Steps in commutative algebra

por Sharp, Rodney Y, Bruce, J W
Publicado 2001

Local cohomology: an algebraic introduction with geometric applications

por Brodmann, M P, Sharp, R Y
Publicado 2012

Lack of a role for MRP1 in platinum drug resistance in human ovarian cancer cell lines.

por Sharp, S. Y., Smith, V., Hobbs, S., Kelland, L. R.
Publicado 1998

Effects of a new antioestrogen, idoxifene, on cisplatin- and doxorubicin-sensitive and -resistant human ovarian carcinoma cell lines.

por Sharp, S. Y., Rowlands, M. G., Jarman, M., Kelland, L. R.
Publicado 1994

Parametric analysis of an efficient boundary condition to control outlet flow rates in large arterial networks

por Lo, Sharp C. Y., McCullough, Jon W. S., Coveney, Peter V.
Publicado 2022

In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473.

por Holford, J., Sharp, S. Y., Murrer, B. A., Abrams, M., Kelland, L. R.
Publicado 1998

BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma

por Beale, P J, Rogers, P, Boxall, F, Sharp, S Y, Kelland, L R
Publicado 2000

Co-Crystalization and In Vitro Biological Characterization of 5-Aryl-4-(5-Substituted-2-4-Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors

por Sharp, Swee Y., Roe, S. Mark, Kazlauskas, Egidijus, Čikotienė, Inga, Workman, Paul, Matulis, Daumantas, Prodromou, Chrisostomos
Publicado 2012

Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition

por Beloueche-Babari, Mounia, Arunan, Vaitha, Jackson, L. Elizabeth, Perusinghe, Nina, Sharp, Swee Y., Workman, Paul, Leach, Martin O.
Publicado 2010

Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches

por Darby, John F., Vidler, Lewis R., Simpson, Peter J., Al-Lazikani, Bissan, Matthews, Stephen J., Sharp, Swee Y., Pearl, Laurence H., Hoelder, Swen, Workman, Paul
Publicado 2020

Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectrosco...

por Rodrigues, Loreta M, Chung, Yuen-Li, Al Saffar, Nada M S, Sharp, Swee Y, Jackson, Laura E, Banerji, Udai, Stubbs, Marion, Leach, Martin O, Griffiths, John R, Workman, Paul
Publicado 2012

Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766)

por Chessum, Nicola E. A., Sharp, Swee Y., Caldwell, John J., Pasqua, A. Elisa, Wilding, Birgit, Colombano, Giampiero, Collins, Ian, Ozer, Bugra, Richards, Meirion, Rowlands, Martin, Stubbs, Mark, Burke, Rosemary, McAndrew, P. Craig, Clarke, Paul A., Workman, Paul, Cheeseman, Matthew D., Jones, Keith
Publicado 2017

HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies

por Pasqua, A. Elisa, Sharp, Swee Y., Chessum, Nicola E. A., Hayes, Angela, Pellegrino, Loredana, Tucker, Michael J., Miah, Asadh, Wilding, Birgit, Evans, Lindsay E., Rye, Carl S., Mok, N. Yi, Liu, Manjuan, Henley, Alan T., Gowan, Sharon, De Billy, Emmanuel, te Poele, Robert, Powers, Marissa, Eccles, Suzanne A., Clarke, Paul A., Raynaud, Florence I., Workman, Paul, Jones, Keith, Cheeseman, Matthew D.
Publicado 2023

Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9

por Rye, Carl S., Chessum, Nicola E. A., Lamont, Scott, Pike, Kurt G., Faulder, Paul, Demeritt, Julie, Kemmitt, Paul, Tucker, Julie, Zani, Lorenzo, Cheeseman, Matthew D., Isaac, Rosie, Goodwin, Louise, Boros, Joanna, Raynaud, Florence, Hayes, Angela, Henley, Alan T., de Billy, Emmanuel, Lynch, Christopher J., Sharp, Swee Y., te Poele, Robert, Fee, Lisa O’, Foote, Kevin M., Green, Stephen, Workman, Paul, Jones, Keith
Publicado 2016

Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen

por Cheeseman, Matthew D., Chessum, Nicola E. A., Rye, Carl S., Pasqua, A. Elisa, Tucker, Michael J., Wilding, Birgit, Evans, Lindsay E., Lepri, Susan, Richards, Meirion, Sharp, Swee Y., Ali, Salyha, Rowlands, Martin, O’Fee, Lisa, Miah, Asadh, Hayes, Angela, Henley, Alan T., Powers, Marissa, te Poele, Robert, De Billy, Emmanuel, Pellegrino, Loredana, Raynaud, Florence, Burke, Rosemary, van Montfort, Rob L. M., Eccles, Suzanne A., Workman, Paul, Jones, Keith
Publicado 2016