Complex Genomic Rearrangements Involving ETV6::ABL1 Gene Fusion in an Individual with Myeloid Neoplasm

por Qi, Zhongxia, Smith, Catherine, Shah, Neil P., Yu, Jingwei
Publicado 2023

FLT3 D835 Mutations Confer Differential Resistance to Type II FLT3 Inhibitors

por Smith, Catherine C., Lin, Kimberly, Stecula, Adrian, Sali, Andrej, Shah, Neil P.
Publicado 2015

Differential effects of dosing regimen on the safety and efficacy of dasatinib: retrospective exposure–response analysis of a Phase III study

por Wang, Xiaoning, Roy, Amit, Hochhaus, Andreas, Kantarjian, Hagop M, Chen, Tai-Tsang, Shah, Neil P
Publicado 2013

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells

por Metts, Jonathan, Bradley, Heath L., Wang, Zhengqi, Shah, Neil P., Kapur, Reuben, Arbiser, Jack L., Bunting, Kevin D.
Publicado 2017

Elbow Evaluation Via Telephone and Video Visit

por Vomer, Rock P, Carfagno, David, Lewno, Adam, Shah, Neil P, Farford, Bryan A, Kieneker, Lisa, Pujalte, George G. A
Publicado 2023

Lymphocytosis after treatment with dasatinib in chronic myeloid leukemia: Effects on response and toxicity

por Schiffer, Charles A., Cortes, Jorge E., Hochhaus, Andreas, Saglio, Giuseppe, le Coutre, Philipp, Porkka, Kimmo, Mustjoki, Satu, Mohamed, Hesham, Shah, Neil P.
Publicado 2016

Telemedicine Evaluation of Hip Ailments

por Vomer, Rock P, York, Emma, DeMatas, Kristina, Shah, Neil P, Larick, Rayghan S, Punj, Mantavya, Rosario-Concepcion, Raul A, Pujalte, George G. A
Publicado 2023

Evaluation of cardiovascular ischemic event rates in dasatinib-treated patients using standardized incidence ratios

por Saglio, Giuseppe, le Coutre, Philipp, Cortes, Jorge, Mayer, Jiří, Rowlings, Philip, Mahon, François-Xavier, Kroog, Glenn, Gooden, Kyna, Subar, Milayna, Shah, Neil P.
Publicado 2017

Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT

por Bharate, Jaideep B., McConnell, Nicholas, Naresh, Gunaganti, Zhang, Lingtian, Lakkaniga, Naga Rajiv, Ding, Lucky, Shah, Neil P., Frett, Brendan, Li, Hong-yu
Publicado 2018

Dasatinib in imatinib‐resistant or ‐intolerant chronic‐phase, chronic myeloid leukemia patients: 7‐year follow‐up of study CA180‐034

por Shah, Neil P., Rousselot, Philippe, Schiffer, Charles, Rea, Delphine, Cortes, Jorge E., Milone, Jorge, Mohamed, Hesham, Healey, Diane, Kantarjian, Hagop, Hochhaus, Andreas, Saglio, Giuseppe
Publicado 2016

Overcoming myelosuppression due to synthetic lethal toxicity for FLT3-targeted acute myeloid leukemia therapy

por Warkentin, Alexander A, Lopez, Michael S, Lasater, Elisabeth A, Lin, Kimberly, He, Bai-Liang, Leung, Anskar YH, Smith, Catherine C, Shah, Neil P, Shokat, Kevan M
Publicado 2014

Targeting substrate-site in Jak2 kinase prevents emergence of genetic resistance

por Kesarwani, Meenu, Huber, Erika, Kincaid, Zachary, Evelyn, Chris R., Biesiada, Jacek, Rance, Mark, Thapa, Mahendra B., Shah, Neil P., Meller, Jarek, Zheng, Yi, Azam, Mohammad
Publicado 2015

Incidence, outcomes, and risk factors of pleural effusion in patients receiving dasatinib therapy for Philadelphia chromosome-positive leukemia

por Hughes, Timothy P., Laneuville, Pierre, Rousselot, Philippe, Snyder, David S., Rea, Delphine, Shah, Neil P., Paar, David, Abruzzese, Elisabetta, Hochhaus, Andreas, Lipton, Jeffrey H., Cortes, Jorge E.
Publicado 2019

Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models

por Mali, Raghuveer Singh, Zhang, Qi, DeFilippis, Rosa Anna, Cavazos, Antonio, Kuruvilla, Vinitha Mary, Raman, Jayant, Mody, Vidhi, Choo, Edna F., Dail, Monique, Shah, Neil P., Konopleva, Marina, Sampath, Deepak, Lasater, Elisabeth A.
Publicado 2020

Analysis of the potential effect of ponatinib on the QTc interval in patients with refractory hematological malignancies

por Sonnichsen, Daryl, Dorer, David J., Cortes, Jorge, Talpaz, Moshe, Deininger, Michael W., Shah, Neil P., Kantarjian, Hagop M., Bixby, Dale, Mauro, Michael J., Flinn, Ian W., Litwin, Jeffrey, Turner, Christopher D., Haluska, Frank G.
Publicado 2013

P670: EARLY CYTOGENETIC OR MOLECULAR LANDMARK RESPONSE TO PONATINIB TREATMENT PREDICTS OUTCOMES IN HEAVILY PRETREATED PATIENTS WITH CHRONIC-PHASE CHRONIC MYELOID LEUKEMIA IN PACE:...

por Müller, Martin C., Cortes, Jorge, Chuah, Charles, Deangelo, Daniel, Deininger, Michael, Guilhot, François, Hughes, Timothy, Emmanuel Nicolini, Franck, Pinilla-Ibarz, Javier, Rea, Delphine, Rosti, Gianantonio, Shah, Neil P., Talpaz, Moshe, Lu, Vickie, Padukkavidana, Thihan, Kantarjian, Hagop
Publicado 2023

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology

por Ciceri, Pietro, Müller, Susanne, O’Mahony, Alison, Fedorov, Oleg, Filippakopoulos, Panagis, Hunt, Jeremy P., Lasater, Elisabeth A., Pallares, Gabriel, Picaud, Sarah, Wells, Christopher, Martin, Sarah, Wodicka, Lisa M., Shah, Neil P., Treiber, Daniel K., Knapp, Stefan
Publicado 2014

The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment

por Tran, Thai Hoa, Nguyen, Jonathan V., Stecula, Adrian, Akutagawa, Jon, Moorman, Anthony V., Braun, Benjamin S., Sali, Andrej, Mullighan, Charles G., Shah, Neil P., Dai, Yunfeng, Devidas, Meenakshi, Roberts, Kathryn G., Smith, Catherine C., Loh, Mignon L.
Publicado 2021

Patient- and physician-reported pain after tyrosine kinase inhibitor discontinuation among patients with chronic myeloid leukemia

por Flynn, Kathryn E., Atallah, Ehab, Lin, Li, Shah, Neil P., Silver, Richard T., Larson, Richard A., Pinilla-Ibarz, Javier, Thompson, James E., Oehler, Vivian G., Radich, Jerald P., Kota, Vamsi, Mauro, Michael J., Schiffer, Charles A., Cortes, Jorge, Weinfurt, Kevin P.
Publicado 2022

BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia

por Hurtz, Christian, Hatzi, Katerina, Cerchietti, Leandro, Braig, Melanie, Park, Eugene, Kim, Yong-mi, Herzog, Sebastian, Ramezani-Rad, Parham, Jumaa, Hassan, Müller, Martin C., Hofmann, Wolf-Karsten, Hochhaus, Andreas, Ye, B. Hilda, Agarwal, Anupriya, Druker, Brian J., Shah, Neil P., Melnick, Ari M., Müschen, Markus
Publicado 2011