A selectivity filter mutation provides insights into gating regulation of a K(+) channel

por Friesacher, Theres, Reddy, Haritha P., Bernsteiner, Harald, Carlo Combista, J., Shalomov, Boris, Bera, Amal K., Zangerl-Plessl, Eva-Maria, Dascal, Nathan, Stary-Weinzinger, Anna
Publicado 2022

A novel small-molecule selective activator of homomeric GIRK4 channels

por Cui, Meng, Xu, Keman, Gada, Kirin D., Shalomov, Boris, Ban, Michelle, Eptaminitaki, Giasemi C., Kawano, Takeharu, Plant, Leigh D., Dascal, Nathan, Logothetis, Diomedes E.
Publicado 2022

Encephalopathy-causing mutations in Gβ(1) (GNB1) alter regulation of neuronal GIRK channels

por Reddy, Haritha P., Yakubovich, Daniel, Keren-Raifman, Tal, Tabak, Galit, Tsemakhovich, Vladimir A., Pedersen, Maria H., Shalomov, Boris, Colombo, Sophie, Goldstein, David B., Javitch, Jonathan A., Bera, Amal K., Dascal, Nathan
Publicado 2021

Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor

por Colombo, Sophie, Reddy, Haritha P., Petri, Sabrina, Williams, Damian J., Shalomov, Boris, Dhindsa, Ryan S., Gelfman, Sahar, Krizay, Daniel, Bera, Amal K., Yang, Mu, Peng, Yueqing, Makinson, Christopher D., Boland, Michael J., Frankel, Wayne N., Goldstein, David B., Dascal, Nathan
Publicado 2023