Vaccination with post-translational modified, homocitrullinated peptides induces CD8 T-cell responses that mediate antitumor immunity

por Shah, Sabaria, Cook, Katherine W, Symonds, Peter, Weißer, Juliane, Skinner, Anne, Al Omari, Abdullah, Paston, Samantha J, Pike, Ian, Durrant, Lindy G, Brentville, Victoria A
Publicado 2023

T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; Targeting of citrullinated self-peptides presented by HLA-DP4 for tumou...

por Brentville, Victoria A, Symonds, Peter, Cook, Katherine W, Daniels, Ian, Pitt, Tracy, Gijon, Mohamed, Vaghela, Poonam, Xue, Wei, Shah, Sabaria, Metheringham, Rachael L, Durrant, Lindy G
Publicado 2019

Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity

por Cook, Katherine, Xue, Wei, Atabani, Suha, Symonds, Peter, Al Omari, Abdullah, Daniels, Ian, Shah, Sabaria, Choudhury, Ruhul Hasan, Weston, Daisy, Metheringham, Rachael, Brentville, Victoria, Durrant, Lindy
Publicado 2022

Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation

por Malecka, Anna, Wang, Qunwei, Shah, Sabaria, Sutavani, Ruhcha V., Spendlove, Ian, Ramage, Judith M., Greensmith, Julie, Franks, Hester A., Gough, Michael J., Saalbach, Anja, Patel, Poulam M., Jackson, Andrew M.
Publicado 2016

Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy

por Brentville, Victoria Anne, Symonds, Peter, Chua, JiaXin, Skinner, Anne, Daniels, Ian, Cook, Katherine Wendy, Koncarevic, Sasa, Martinez-Pinna, Roxana, Shah, Sabaria, Choudhury, Ruhul Hasan, Vaghela, Poonam, Weston, Daisy, Al-Omari, Abdullah, Davis, James, Durrant, Lindy G.
Publicado 2022

Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in the tumor environment is a target for cancer immunotherapy

por Cook, Katherine W, Xue, Wei, Symonds, Peter, Daniels, Ian, Gijon, Mohamed, Boocock, David, Coveney, Clare, Miles, Amanda K, Shah, Sabaria, Atabani, Suha, Choudhury, Ruhul H, Vaghela, Poonam, Weston, Daisy, Metheringham, Rachael L, Brentville, Victoria A, Durrant, Lindy G
Publicado 2021