Integration of multiple biological contexts reveals principles of synthetic lethality that affect reproducibility

por Ku, Angel A., Hu, Hsien-Ming, Zhao, Xin, Shah, Khyati N., Kongara, Sameera, Wu, Di, McCormick, Frank, Balmain, Allan, Bandyopadhyay, Sourav
Publicado 2020

A Quantitative Chemotherapy Genetic Interaction Map Reveals Factors Associated with PARP Inhibitor Resistance

por Hu, Hsien-Ming, Zhao, Xin, Kaushik, Swati, Robillard, Lilliane, Barthelet, Antoine, Lin, Kevin K., Shah, Khyati N., Simmons, Andy D., Raponi, Mitch, Harding, Thomas C., Bandyopadhyay, Sourav
Publicado 2018

Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer

por Donnella, Hayley J, Webber, James T, Levin, Rebecca S, Camarda, Roman, Momcilovic, Olga, Bayani, Nora, Shah, Khyati N, Korkola, James, Shokat, Kevan M, Goga, Andrei, Gordan, John D, Bandyopadhyay, Sourav
Publicado 2018

Aurora kinase A drives the evolution of resistance to third generation EGFR inhibitors in lung cancer

por Shah, Khyati N., Bhatt, Roma, Rotow, Julia, Rohrberg, Julia, Olivas, Victor, Wang, Victoria E., Hemmati, Golzar, Martins, Maria M., Maynard, Ashley, Kuhn, Jonathan, Galeas, Jacqueline, Donnella, Hayley J., Kaushik, Swati, Ku, Angel, Dumont, Sophie, Krings, Gregor, Haringsma, Henry J., Robillard, Liliane, Simmons, Andrew D., Harding, Thomas C., McCormick, Frank, Goga, Andrei, Blakely, Collin M., Bivona, Trever G., Bandyopadhyay, Sourav
Publicado 2018