Single-cell analyses to tailor treatments

por Shalek, Alex K., Benson, Mikael
Publicado 2017

Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics

por Wadsworth, Marc H., Hughes, Travis K., Shalek, Alex K.
Publicado 2015

Identification of a Master Regulator of Differentiation in Toxoplasma

por Waldman, Benjamin S., Schwarz, Dominic, Wadsworth, Marc H., Saeij, Jeroen P., Shalek, Alex K., Lourido, Sebastian
Publicado 2020

Improved haplotype inference by exploiting long-range linking and allelic imbalance in RNA-seq datasets

por Berger, Emily, Yorukoglu, Deniz, Zhang, Lillian, Nyquist, Sarah K., Shalek, Alex K., Kellis, Manolis, Numanagić, Ibrahim, Berger, Bonnie
Publicado 2020

Single-cell transcriptomics of staged oocytes and somatic cells reveal novel regulators of follicle activation

por Chen, Yu-Ying, Russo, Daniela D, Drake, Riley S, Duncan, Francesca E, Shalek, Alex K, Goods, Brittany A, Woodruff, Teresa K
Publicado 2022

Seq-Well: A Portable, Low-Cost Platform for High-Throughput Single-Cell RNA-Seq of Low-Input Samples

por Gierahn, Todd M., Wadsworth, Marc H., Hughes, Travis K., Bryson, Bryan D., Butler, Andrew, Satija, Rahul, Fortune, Sarah, Love, J. Christopher, Shalek, Alex K.
Publicado 2017

Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies

por Martin-Gayo, Enrique, Gao, Ce, Chen, Hsiao Rong, Ouyang, Zhengyu, Kim, Dhohyung, Kolb, Kellie E., Shalek, Alex K., Walker, Bruce D., Lichterfeld, Mathias, Yu, Xu G.
Publicado 2020

Identification and Tracking of Alloreactive T Cell Clones in Rhesus Macaques Through the RM-scTCR-Seq Platform

por Gerdemann, Ulrike, Fleming, Ryan A., Kaminski, James, McGuckin, Connor, Rui, Xianliang, Lane, Jennifer F., Keskula, Paula, Cagnin, Lorenzo, Shalek, Alex K., Tkachev, Victor, Kean, Leslie S.
Publicado 2022

Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

por Zhivaki, Dania, Borriello, Francesco, Chow, Ohn A., Doran, Benjamin, Fleming, Ira, Theisen, Derek J., Pallis, Paris, Shalek, Alex K., Sokol, Caroline L., Zanoni, Ivan, Kagan, Jonathan C.
Publicado 2020

Single-Cell RNA Sequencing Reveals That Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress

por Salazar-Martín, Antonio G., Kalluri, Aditya S., Villanueva, Martin A., Hughes, Travis K., Wadsworth, Marc H., Dao, Tyler T., Balcells, Mercedes, Nezami, Farhad R., Shalek, Alex K., Edelman, Elazer R.
Publicado 2023

Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses

por Douam, Florian, Ziegler, Carly G. K., Hrebikova, Gabriela, Fant, Bruno, Leach, Robert, Parsons, Lance, Wang, Wei, Gaska, Jenna M., Winer, Benjamin Y., Heller, Brigitte, Shalek, Alex K., Ploss, Alexander
Publicado 2018

Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration

por Menon, Madhvi, Mohammadi, Shahin, Davila-Velderrain, Jose, Goods, Brittany A., Cadwell, Tanina D., Xing, Yu, Stemmer-Rachamimov, Anat, Shalek, Alex K., Love, John Christopher, Kellis, Manolis, Hafler, Brian P.
Publicado 2019

Functional compensation precedes recovery of tissue mass following acute liver injury

por Walesky, Chad M., Kolb, Kellie E., Winston, Carolyn L., Henderson, Jake, Kruft, Benjamin, Fleming, Ira, Ko, Sungjin, Monga, Satdarshan P., Mueller, Florian, Apte, Udayan, Shalek, Alex K., Goessling, Wolfram
Publicado 2020

MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data

por Finak, Greg, McDavid, Andrew, Yajima, Masanao, Deng, Jingyuan, Gersuk, Vivian, Shalek, Alex K., Slichter, Chloe K., Miller, Hannah W., McElrath, M. Juliana, Prlic, Martin, Linsley, Peter S., Gottardo, Raphael
Publicado 2015

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

por Genshaft, Alex S, Li, Shuqiang, Gallant, Caroline J., Darmanis, Spyros, Prakadan, Sanjay M., Ziegler, Carly G. K., Lundberg, Martin, Fredriksson, Simon, Hong, Joyce, Regev, Aviv, Livak, Kenneth J., Landegren, Ulf, Shalek, Alex K.
Publicado 2016

A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

por Martin-Gayo, Enrique, Cole, Michael B., Kolb, Kellie E., Ouyang, Zhengyu, Cronin, Jacqueline, Kazer, Samuel W., Ordovas-Montanes, Jose, Lichterfeld, Mathias, Walker, Bruce D., Yosef, Nir, Shalek, Alex K., Yu, Xu G.
Publicado 2018

Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells

por Jiang, Ruoyi, Meng, Hailong, Raddassi, Khadir, Fleming, Ira, Hoehn, Kenneth B., Dardick, Kenneth R., Belperron, Alexia A., Montgomery, Ruth R., Shalek, Alex K., Hafler, David A., Kleinstein, Steven H., Bockenstedt, Linda K.
Publicado 2021

A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages

por Kimmerling, Robert J., Lee Szeto, Gregory, Li, Jennifer W., Genshaft, Alex S., Kazer, Samuel W., Payer, Kristofor R., de Riba Borrajo, Jacob, Blainey, Paul C., Irvine, Darrell J., Shalek, Alex K., Manalis, Scott R.
Publicado 2016

Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells

por Pae, Juhee, Ersching, Jonatan, Castro, Tiago B.R., Schips, Marta, Mesin, Luka, Allon, Samuel J., Ordovas-Montanes, Jose, Mlynarczyk, Coraline, Melnick, Ari, Efeyan, Alejo, Shalek, Alex K., Meyer-Hermann, Michael, Victora, Gabriel D.
Publicado 2020

Cellular and transcriptional diversity over the course of human lactation

por Nyquist, Sarah K., Gao, Patricia, Haining, Tessa K. J., Retchin, Michael R., Golan, Yarden, Drake, Riley S., Kolb, Kellie, Mead, Benjamin E., Ahituv, Nadav, Martinez, Micaela E., Shalek, Alex K., Berger, Bonnie, Goods, Brittany A.
Publicado 2022