Dentine Lead Levels in Asymptomatic Philadelphia School Children: Subclinical Exposure in High and Low Risk Groups

por Needleman, Herbert L., Shapiro, Irving M.
Publicado 1974

Transcriptional profiling of the nucleus pulposus: say yes to notochord

por Shapiro, Irving M, Risbud, Makarand V
Publicado 2010

Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP

por Johnson, Zariel I., Shapiro, Irving M., Risbud, Makarand V.
Publicado 2014

Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration

por Gorth, Deborah J., Shapiro, Irving M., Risbud, Makarand V.
Publicado 2018

Regulated Production of Mineralization-competent Matrix Vesicles in Hypertrophic Chondrocytes

por Kirsch, Thorsten, Nah, Hyun-Duck, Shapiro, Irving M., Pacifici, Maurizio
Publicado 1997

Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death

por Silagi, Elizabeth S., Batista, Philip, Shapiro, Irving M., Risbud, Makarand V.
Publicado 2018

Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation

por Choi, Hyowon, Madhu, Vedavathi, Shapiro, Irving M., Risbud, Makarand V.
Publicado 2019

BMP-2 and TGF-β Stimulate Expression of β1,3-Glucuronosyl Transferase 1 (GlcAT-1) in Nucleus Pulposus Cells Through AP1, TonEBP, and Sp1: Role of MAPKs

por Hiyama, Akihiko, Gogate, Shilpa S, Gajghate, Sachin, Mochida, Joji, Shapiro, Irving M, Risbud, Makarand V
Publicado 2010

Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus

por Liu, Chao, Choi, Hyowon, Johnson, Zariel I., Tian, Jiwei, Shapiro, Irving M., Risbud, Makarand V.
Publicado 2017

GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc

por Johnston, Shira N., Silagi, Elizabeth S., Madhu, Vedavathi, Nguyen, Duc H., Shapiro, Irving M., Risbud, Makarand V.
Publicado 2023

Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health

por Suyama, Kaori, Silagi, Elizabeth S., Choi, Hyowon, Sakabe, Kou, Mochida, Joji, Shapiro, Irving M., Risbud, Makarand V.
Publicado 2016

Abcc6 Null Mice—a Model for Mineralization Disorder PXE Shows Vertebral Osteopenia Without Enhanced Intervertebral Disc Calcification With Aging

por Boneski, Paige K., Madhu, Vedavathi, Tomlinson, Ryan E., Shapiro, Irving M., van de Wetering, Koen, Risbud, Makarand V.
Publicado 2022

Matrix Gla Protein Is a Developmental Regulator of Chondrocyte Mineralization And, When Constitutively Expressed, Blocks Endochondral and Intramembranous Ossification in the Limb

por Yagami, Kimitoshi, Suh, Jo-Young, Enomoto-Iwamoto, Motomi, Koyama, Eiki, Abrams, William R., Shapiro, Irving M., Pacifici, Maurizio, Iwamoto, Masahiro
Publicado 1999

Loss of HIF-1α in the Notochord Results in Cell Death and Complete Disappearance of the Nucleus Pulposus

por Merceron, Christophe, Mangiavini, Laura, Robling, Alexander, Wilson, Tremika LeShan, Giaccia, Amato J., Shapiro, Irving M., Schipani, Ernestina, Risbud, Makarand V.
Publicado 2014

Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections

por Gilbertie, Jessica M., Schnabel, Lauren V., Hickok, Noreen J., Jacob, Megan E., Conlon, Brian P., Shapiro, Irving M., Parvizi, Javad, Schaer, Thomas P.
Publicado 2019

Tendinosis develops from age‐ and oxygen tension‐dependent modulation of Rac1 activity

por McBeath, Rowena, Edwards, Richard W., O’Hara, Brian J., Maltenfort, Mitchell G., Parks, Susan M., Steplewski, Andrzej, Osterman, A. Lee, Shapiro, Irving M.
Publicado 2019

An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes

por Markova, Dessislava Z, Kepler, Christopher K, Addya, Sankar, Murray, Hallie B, Vaccaro, Alexander R, Shapiro, Irving M, Greg Anderson, D, Albert, Todd J, Risbud, Makarand V
Publicado 2013

An organ culture system to model early degenerative changes of the intervertebral disc

por Ponnappan, Ravi K, Markova, Dessislava Z, Antonio, Paul JD, Murray, Hallie B, Vaccaro, Alexander R, Shapiro, Irving M, Anderson, D Greg, Albert, Todd J, Risbud, Makarand V
Publicado 2011

Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice

por Novais, Emanuel J., Tran, Victoria A., Johnston, Shira N., Darris, Kayla R., Roupas, Alex J., Sessions, Garrett A., Shapiro, Irving M., Diekman, Brian O., Risbud, Makarand V.
Publicado 2021