SUMOylation Is Required for Optimal TRAF3 Signaling Capacity

por Miliara, Sophia, Gkouskou, Kalliopi K., Sharp, Tyson V., Eliopoulos, Aristides G.
Publicado 2013

Suppression of AGO2 by miR-132 as a determinant of miRNA-mediated silencing in human primary endothelial cells

por Leonov, German, Shah, Kunal, Yee, Daniel, Timmis, Jon, Sharp, Tyson V., Lagos, Dimitris
Publicado 2015

Expression of polycomb protein BMI‐1 maintains the plasticity of basal bronchial epithelial cells

por Torr, Elizabeth, Heath, Meg, Mee, Maureen, Shaw, Dominick, Sharp, Tyson V., Sayers, Ian
Publicado 2016

MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells

por Yee, Daniel, Shah, Kunal M., Coles, Mark C., Sharp, Tyson V., Lagos, Dimitris
Publicado 2017

PU.1 is a major transcriptional activator of the tumour suppressor gene LIMD1

por Foxler, Daniel E., James, Victoria, Shelton, Samuel J., Vallim, Thomas Q. de A., Shaw, Peter E., Sharp, Tyson V.
Publicado 2011

SMG-1 and mTORC1 Act Antagonistically to Regulate Response to Injury and Growth in Planarians

por González-Estévez, Cristina, Felix, Daniel A., Smith, Matthew D., Paps, Jordi, Morley, Simon J., James, Victoria, Sharp, Tyson V., Aboobaker, A. Aziz
Publicado 2012

Extended lifespan of bronchial epithelial cells maintains normal cellular phenotype and transcriptome integrity

por O'Loughlin, Jonathan, Hall, Robert J., Bhaker, Sangita, Portelli, Michael A., Henry, Amanda, Pang, Vincent, Bates, David O., Sharp, Tyson V., Sayers, Ian
Publicado 2021

Oxidative stress downstream of mTORC1 but not AKT causes a proliferative defect in cancer cells resistant to PI3K inhibition

por Dermit, M, Casado, P, Rajeeve, V, Wilkes, E H, Foxler, D E, Campbell, H, Critchlow, S, Sharp, T V, Gribben, J G, Unwin, R, Cutillas, P R
Publicado 2017

Ajmaline blocks I(Na) and I(Kr) without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters

por Miller, Duncan C., Harmer, Stephen C., Poliandri, Ariel, Nobles, Muriel, Edwards, Elizabeth C., Ware, James S., Sharp, Tyson V., McKay, Tristan R., Dunkel, Leo, Lambiase, Pier D., Tinker, Andrew
Publicado 2017

LIMD1 is induced by and required for LMP1 signaling, and protects EBV-transformed cells from DNA damage-induced cell death

por Wang, Ling, Howell, Mary E.A., McPeak, Brooke, Riggs, Katrina, Kohne, Carissa, Yohanon, Jether Uel, Foxler, Daniel E., Sharp, Tyson V., Moorman, Jonathan P., Yao, Zhi Q., Ning, Shunbin
Publicado 2017

S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells

por Warner, Matthew J., Bridge, Katherine S., Hewitson, James P., Hodgkinson, Michael R., Heyam, Alex, Massa, Bailey C., Haslam, Jessica C., Chatzifrangkeskou, Maria, Evans, Gareth J.O., Plevin, Michael J., Sharp, Tyson V., Lagos, Dimitris
Publicado 2016

Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes

por Davidson, Kathryn, Grevitt, Paul, Contreras-Gerenas, Maria F., Bridge, Katherine S., Hermida, Miguel, Shah, Kunal M., Mardakheh, Faraz K., Stubbs, Mark, Burke, Rosemary, Casado, Pedro, Cutillas, Pedro R., Martin, Sarah A., Sharp, Tyson V.
Publicado 2021

Oncometabolite induced primary cilia loss in pheochromocytoma

por O’Toole, Samuel M, Watson, David S, Novoselova, Tatiana V, Romano, Lisa E L, King, Peter J, Bradshaw, Teisha Y, Thompson, Clare L, Knight, Martin M, Sharp, Tyson V, Barnes, Michael R, Srirangalingam, Umasuthan, Drake, William M, Chapple, J Paul
Publicado 2018

Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins

por Bridge, Katherine S., Shah, Kunal M., Li, Yigen, Foxler, Daniel E., Wong, Sybil C.K., Miller, Duncan C., Davidson, Kathryn M., Foster, John G., Rose, Ruth, Hodgkinson, Michael R., Ribeiro, Paulo S., Aboobaker, A. Aziz, Yashiro, Kenta, Wang, Xiaozhong, Graves, Paul R., Plevin, Michael J., Lagos, Dimitris, Sharp, Tyson V.
Publicado 2017

A HIF–LIMD1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia

por Foxler, Daniel E, Bridge, Katherine S, Foster, John G, Grevitt, Paul, Curry, Sean, Shah, Kunal M, Davidson, Kathryn M, Nagano, Ai, Gadaleta, Emanuela, Rhys, Hefin I, Kennedy, Paul T, Hermida, Miguel A, Chang, Ting‐Yu, Shaw, Peter E, Reynolds, Louise E, McKay, Tristan R, Wang, Hsei‐Wei, Ribeiro, Paulo S, Plevin, Michael J, Lagos, Dimitris, Lemoine, Nicholas R, Rajan, Prabhakar, Graham, Trevor A, Chelala, Claude, Hodivala‐Dilke, Kairbaan M, Spendlove, Ian, Sharp, Tyson V
Publicado 2018