Modelling the Response of FOXO Transcription Factors to Multiple Post-Translational Modifications Made by Ageing-Related Signalling Pathways

por Smith, Graham R., Shanley, Daryl P.
Publicado 2010

Computational modelling of the regulation of Insulin signalling by oxidative stress

por Smith, Graham R, Shanley, Daryl P
Publicado 2013

Cytosolic Self-DNA—A Potential Source of Chronic Inflammation in Aging

por Akbari, Mansour, Shanley, Daryl P., Bohr, Vilhelm A., Rasmussen, Lene Juel
Publicado 2021

Modeling and gene knockdown to assess the contribution of nonsense-mediated decay, premature termination, and selenocysteine insertion to the selenoprotein hierarchy

por Zupanic, Anze, Meplan, Catherine, Huguenin, Grazielle V.B., Hesketh, John E., Shanley, Daryl P.
Publicado 2016

‘Molecular habituation’ as a potential mechanism of gradual homeostatic loss with age

por Martinez Guimera, Alvaro, Welsh, Ciaran M., Proctor, Carole J., McArdle, Anne, Shanley, Daryl P.
Publicado 2018

Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21- Mediated Early Senescence Signalling

por Dolan, David W. P., Zupanic, Anze, Nelson, Glyn, Hall, Philip, Miwa, Satomi, Kirkwood, Thomas B. L., Shanley, Daryl P.
Publicado 2015

Detecting translational regulation by change point analysis of ribosome profiling data sets

por Zupanic, Anze, Meplan, Catherine, Grellscheid, Sushma N., Mathers, John C., Kirkwood, Tom B.L., Hesketh, John E., Shanley, Daryl P.
Publicado 2014

Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

por Dalle Pezze, Piero, Nelson, Glyn, Otten, Elsje G., Korolchuk, Viktor I., Kirkwood, Thomas B. L., von Zglinicki, Thomas, Shanley, Daryl P.
Publicado 2014

Systems modelling ageing: from single senescent cells to simple multi-cellular models

por Martinez Guimera, Alvaro, Welsh, Ciaran, Dalle Pezze, Piero, Fullard, Nicola, Nelson, Glyn, Roger, Mathilde F., Przyborski, Stefan A., Shanley, Daryl P.
Publicado 2017

Genome‐Wide MicroRNA and Gene Analysis of Mesenchymal Stem Cell Chondrogenesis Identifies an Essential Role and Multiple Targets for miR‐140‐5p

por Barter, Matt J., Tselepi, Maria, Gómez, Rodolfo, Woods, Steven, Hui, Wang, Smith, Graham R., Shanley, Daryl P., Clark, Ian M., Young, David A.
Publicado 2015

PyCoTools: a Python toolbox for COPASI

por Welsh, Ciaran M, Fullard, Nicola, Proctor, Carole J, Martinez-Guimera, Alvaro, Isfort, Robert J, Bascom, Charles C, Tasseff, Ryan, Przyborski, Stefan A, Shanley, Daryl P
Publicado 2018

Predominant Asymmetrical Stem Cell Fate Outcome Limits the Rate of Niche Succession in Human Colonic Crypts

por Stamp, Craig, Zupanic, Anze, Sachdeva, Ashwin, Stoll, Elizabeth A., Shanley, Daryl P., Mathers, John C., Kirkwood, Thomas B.L., Heer, Rakesh, Simons, Benjamin D., Turnbull, Doug M., Greaves, Laura C.
Publicado 2018

A systems study reveals concurrent activation of AMPK and mTOR by amino acids

por Pezze, Piero Dalle, Ruf, Stefanie, Sonntag, Annika G., Langelaar-Makkinje, Miriam, Hall, Philip, Heberle, Alexander M., Navas, Patricia Razquin, van Eunen, Karen, Tölle, Regine C., Schwarz, Jennifer J., Wiese, Heike, Warscheid, Bettina, Deitersen, Jana, Stork, Björn, Fäßler, Erik, Schäuble, Sascha, Hahn, Udo, Horvatovich, Peter, Shanley, Daryl P., Thedieck, Kathrin
Publicado 2016