Transcriptome Kinetics Is Governed by a Genome-Wide Coupling of mRNA Production and Degradation: A Role for RNA Pol II

por Shalem, Ophir, Groisman, Bella, Choder, Mordechai, Dahan, Orna, Pilpel, Yitzhak
Publicado 2011

Correction: Transcriptome Kinetics Is Governed by a Genome-Wide Coupling of mRNA Production and Degradation: A Role for RNA Pol II

por Shalem, Ophir, Groisman, Bella, Choder, Mordechai, Dahan, Orna, Pilpel, Yitzhak
Publicado 2011

Widespread promoter-mediated coordination of transcription and mRNA degradation

por Dori-Bachash, Mally, Shalem, Ophir, Manor, Yair S, Pilpel, Yitzhak, Tirosh, Itay
Publicado 2012

Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics

por Serebrenik, Yevgeniy V., Mani, Deepak, Maujean, Timothé, Burslem, George M., Shalem, Ophir
Publicado 2023

Efficient and flexible tagging of endogenous genes by homology-independent intron targeting

por Serebrenik, Yevgeniy V., Sansbury, Stephanie E., Kumar, Saranya Santhosh, Henao-Mejia, Jorge, Shalem, Ophir
Publicado 2019

Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation

por Shalem, Ophir, Dahan, Orna, Levo, Michal, Martinez, Maria Rodriguez, Furman, Itay, Segal, Eran, Pilpel, Yitzhak
Publicado 2008

Systematic Dissection of the Sequence Determinants of Gene 3’ End Mediated Expression Control

por Shalem, Ophir, Sharon, Eilon, Lubliner, Shai, Regev, Ifat, Lotan-Pompan, Maya, Yakhini, Zohar, Segal, Eran
Publicado 2015

Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins

por Viera Ortiz, Ashley P, Cajka, Gregory, Olatunji, Olamide A, Mikytuck, Bailey, Shalem, Ophir, Lee, Edward B
Publicado 2022

Measurements of the Impact of 3′ End Sequences on Gene Expression Reveal Wide Range and Sequence Dependent Effects

por Shalem, Ophir, Carey, Lucas, Zeevi, Danny, Sharon, Eilon, Keren, Leeat, Weinberger, Adina, Dahan, Orna, Pilpel, Yitzhak, Segal, Eran
Publicado 2013

In vivo genome editing using Staphylococcus aureus Cas9

por Ran, F. Ann, Cong, Le, Yan, Winston X., Scott, David A., Gootenberg, Jonathan S., Kriz, Andrea J., Zetsche, Bernd, Shalem, Ophir, Wu, Xuebing, Makarova, Kira S., Koonin, Eugene, Sharp, Phillip A., Zhang, Feng
Publicado 2015

Large‐scale genetic screens identify BET‐1 as a cytoskeleton regulator promoting actin function and life span

por Garcia, Gilberto, Bar‐Ziv, Raz, Averbukh, Maxim, Dasgupta, Nirmalya, Dutta, Naibedya, Zhang, Hanlin, Fan, Wudi, Moaddeli, Darius, Tsui, C. Kimberly, Castro Torres, Toni, Alcala, Athena, Moehle, Erica A., Hoang, Sally, Shalem, Ophir, Adams, Peter D., Thorwald, Max A., Higuchi‐Sanabria, Ryo
Publicado 2022

High density SNP array and reanalysis of genome sequencing uncovers CNVs associated with neurodevelopmental disorders in KOLF2.1J iPSCs

por Gracia-Diaz, Carolina, Perdomo, Jonathan E., Khan, Munir E., Disanza, Brianna, Cajka, Gregory G., Lei, Sunyimeng, Gagne, Alyssa, Maguire, Jean Ann, Roule, Thomas, Shalem, Ophir, Bhoj, Elizabeth J., Ahrens-Nicklas, Rebecca C., French, Deborah, Goldberg, Ethan M., Wang, Kai, Glessner, Joseph, Akizu, Naiara
Publicado 2023

Therapeutic genetic variation revealed in diverse Hsp104 homologs

por March, Zachary M, Sweeney, Katelyn, Kim, Hanna, Yan, Xiaohui, Castellano, Laura M, Jackrel, Meredith E, Lin, JiaBei, Chuang, Edward, Gomes, Edward, Willicott, Corey W, Michalska, Karolina, Jedrzejczak, Robert P, Joachimiak, Andrzej, Caldwell, Kim A, Caldwell, Guy A, Shalem, Ophir, Shorter, James
Publicado 2020

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

por Canver, Matthew C., Smith, Elenoe C., Sher, Falak, Pinello, Luca, Sanjana, Neville E., Shalem, Ophir, Chen, Diane D., Schupp, Patrick G., Vinjamur, Divya S., Garcia, Sara P., Luc, Sidinh, Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Maeda, Takahiro, Yuan, Guo-Cheng, Feng, Zhang, Orkin, Stuart H., Bauer, Daniel E.
Publicado 2015

Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization

por Moehle, Erica A., Higuchi-Sanabria, Ryo, Tsui, C. Kimberly, Homentcovschi, Stefan, Tharp, Kevin M., Zhang, Hanlin, Chi, Hannah, Joe, Larry, de los Rios Rogers, Mattias, Sahay, Arushi, Kelet, Naame, Benitez, Camila, Bar-Ziv, Raz, Garcia, Gilberto, Shen, Koning, Frankino, Phillip A., Schinzel, Robert T., Shalem, Ophir, Dillin, Andrew
Publicado 2021

Transcription control by the ENL YEATS domain in acute leukemia

por Erb, Michael A., Scott, Thomas G., Li, Bin E., Xie, Huafeng, Paulk, Joshiawa, Seo, Hyuk-Soo, Souza, Amanda, Roberts, Justin M., Dastjerdi, Shiva, Buckley, Dennis L., Sanjana, Neville E., Shalem, Ophir, Nabet, Behnam, Zeid, Rhamy, Offei-Addo, Nana K., Dhe-Paganon, Sirano, Zhang, Feng, Orkin, Stuart H., Winter, Georg E., Bradner, James E.
Publicado 2017

Population-scale Longitudinal Mapping of COVID-19 Symptoms, Behavior, and Testing

por Allen, William E., Altae-Tran, Han, Briggs, James, Jin, Xin, McGee, Glen, Shi, Andy, Raghavan, Rumya, Kamariza, Mireille, Nova, Nicole, Pereta, Albert, Danford, Chris, Kamel, Amine, Gothe, Patrik, Milam, Evrhet, Aurambault, Jean, Primke, Thorben, Li, Weijie, Inkenbrandt, Josh, Huynh, Tuan, Chen, Evan, Lee, Christina, Croatto, Michael, Bentley, Helen, Lu, Wendy, Murray, Robert, Travassos, Mark, Coull, Brent A., Openshaw, John, Greene, Casey S., Shalem, Ophir, King, Gary, Probasco, Ryan, Cheng, David R., Silbermann, Ben, Zhang, Feng, Lin, Xihong
Publicado 2020

Publisher Correction: Building an international consortium for tracking coronavirus health status

por Segal, Eran, Zhang, Feng, Lin, Xihong, King, Gary, Shalem, Ophir, Shilo, Smadar, Allen, William E., Alquaddoomi, Faisal, Altae-Tran, Han, Anders, Simon, Balicer, Ran, Bauman, Tal, Bonilla, Ximena, Booman, Gisel, Chan, Andrew T., Cohen, Ori, Coletti, Silvano, Davidson, Natalie, Dor, Yuval, Drew, David A., Elemento, Olivier, Evans, Georgina, Ewels, Phil, Gale, Joshua, Gavrieli, Amir, Geiger, Benjamin, Grad, Yonatan H., Greene, Casey S., Hajirasouliha, Iman, Jerala, Roman, Kahles, Andre, Kallioniemi, Olli, Keshet, Ayya, Kocarev, Ljupco, Landua, Gregory, Meir, Tomer, Muller, Aline, Nguyen, Long H., Oresic, Matej, Ovchinnikova, Svetlana, Peterson, Hedi, Prodanova, Jana, Rajagopal, Jay, Rätsch, Gunnar, Rossman, Hagai, Rung, Johan, Sboner, Andrea, Sigaras, Alexandros, Spector, Tim, Steinherz, Ron, Stevens, Irene, Vilo, Jaak, Wilmes, Paul
Publicado 2020