Phosphorylation of the IDP KID Modulates Affinity for KIX by Increasing the Lifetime of the Complex

por Dahal, Liza, Shammas, Sarah L., Clarke, Jane
Publicado 2017

Remarkably Fast Coupled Folding and Binding of the Intrinsically Disordered Transactivation Domain of cMyb to CBP KIX

por Shammas, Sarah L., Travis, Alexandra J., Clarke, Jane
Publicado 2013

Role of non-native electrostatic interactions in the coupled folding and binding of PUMA with Mcl-1

por Chu, Wen-Ting, Clarke, Jane, Shammas, Sarah L., Wang, Jin
Publicado 2017

pKID Binds to KIX via an Unstructured Transition State with Nonnative Interactions

por Dahal, Liza, Kwan, Tristan O.C., Shammas, Sarah L., Clarke, Jane
Publicado 2017

Protein Folding: Adding a Nucleus to Guide Helix Docking Reduces Landscape Roughness

por Wensley, Beth G., Kwa, Lee Gyan, Shammas, Sarah L., Rogers, Joseph M., Clarke, Jane
Publicado 2012

Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies

por Shammas, Sarah L., Crabtree, Michael D., Dahal, Liza, Wicky, Basile I. M., Clarke, Jane
Publicado 2016

Mechanism of Assembly of the Non-Covalent Spectrin Tetramerization Domain from Intrinsically Disordered Partners

por Hill, Stephanie A., Kwa, Lee Gyan, Shammas, Sarah L., Lee, Jennifer C., Clarke, Jane
Publicado 2014

Conserved Helix-Flanking Prolines Modulate Intrinsically Disordered Protein:Target Affinity by Altering the Lifetime of the Bound Complex

por Crabtree, Michael D., Borcherds, Wade, Poosapati, Anusha, Shammas, Sarah L., Daughdrill, Gary W., Clarke, Jane
Publicado 2017

Two Differential Binding Mechanisms of FG-Nucleoporins and Nuclear Transport Receptors

por Tan, Piau Siong, Aramburu, Iker Valle, Mercadante, Davide, Tyagi, Swati, Chowdhury, Aritra, Spitz, Daniel, Shammas, Sarah L., Gräter, Frauke, Lemke, Edward A.
Publicado 2018

Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity

por Kundel, Franziska, De, Suman, Flagmeier, Patrick, Horrocks, Mathew H., Kjaergaard, Magnus, Shammas, Sarah L., Jackson, Sophie E., Dobson, Christopher M., Klenerman, David
Publicado 2018

A mechanistic model of tau amyloid aggregation based on direct observation of oligomers

por Shammas, Sarah L., Garcia, Gonzalo A., Kumar, Satish, Kjaergaard, Magnus, Horrocks, Mathew H., Shivji, Nadia, Mandelkow, Eva, Knowles, Tuomas P.J., Mandelkow, Eckhard, Klenerman, David
Publicado 2015

Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors

por Milles, Sigrid, Mercadante, Davide, Aramburu, Iker Valle, Jensen, Malene Ringkjøbing, Banterle, Niccolò, Koehler, Christine, Tyagi, Swati, Clarke, Jane, Shammas, Sarah L., Blackledge, Martin, Gräter, Frauke, Lemke, Edward A.
Publicado 2015