The small molecule dispergo tubulates the endoplasmic reticulum and inhibits export

por Lu, Lei, Hannoush, Rami N., Goess, Brian C., Varadarajan, Shankar, Shair, Matthew D., Kirchhausen, Tom
Publicado 2013

Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation

por Nitulescu, Ioana I., Meyer, Sara C., Wen, Qiang Jeremy, Crispino, John D., Lemieux, Madeleine E., Levine, Ross L., Pelish, Henry E., Shair, Matthew D.
Publicado 2017

NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations

por Drilon, Alexander, Horan, Joshua C., Tangpeerachaikul, Anupong, Besse, Benjamin, Ou, Sai-Hong Ignatius, Gadgeel, Shirish M., Camidge, D. Ross, van der Wekken, Anthonie J., Nguyen-Phuong, Linh, Acker, Adam, Keddy, Clare, Nicholson, Katelyn S., Yoda, Satoshi, Mente, Scot, Sun, Yuting, Soglia, John R., Kohl, Nancy E., Porter, James R., Shair, Matthew D., Zhu, Viola, Davare, Monika A., Hata, Aaron N., Pelish, Henry E., Lin, Jessica J.
Publicado 2023

Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein

por Strating, Jeroen R.P.M., van der Linden, Lonneke, Albulescu, Lucian, Bigay, Joëlle, Arita, Minetaro, Delang, Leen, Leyssen, Pieter, van der Schaar, Hilde M., Lanke, Kjerstin H.W., Thibaut, Hendrik Jan, Ulferts, Rachel, Drin, Guillaume, Schlinck, Nina, Wubbolts, Richard W., Sever, Navdar, Head, Sarah A., Liu, Jun O., Beachy, Philip A., De Matteis, Maria A., Shair, Matthew D., Olkkonen, Vesa M., Neyts, Johan, van Kuppeveld, Frank J.M.
Publicado 2015

Mediator Kinase Inhibition Further Activates Super-Enhancer Associated Genes in AML

por Pelish, Henry E., Liau, Brian B., Nitulescu, Ioana I., Tangpeerachaikul, Anupong, Poss, Zachary C., Da Silva, Diogo H., Caruso, Brittany T., Arefolov, Alexander, Fadeyi, Olugbeminiyi, Christie, Amanda L., Du, Karrie, Banka, Deepti, Schneider, Elisabeth V., Jestel, Anja, Zou, Ge, Si, Chong, Ebmeier, Christopher C., Bronson, Roderick T., Krivtsov, Andrei V., Myers, Andrew G., Kohl, Nancy E., Kung, Andrew L., Armstrong, Scott A., Lemieux, Madeleine E., Taatjes, Dylan J., Shair, Matthew D.
Publicado 2015