APE1/Ref‐1 knockdown in pancreatic ductal adenocarcinoma – characterizing gene expression changes and identifying novel pathways using single‐cell RNA sequencing

por Shah, Fenil, Goossens, Emery, Atallah, Nadia M., Grimard, Michelle, Kelley, Mark R., Fishel, Melissa L.
Publicado 2017

Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic

por Shah, Fenil, Logsdon, Derek, Messmann, Richard A., Fehrenbacher, Jill C., Fishel, Melissa L., Kelley, Mark R.
Publicado 2017

The thioredoxin system in breast cancer cell invasion and migration

por Bhatia, Maneet, McGrath, Kelly L., Di Trapani, Giovanna, Charoentong, Pornpimol, Shah, Fenil, King, Mallory M., Clarke, Frank M., Tonissen, Kathryn F.
Publicado 2015

The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2

por Swuec, Paolo, Renault, Ludovic, Borg, Aaron, Shah, Fenil, Murphy, Vincent J., van Twest, Sylvie, Snijders, Ambrosius P., Deans, Andrew J., Costa, Alessandro
Publicado 2016

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

por Logsdon, Derek P., Shah, Fenil, Carta, Fabrizio, Supuran, Claudiu T., Kamocka, Malgorzata, Jacobsen, Max H., Sandusky, George E., Kelley, Mark R., Fishel, Melissa L.
Publicado 2018

LTMG: a novel statistical modeling of transcriptional expression states in single-cell RNA-Seq data

por Wan, Changlin, Chang, Wennan, Zhang, Yu, Shah, Fenil, Lu, Xiaoyu, Zang, Yong, Zhang, Anru, Cao, Sha, Fishel, Melissa L, Ma, Qin, Zhang, Chi
Publicado 2019

The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

por Schwab, Rebekka A., Nieminuszczy, Jadwiga, Shah, Fenil, Langton, Jamie, Lopez Martinez, David, Liang, Chih-Chao, Cohn, Martin A., Gibbons, Richard J., Deans, Andrew J., Niedzwiedz, Wojciech
Publicado 2015

Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target

por Gampala, Silpa, Shah, Fenil, Lu, Xiaoyu, Moon, Hye-ran, Babb, Olivia, Umesh Ganesh, Nikkitha, Sandusky, George, Hulsey, Emily, Armstrong, Lee, Mosely, Amber L., Han, Bumsoo, Ivan, Mircea, Yeh, Jing-Ruey Joanna, Kelley, Mark R., Zhang, Chi, Fishel, Melissa L.
Publicado 2021

Combined inhibition of Ref‐1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co‐culture models

por Caston, Rachel A., Shah, Fenil, Starcher, Colton L., Wireman, Randall, Babb, Olivia, Grimard, Michelle, McGeown, Jack, Armstrong, Lee, Tong, Yan, Pili, Roberto, Rupert, Joseph, Zimmers, Teresa A., Elmi, Adily N., Pollok, Karen E., Motea, Edward A., Kelley, Mark R., Fishel, Melissa L.
Publicado 2020

Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

por Gampala, Silpa, Shah, Fenil, Zhang, Chi, Rhodes, Steven D., Babb, Olivia, Grimard, Michelle, Wireman, Randall S., Rad, Ellie, Calver, Brian, Bai, Ren-Yuan, Staedtke, Verena, Hulsey, Emily L., Saadatzadeh, M. Reza, Pollok, Karen E., Tong, Yan, Smith, Abbi E., Clapp, D. Wade, Tee, Andrew R., Kelley, Mark R., Fishel, Melissa L.
Publicado 2021

Correction: Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

por Gampala, Silpa, Shah, Fenil, Zhang, Chi, Rhodes, Steven D., Babb, Olivia, Grimard, Michelle, Wireman, Randall S., Rad, Ellie, Calver, Brian, Bai, Ren-Yuan, Staedtke, Verena, Hulsey, Emily L., Saadatzadeh, M. Reza, Pollok, Karen E., Tong, Yan, Smith, Abbi E., Clapp, D. Wade, Tee, Andrew R., Kelley, Mark R., Fishel, Melissa L.
Publicado 2022