Lespedeza davurica (Lax.) Schindl. Extract Protects against Cytokine-Induced β-Cell Damage and Streptozotocin-Induced Diabetes

por Sharma, Bhesh Raj, Rhyu, Dong Young
Publicado 2015

Distinct role of IL-1β in instigating disease in Sharpin(cpdm) mice

por Gurung, Prajwal, Sharma, Bhesh Raj, Kanneganti, Thirumala-Devi
Publicado 2016

Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolism in C57BL/KsJ-db/db mice via PI3K/AKT signaling pathway in myocytes

por Sharma, Bhesh Raj, Kim, Hyun Jung, Rhyu, Dong Young
Publicado 2015

Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis)

por Sharma, Bhesh Raj, Karki, Rajendra, Rajesh, Yetirajam, Kanneganti, Thirumala-Devi
Publicado 2023

Anti-nociceptive and anti-inflammatory effects of the methanolic extract of Opuntia humifusa stem

por Sharma, Bhesh Raj, Park, Chul Min, Choi, Jong Won, Rhyu, Dong Young
Publicado 2017

The Transcription Factor IRF9 Promotes Colorectal Cancer via Modulating the IL-6/STAT3 Signaling Axis

por Sharma, Bhesh Raj, Karki, Rajendra, Sundaram, Balamurugan, Wang, Yaqiu, Vogel, Peter, Kanneganti, Thirumala-Devi
Publicado 2022

ZBP1 Drives IAV-Induced NLRP3 Inflammasome Activation and Lytic Cell Death, PANoptosis, Independent of the Necroptosis Executioner MLKL

por Malireddi, R. K. Subbarao, Sharma, Bhesh Raj, Bynigeri, Ratnakar R., Wang, Yaqiu, Lu, Jianlin, Kanneganti, Thirumala-Devi
Publicado 2023

Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology

por Mall, Raghvendra, Bynigeri, Ratnakar R, Karki, Rajendra, Malireddi, R K Subbarao, Sharma, Bhesh Raj, Kanneganti, Thirumala-Devi
Publicado 2022

ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis)

por Banoth, Balaji, Tuladhar, Shraddha, Karki, Rajendra, Sharma, Bhesh Raj, Briard, Benoit, Kesavardhana, Sannula, Burton, Amanda, Kanneganti, Thirumala-Devi
Publicado 2021

Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression

por Malireddi, R.K. Subbarao, Bynigeri, Ratnakar R., Kancharana, Balabhaskararao, Sharma, Bhesh Raj, Burton, Amanda R., Pelletier, Stephane, Kanneganti, Thirumala-Devi
Publicado 2022

DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response

por Kesavardhana, Sannula, Samir, Parimal, Zheng, Min, Malireddi, R.K. Subbarao, Karki, Rajendra, Sharma, Bhesh Raj, Place, David E., Briard, Benoit, Vogel, Peter, Kanneganti, Thirumala-Devi
Publicado 2021

Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation

por Wang, Yaqiu, Karki, Rajendra, Mall, Raghvendra, Sharma, Bhesh Raj, Kalathur, Ravi C., Lee, SangJoon, Kancharana, Balabhaskararao, So, Matthew, Combs, Katie L., Kanneganti, Thirumala-Devi
Publicado 2022

NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer

por Karki, Rajendra, Man, Si Ming, Malireddi, R.K. Subbarao, Kesavardhana, Sannula, Zhu, Qifan, Burton, Amanda R., Sharma, Bhesh Raj, Qi, Xiaopeng, Pelletier, Stephane, Vogel, Peter, Rosenstiel, Philip, Kanneganti, Thirumala-Devi
Publicado 2016

Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

por Christgen, Shelbi, Zheng, Min, Kesavardhana, Sannula, Karki, Rajendra, Malireddi, R. K. Subbarao, Banoth, Balaji, Place, David E., Briard, Benoit, Sharma, Bhesh Raj, Tuladhar, Shraddha, Samir, Parimal, Burton, Amanda, Kanneganti, Thirumala-Devi
Publicado 2020

Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes

por Karki, Rajendra, Sharma, Bhesh Raj, Tuladhar, Shraddha, Williams, Evan Peter, Zalduondo, Lillian, Samir, Parimal, Zheng, Min, Sundaram, Balamurugan, Banoth, Balaji, Malireddi, R. K. Subbarao, Schreiner, Patrick, Neale, Geoffrey, Vogel, Peter, Webby, Richard, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi
Publicado 2020

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

por Karki, Rajendra, Sharma, Bhesh Raj, Tuladhar, Shraddha, Williams, Evan Peter, Zalduondo, Lillian, Samir, Parimal, Zheng, Min, Sundaram, Balamurugan, Banoth, Balaji, Malireddi, R.K. Subbarao, Schreiner, Patrick, Neale, Geoffrey, Vogel, Peter, Webby, Richard, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi
Publicado 2021

ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection

por Karki, Rajendra, Lee, SangJoon, Mall, Raghvendra, Pandian, Nagakannan, Wang, Yaqiu, Sharma, Bhesh Raj, Malireddi, RK Subbarao, Yang, Dong, Trifkovic, Sanja, Steele, Jacob A., Connelly, Jon P., Vishwanath, Gella, Sasikala, Mitnala, Reddy, Duvvur Nageshwar, Vogel, Peter, Pruett-Miller, Shondra M., Webby, Richard, Jonsson, Colleen Beth, Kanneganti, Thirumala-Devi
Publicado 2022