Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute

por Cooper, Chris E., Silkstone, Gary G.A., Simons, Michelle, Rajagopal, Badri, Syrett, Natalie, Shaik, Thoufieq, Gretton, Svetlana, Welbourn, Elizabeth, Bülow, Leif, Eriksson, Nélida Leiva, Ronda, Luca, Mozzarelli, Andrea, Eke, Andras, Mathe, Domokos, Reeder, Brandon J.
Publicado 2019

Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers

por Simons, Michelle, Gretton, Svetlana, Silkstone, Gary G.A., Rajagopal, Badri S., Allen-Baume, Victoria, Syrett, Natalie, Shaik, Thoufieq, Leiva-Eriksson, Nelida, Ronda, Luca, Mozzarelli, Andrea, Strader, Michael B., Alayash, Abdu I., Reeder, Brandon J., Cooper, Chris E.
Publicado 2018