Epigenetic control of an oncogenic microRNA, miR-155, by BRCA1

por Chang, Suhwan, Sharan, Shyam K.
Publicado 2012

RAD52 S346X variant reduces breast cancer risk in BRCA2 mutation carriers

por Biswas, Kajal, Sharan, Shyam K.
Publicado 2020

Translating Embryogenesis to Generate Organoids: Novel Approaches to Personalized Medicine

por Sahu, Sounak, Sharan, Shyam K.
Publicado 2020

Exploring role of 5hmC as potential marker of chemoresistance

por Kharat, Suhas S., Sharan, Shyam K.
Publicado 2020

Resolving RAD51C function in late stages of homologous recombination

por Sharan, Shyam K, Kuznetsov, Sergey G
Publicado 2007

Genetically engineered mouse models for hereditary cancer syndromes

por Biswas, Kajal, Mohammed, Altaf, Sharan, Shyam K., Shoemaker, Robert H.
Publicado 2023

Protocol for the saturation and multiplexing of genetic variants using CRISPR-Cas9

por Sahu, Sounak, Sullivan, Teresa, Southon, Eileen, Caylor, Dylan, Geh, Josephine, Sharan, Shyam K.
Publicado 2023

A handcuff model for the cohesin complex

por Zhang, Nenggang, Kuznetsov, Sergey G., Sharan, Shyam K., Li, Kaiyi, Rao, Pulivarthi H., Pati, Debananda
Publicado 2008

Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity

por Palmer, Nathan, Talib, S. Zakiah A., Goh, Christine M. F., Biswas, Kajal, Sharan, Shyam K., Kaldis, Philipp
Publicado 2023

Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay

por Sirisena, Nirmala, Biswas, Kajal, Sullivan, Teresa, Stauffer, Stacey, Cleveland, Linda, Southon, Eileen, Dissanayake, Vajira H. W., Sharan, Shyam K.
Publicado 2020

MMTV-Espl1 Transgenic Mice Develop Aneuploid, Estrogen Receptor Alpha (ERα)-Positive Mammary Adenocarcinomas

por Mukherjee, Malini, Ge, Gouqing, Zhang, Nenggang, Edwards, David G., Sumazin, Pavel, Sharan, Shyam K., Rao, Pulivarthi H., Medina, Daniel, Pati, Debananda
Publicado 2013

Growth factor dependency in mammary organoids regulates ductal morphogenesis during organ regeneration

por Sahu, Sounak, Albaugh, Mary E., Martin, Betty K., Patel, Nimit L., Riffle, Lisa, Mackem, Susan, Kalen, Joseph D., Sharan, Shyam K.
Publicado 2022

A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays

por Biswas, Kajal, Lipton, Gary B., Stauffer, Stacey, Sullivan, Teresa, Cleveland, Linda, Southon, Eileen, Reid, Susan, Magidson, Valentin, Iversen, Edwin S., Sharan, Shyam K.
Publicado 2020

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

por Hartford, Suzanne A., Chittela, Rajanikant, Ding, Xia, Vyas, Aradhana, Martin, Betty, Burkett, Sandra, Haines, Diana C., Southon, Eileen, Tessarollo, Lino, Sharan, Shyam K.
Publicado 2016

Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect

por Singh, Smriti, Narayanan, Sathiya Pandi, Biswas, Kajal, Gupta, Amit, Ahuja, Neha, Yadav, Sandhya, Panday, Rajendra Kumar, Samaiya, Atul, Sharan, Shyam K., Shukla, Sanjeev
Publicado 2017

BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage

por Biswas, Kajal, Philip, Subha, Yadav, Aditya, Martin, Betty K., Burkett, Sandra, Singh, Vaibhav, Babbar, Anav, North, Susan Lynn, Chang, Suhwan, Sharan, Shyam K.
Publicado 2018

PKM2 dictates the poised chromatin state of PFKFB3 promoter to enhance breast cancer progression

por Pandkar, Madhura R, Raveendran, Adarsh, Biswas, Kajal, Mutnuru, Srinivas Abhishek, Mishra, Jharna, Samaiya, Atul, Malys, Tyler, Mitrophanov, Alexander Y, Sharan, Shyam K, Shukla, Sanjeev
Publicado 2023

Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration

por Kim, Sinae, Song, Jin Hoi, Kim, Seokho, Qu, Peng, Martin, Betty K., Sehareen, Waheed S., Haines, Diana C., Lin, Pengnian C., Sharan, Shyam K., Chang, Suhwan
Publicado 2016

The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation

por Xu, Xiaoping, Ni, Kai, He, Yafeng, Ren, Jianke, Sun, Chongkui, Liu, Yie, Aladjem, Mirit I., Burkett, Sandra, Finney, Richard, Ding, Xia, Sharan, Shyam K., Muegge, Kathrin
Publicado 2021

Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15

por Moro, Ramona N., Biswas, Uddipta, Kharat, Suhas S., Duzanic, Filip D., Das, Prosun, Stavrou, Maria, Raso, Maria C., Freire, Raimundo, Chaudhuri, Arnab Ray, Sharan, Shyam K., Penengo, Lorenza
Publicado 2023