virulence of Aspergillus fumigatus

por Aguiar, Mario, Orasch, Thomas, Shadkchan, Yana, Caballero, Patricia, Pfister, Joachim, Sastré-Velásquez, Luis Enrique, Gsaller, Fabio, Decristoforo, Clemens, Osherov, Nir, Haas, Hubertus
Publicado 2022

Phenotypic and Proteomic Analysis of the Aspergillus fumigatus ΔPrtT, ΔXprG and ΔXprG/ΔPrtT Protease-Deficient Mutants

por Shemesh, Einav, Hanf, Benjamin, Hagag, Shelly, Attias, Shani, Shadkchan, Yana, Fichtman, Boris, Harel, Amnon, Krüger, Thomas, Brakhage, Axel A., Kniemeyer, Olaf, Osherov, Nir
Publicado 2017

Transcriptional response of Aspergillus fumigatus to copper and the role of the Cu chaperones

por Anabosi, Duaa, Meir, Zohar, Shadkchan, Yana, Handelman, Mariana, Abou-Kandil, Ammar, Yap, Annie, Urlings, Daniel, Gold, Morgan S., Krappmann, Sven, Haas, Hubertus, Osherov, Nir
Publicado 2021