High content screening miniaturization and single cell imaging of mature human feeder layer-free iPSC-derived neurons

por Sharlow, Elizabeth R., Llaneza, Danielle C., Grever, William E., Mingledorff, Garnett A., Mendelson, Anna J., Bloom, George S., Lazo, John S.
Publicado 2023

Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility

por LaValle, Courtney R, Bravo-Altamirano, Karla, Giridhar, Karthik V, Chen, Jun, Sharlow, Elizabeth, Lazo, John S, Wipf, Peter, Wang, Q Jane
Publicado 2010

Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity

por Sharlow, Elizabeth R., Mustata Wilson, Gabriela, Close, David, Leimgruber, Stephanie, Tandon, Manuj, Reed, Robyn B., Shun, Tong Ying, Wang, Q. Jane, Wipf, Peter, Lazo, John S.
Publicado 2011

Identification of Potent Chemotypes Targeting Leishmania major Using a High-Throughput, Low-Stringency, Computationally Enhanced, Small Molecule Screen

por Sharlow, Elizabeth R., Close, David, Shun, Tongying, Leimgruber, Stephanie, Reed, Robyn, Mustata, Gabriela, Wipf, Peter, Johnson, Jacob, O'Neil, Michael, Grögl, Max, Magill, Alan J., Lazo, John S.
Publicado 2009

A Target-Based High Throughput Screen Yields Trypanosoma brucei Hexokinase Small Molecule Inhibitors with Antiparasitic Activity

por Sharlow, Elizabeth R., Lyda, Todd A., Dodson, Heidi C., Mustata, Gabriela, Morris, Meredith T., Leimgruber, Stephanie S., Lee, Kuo-Hsiung, Kashiwada, Yoshiki, Close, David, Lazo, John S., Morris, James C.
Publicado 2010

Design, Synthesis, and Biological Evaluation of PKD Inhibitors

por George, Kara M., Frantz, Marie-Céline, Bravo-Altamirano, Karla, LaValle, Courtney R., Tandon, Manuj, Leimgruber, Stephanie, Sharlow, Elizabeth R., Lazo, John S., Wang, Q. Jane, Wipf, Peter
Publicado 2011

Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer

por Lazo, John S., Sharlow, Elizabeth R., Cornelison, Robert, Hart, Duncan J., Llaneza, Danielle C., Mendelson, Anna J., Rastelli, Ettore J., Tasker, Nikhil R., Landen, Charles N., Wipf, Peter
Publicado 2021

Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor

por McQueeney, Kelley E., Salamoun, Joseph M., Burnett, James C., Barabutis, Nektarios, Pekic, Paula, Lewandowski, Sophie L., Llaneza, Danielle C., Cornelison, Robert, Bai, Yunpeng, Zhang, Zhong-Yin, Catravas, John D., Landen, Charles N., Wipf, Peter, Lazo, John S., Sharlow, Elizabeth R.
Publicado 2017

Chemical genetics of Plasmodium falciparum

por Guiguemde, W. Armand, Shelat, Anang A., Bouck, David, Duffy, Sandra, Crowther, Gregory J., Davis, Paul H., Smithson, David C., Connelly, Michele, Clark, Julie, Zhu, Fangyi, Jiménez-Díaz, María B, Martinez, María S, Wilson, Emily B., Tripathi, Abhai K., Gut, Jiri, Sharlow, Elizabeth R., Bathurst, Ian, El Mazouni, Farah, Fowble, Joseph W, Forquer, Isaac, McGinley, Paula L, Castro, Steve, Angulo-Barturen, Iñigo, Ferrer, Santiago, Rosenthal, Philip J., DeRisi, Joseph L, Sullivan, David J., Lazo, John S., Roos, David S., Riscoe, Michael K., Phillips, Margaret A., Rathod, Pradipsinh K., Van Voorhis, Wesley C., Avery, Vicky M, Guy, R. Kiplin
Publicado 2010