Dynamic mechanism of GPCR-mediated β-arrestin: a potential therapeutic agent discovery of biased drug

por Xu, Zheng, Shao, Zhenhua
Publicado 2022

A Periodic Event-Triggered Design of Robust [Image: see text] Filtering for T-S Fuzzy Discrete-Time Systems

por Zhang, Zuchang, Lin, Dongliang, Wang, Xingyi, Shao, Zhenhua, Lin, Wenzhong
Publicado 2019

Ligand recognition and biased agonism of the D1 dopamine receptor

por Teng, Xiao, Chen, Sijia, Nie, Yingying, Xiao, Peng, Yu, Xiao, Shao, Zhenhua, Zheng, Sanduo
Publicado 2022

Allosteric modulation of G protein-coupled receptor signaling

por Shen, Siyuan, Zhao, Chang, Wu, Chao, Sun, Suyue, Li, Ziyan, Yan, Wei, Shao, Zhenhua
Publicado 2023

High-resolution crystal structure of the human CB1 cannabinoid receptor

por Shao, Zhenhua, Yin, Jie, Chapman, Karen, Grzemska, Magdalena, Clark, Lindsay, Wang, Junmei, Rosenbaum, Daniel M.
Publicado 2016

Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region

por Gong, Deshun, Yang, Fan, Li, Fudong, Qian, Dandan, Wu, Minhao, Shao, Zhenhua, Wu, Mian, Wu, Jihui, Shi, Yunyu
Publicado 2013

Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2

por Cheng, Lin, Sun, Suyue, Wang, Heli, Zhao, Chang, Tian, Xiaowen, Liu, Ying, Fu, Ping, Shao, Zhenhua, Chai, Renjie, Yan, Wei
Publicado 2023

Fluid dynamics alter Caenorhabditis elegans body length via TGF-β/DBL-1 neuromuscular signaling

por Harada, Shunsuke, Hashizume, Toko, Nemoto, Kanako, Shao, Zhenhua, Higashitani, Nahoko, Etheridge, Timothy, Szewczyk, Nathaniel J, Fukui, Keiji, Higashibata, Akira, Higashitani, Atsushi
Publicado 2016

Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode

por Yan, Wei, Cheng, Lin, Wang, Wei, Wu, Chao, Yang, Xin, Du, Xiaozhe, Ma, Liang, Qi, Shiqian, Wei, Yuquan, Lu, Zhiliang, Yang, Shengyong, Shao, Zhenhua
Publicado 2020

Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition

por Yuan, Yuan, Jia, Guowen, Wu, Chao, Wang, Wei, Cheng, Lin, Li, Qian, Li, Ziyan, Luo, Kaidong, Yang, Shengyong, Yan, Wei, Su, Zhaoming, Shao, Zhenhua
Publicado 2021

Structure, function and drug discovery of GPCR signaling

por Cheng, Lin, Xia, Fan, Li, Ziyan, Shen, Chenglong, Yang, Zhiqian, Hou, Hanlin, Sun, Suyue, Feng, Yuying, Yong, Xihao, Tian, Xiaowen, Qin, Hongxi, Yan, Wei, Shao, Zhenhua
Publicado 2023

Mechanism of activation and biased signaling in complement receptor C5aR1

por Feng, Yuying, Zhao, Chang, Deng, Yue, Wang, Heli, Ma, Liang, Liu, Sicen, Tian, Xiaowen, Wang, Bo, Bin, Yan, Chen, Peipei, Yan, Wei, Fu, Ping, Shao, Zhenhua
Publicado 2023

Crystal structure of tRNA m(1)G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate

por Shao, Zhenhua, Yan, Wei, Peng, Junhui, Zuo, Xiaobing, Zou, Yang, Li, Fudong, Gong, Deshun, Ma, Rongsheng, Wu, Jihui, Shi, Yunyu, Zhang, Zhiyong, Teng, Maikun, Li, Xu, Gong, Qingguo
Publicado 2014

Molecular mechanism of agonism and inverse agonism in ghrelin receptor

por Qin, Jiao, Cai, Ye, Xu, Zheng, Ming, Qianqian, Ji, Su-Yu, Wu, Chao, Zhang, Huibing, Mao, Chunyou, Shen, Dan-Dan, Hirata, Kunio, Ma, Yanbin, Yan, Wei, Zhang, Yan, Shao, Zhenhua
Publicado 2022

Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine

por Zhao, Jie, Fu, Hong, Yu, Jingjing, Hong, Weiqi, Tian, Xiaowen, Qi, Jieyu, Sun, Suyue, Zhao, Chang, Wu, Chao, Xu, Zheng, Cheng, Lin, Chai, Renjie, Yan, Wei, Wei, Xiawei, Shao, Zhenhua
Publicado 2023

Non-classical ferroptosis inhibition by a small molecule targeting PHB2

por Yang, Wei, Mu, Bo, You, Jing, Tian, Chenyu, Bin, Huachao, Xu, Zhiqiang, Zhang, Liting, Ma, Ronggang, Wu, Ming, Zhang, Guo, Huang, Chong, Li, Linli, Shao, Zhenhua, Dai, Lunzhi, Désaubry, Laurent, Yang, Shengyong
Publicado 2022