Challenges and Limitations of Targeting the Keap1-Nrf2 Pathway for Neurotherapeutics: Bach1 De-Repression to the Rescue

por Hushpulian, Dmitry M., Ammal Kaidery, Navneet, Ahuja, Manuj, Poloznikov, Andrey A., Sharma, Sudarshana M., Gazaryan, Irina G., Thomas, Bobby
Publicado 2021

Nanofiber-expanded human CD34(+) cells heal cutaneous wounds in streptozotocin-induced diabetic mice

por Kanji, Suman, Das, Manjusri, Joseph, Matthew, Aggarwal, Reeva, Sharma, Sudarshana M., Ostrowski, Michael, Pompili, Vincent J., Mao, Hai-Quan, Das, Hiranmoy
Publicado 2019

Harnessing the Therapeutic Potential of the Nrf2/Bach1 Signaling Pathway in Parkinson’s Disease

por Ahuja, Manuj, Kaidery, Navneet Ammal, Dutta, Debashis, Attucks, Otis C., Kazakov, Eliot H., Gazaryan, Irina, Matsumoto, Mitsuyo, Igarashi, Kazuhiko, Sharma, Sudarshana M., Thomas, Bobby
Publicado 2022

TNF Inhibits Notch-1 in Skeletal Muscle Cells by Ezh2 and DNA Methylation Mediated Repression: Implications in Duchenne Muscular Dystrophy

por Acharyya, Swarnali, Sharma, Sudarshana M., Cheng, Alfred S., Ladner, Katherine J., He, Wei, Kline, William, Wang, Huating, Ostrowski, Michael C., Huang, Tim H., Guttridge, Denis C.
Publicado 2010

Eomes partners with PU.1 and MITF to Regulate Transcription Factors Critical for osteoclast differentiation

por Carey, Heather A., Hildreth, Blake E., Samuvel, Devadoss J., Thies, Katie A., Rosol, Thomas J., Toribio, Ramiro E., Charles, Julia F., Ostrowski, Michael C., Sharma, Sudarshana M.
Publicado 2018

Bach1 derepression is neuroprotective in a mouse model of Parkinson’s disease

por Ahuja, Manuj, Ammal Kaidery, Navneet, Attucks, Otis C., McDade, Erin, Hushpulian, Dmitry M., Gaisin, Arsen, Gaisina, Irina, Ahn, Young Hoon, Nikulin, Sergey, Poloznikov, Andrey, Gazaryan, Irina, Yamamoto, Masayuki, Matsumoto, Mitsuyo, Igarashi, Kazuhiko, Sharma, Sudarshana M., Thomas, Bobby
Publicado 2021

Ets2 in Tumor Fibroblasts Promotes Angiogenesis in Breast Cancer

por Wallace, Julie A., Li, Fu, Balakrishnan, Subhasree, Cantemir-Stone, Carmen Z., Pecot, Thierry, Martin, Chelsea, Kladney, Raleigh D., Sharma, Sudarshana M., Trimboli, Anthony J., Fernandez, Soledad A., Yu, Lianbo, Rosol, Thomas J., Stromberg, Paul C., Lesurf, Robert, Hallett, Michael, Park, Morag, Leone, Gustavo, Ostrowski, Michael C.
Publicado 2013

Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation

por Carey, Heather A., Hildreth, Blake E., Geisler, Jennifer A., Nickel, Mara C., Cabrera, Jennifer, Ghosh, Sankha, Jiang, Yue, Yan, Jing, Lee, James, Makam, Sandeep, Young, Nicholas A., Valiente, Giancarlo R., Jarjour, Wael N., Huang, Kun, Rosol, Thomas J., Toribio, Ramiro E., Charles, Julia F., Ostrowski, Michael C., Sharma, Sudarshana M.
Publicado 2018

NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model

por Peterson, Jennifer M., Wang, David J., Shettigar, Vikram, Roof, Steve R., Canan, Benjamin D., Bakkar, Nadine, Shintaku, Jonathan, Gu, Jin-Mo, Little, Sean C., Ratnam, Nivedita M., Londhe, Priya, Lu, Leina, Gaw, Christopher E., Petrosino, Jennifer M., Liyanarachchi, Sandya, Wang, Huating, Janssen, Paul M. L., Davis, Jonathan P., Ziolo, Mark T., Sharma, Sudarshana M., Guttridge, Denis C.
Publicado 2018

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia()

por Pitarresi, Jason R., Liu, Xin, Sharma, Sudarshana M., Cuitiño, Maria C., Kladney, Raleigh D., Mace, Thomas A., Donohue, Sydney, Nayak, Sunayana G., Qu, Chunjing, Lee, James, Woelke, Sarah A., Trela, Stefan, LaPak, Kyle, Yu, Lianbo, McElroy, Joseph, Rosol, Thomas J., Shakya, Reena, Ludwig, Thomas, Lesinski, Gregory B., Fernandez, Soledad A., Konieczny, Stephen F., Leone, Gustavo, Wu, Jinghai, Ostrowski, Michael C.
Publicado 2016

STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer

por Lefler, Julia E, MarElia-Bennett, Catherine B, Thies, Katie A, Hildreth, Blake E, Sharma, Sudarshana M, Pitarresi, Jason R, Han, Lu, Everett, Caroline, Koivisto, Christopher, Cuitino, Maria C, Timmers, Cynthia D, O’Quinn, Elizabeth, Parrish, Melodie, Romeo, Martin J, Linke, Amanda J, Hobbs, G Aaron, Leone, Gustavo, Guttridge, Denis C, Zimmers, Teresa A, Lesinski, Gregory B, Ostrowski, Michael C
Publicado 2022

Pten in Stromal Fibroblasts Suppresses Mammary Epithelial Tumors

por Trimboli, Anthony J., Cantemir-Stone, Carmen Z., Li, Fu, Wallace, Julie A., Merchant, Anand, Creasap, Nicholas, Thompson, John C., Caserta, Enrico, Wang, Hui, Chong, Jean-Leon, Naidu, Shan, Wei, Guo, Sharma, Sudarshana M., Stephens, Julie A., Fernandez, Soledad A., Gurcan, Metin N., Weinstein, Michael B., Barsky, Sanford H., Yee, Lisa, Rosol, Thomas J., Stromberg, Paul C., Robinson, Michael L., Pepin, Francois, Hallett, Michael, Park, Morag, Ostrowski, Michael C., Leone, Gustavo
Publicado 2009