Role of Hsp70 in Post-Translational Protein Targeting: Tail-Anchored Membrane Proteins and Beyond

por Shan, Shu-ou
Publicado 2023

Fidelity of Cotranslational Protein Targeting to the Endoplasmic Reticulum

por Hsieh, Hao-Hsuan, Shan, Shu-ou
Publicado 2021

Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation

por Shan, Shu-ou, Chandrasekar, Sowmya, Walter, Peter
Publicado 2007

Regulation of cargo recognition, commitment, and unloading drives cotranslational protein targeting

por Saraogi, Ishu, Akopian, David, Shan, Shu-ou
Publicado 2014

Ribosome profiling reveals multiple roles of SecA in cotranslational protein export

por Zhu, Zikun, Wang, Shuai, Shan, Shu-ou
Publicado 2022

Mechanism of Association and Reciprocal Activation of Two GTPases

por Shan, Shu-ou, Stroud, Robert M, Walter, Peter
Publicado 2004

SecA mediates cotranslational targeting and translocation of an inner membrane protein

por Wang, Shuai, Yang, Chien-I, Shan, Shu-ou
Publicado 2017

J-domain proteins promote client relay from Hsp70 during tail-anchored membrane protein targeting

por Cho, Hyunju, Shim, Woo Jun, Liu, Yumeng, Shan, Shu-ou
Publicado 2021

Detection of Sequential Polyubiquitylation on a Millisecond Time-Scale

por Pierce, Nathan W., Kleiger, Gary, Shan, Shu-ou, Deshaies, Raymond J.
Publicado 2009

Activated GTPase movement on an RNA scaffold drives cotranslational protein targeting

por Shen, Kuang, Arslan, Sinan, Akopian, David, Ha, Taekjip, Shan, Shu-ou
Publicado 2012

SecYEG activates GTPases to drive the completion of cotranslational protein targeting

por Akopian, David, Dalal, Kush, Shen, Kuang, Duong, Franck, Shan, Shu-ou
Publicado 2013

A ribosome-associated chaperone enables substrate triage in a cotranslational protein targeting complex

por Hsieh, Hao-Hsuan, Lee, Jae Ho, Chandrasekar, Sowmya, Shan, Shu-ou
Publicado 2020

Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting

por Lam, Vinh Q., Akopian, David, Rome, Michael, Henningsen, Doug, Shan, Shu-ou
Publicado 2010

A molecular recognition feature mediates ribosome-induced SRP-receptor assembly during protein targeting

por Hwang Fu, Yu-Hsien, Chandrasekar, Sowmya, Lee, Jae Ho, Shan, Shu-ou
Publicado 2019

Multiple selection filters ensure accurate tail-anchored membrane protein targeting

por Rao, Meera, Okreglak, Voytek, Chio, Un Seng, Cho, Hyunju, Walter, Peter, Shan, Shu-ou
Publicado 2016

Molecular mechanism of cotranslational membrane protein recognition and targeting by SecA

por Wang, Shuai, Jomaa, Ahmad, Jaskolowski, Mateusz, Yang, Chien-I, Ban, Nenad, Shan, Shu-ou
Publicado 2019

Structure of the quaternary complex between SRP, SR, and translocon bound to the translating ribosome

por Jomaa, Ahmad, Fu, Yu-Hsien Hwang, Boehringer, Daniel, Leibundgut, Marc, Shan, Shu-ou, Ban, Nenad
Publicado 2017

Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle

por Jomaa, Ahmad, Eitzinger, Simon, Zhu, Zikun, Chandrasekar, Sowmya, Kobayashi, Kan, Shan, Shu-ou, Ban, Nenad
Publicado 2021

System-wide analyses reveal essential roles of N-terminal protein modification in bacterial membrane integrity

por Yang, Chien-I, Zhu, Zikun, Jones, Jeffrey J., Lomenick, Brett, Chou, Tsui-Fen, Shan, Shu-ou
Publicado 2022

Dodecamer assembly of a metazoan AAA(+) chaperone couples substrate extraction to refolding

por Gupta, Arpit, Lentzsch, Alfred M., Siegel, Alex, Yu, Zanlin, Chio, Un Seng, Cheng, Yifan, Shan, Shu-ou
Publicado 2023