The effects of age and systemic metabolism on anti-tumor T cell responses

por Drijvers, Jefte M, Sharpe, Arlene H, Haigis, Marcia C
Publicado 2020

B7-1 or B7-2 Is Required to Produce the Lymphoproliferative Phenotype in Mice Lacking Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4)

por Mandelbrot, Didier A., McAdam, Alexander J., Sharpe, Arlene H.
Publicado 1999

Microbiota-dependent regulation of costimulatory and coinhibitory pathways via innate immune sensors and implications for immunotherapy

por Park, Joon Seok, Gazzaniga, Francesca S., Kasper, Dennis L., Sharpe, Arlene H.
Publicado 2023

Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade

por Freeman, Gordon J., Wherry, E. John, Ahmed, Rafi, Sharpe, Arlene H.
Publicado 2006

Understanding adverse events of immunotherapy: A mechanistic perspective

por Burke, Kelly P., Grebinoski, Stephanie, Sharpe, Arlene H., Vignali, Dario A.A.
Publicado 2020

Gata6(+) resident peritoneal macrophages promote the growth of liver metastasis

por Hossain, Mokarram, Shim, Raymond, Lee, Woo-Yong, Sharpe, Arlene H., Kubes, Paul
Publicado 2022

Studies in B7-Deficient Mice Reveal a Critical Role for B7 Costimulation in Both Induction and Effector Phases of Experimental Autoimmune Encephalomyelitis

por Chang, Tammy T., Jabs, Claudia, Sobel, Raymond A., Kuchroo, Vijay K., Sharpe, Arlene H.
Publicado 1999

JEM women in STEM: Unique journeys with a common purpose

por O’Garra, Anne, Belkaid, Yasmine, Sharpe, Arlene, Kaech, Susan, Cherry, Sara, Passegué, Emmanuelle
Publicado 2020

Essential and Partially Overlapping Role of CD3γ and CD3δ for Development of αβ and γδ T Lymphocytes

por Wang, Baoping, Wang, Ninghai, Salio, Mariolina, Sharpe, Arlene, Allen, Deborah, She, Jian, Terhorst, Cox
Publicado 1998

Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8(+) T cells

por Odorizzi, Pamela M., Pauken, Kristen E., Paley, Michael A., Sharpe, Arlene, Wherry, E. John
Publicado 2015

CD28 Costimulation Regulates Genome-Wide Effects on Alternative Splicing

por Butte, Manish J., Lee, Sun Jung, Jesneck, Jonathan, Keir, Mary E., Haining, W. Nicholas, Sharpe, Arlene H.
Publicado 2012

Core skin DC signatures control immune tolerance to skin cancer and limit anti-tumor immunity

por Nirschl, Christopher, Liu, Yong, Sarin, Kavita, Suarez-Farinas, Mayte, Chau, David, Sage, Peter, Sharpe, Arlene, Anandasabapathy, Niroshana
Publicado 2015

PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells

por Good-Jacobson, Kim L., Szumilas, Courtney G., Chen, Lieping, Sharpe, Arlene H., Tomayko, Mary M., Shlomchik, Mark J.
Publicado 2010

Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors

por Wang, Ninghai, Halibozek, Peter J., Yigit, Burcu, Zhao, Hui, O’Keeffe, Michael S., Sage, Peter, Sharpe, Arlene, Terhorst, Cox
Publicado 2015

FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program

por Hou, Shenda, Clement, Rachel L., Diallo, Alos, Blazar, Bruce R., Rudensky, Alexander Y., Sharpe, Arlene H., Sage, Peter T.
Publicado 2019

The aging lung: Physiology, disease, and immunity

por Schneider, Jaime L., Rowe, Jared H., Garcia-de-Alba, Carolina, Kim, Carla F., Sharpe, Arlene H., Haigis, Marcia C.
Publicado 2021

PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability

por Hurrell, Benjamin P., Helou, Doumet Georges, Howard, Emily, Painter, Jacob D., Shafiei-Jahani, Pedram, Sharpe, Arlene H., Akbari, Omid
Publicado 2022

Helicobacter pylori cag Pathogenicity Island's Role in B7-H1 Induction and Immune Evasion

por Lina, Taslima T., Alzahrani, Shatha, House, Jennifer, Yamaoka, Yoshio, Sharpe, Arlene H., Rampy, Bill A., Pinchuk, Irina V., Reyes, Victor E.
Publicado 2015

CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease

por Sakai, Shunsuke, Kauffman, Keith D., Sallin, Michelle A., Sharpe, Arlene H., Young, Howard A., Ganusov, Vitaly V., Barber, Daniel L.
Publicado 2016

Podoplanin(+) tumor lymphatics are rate limiting for breast cancer metastasis

por Chen, Yang, Keskin, Doruk, Sugimoto, Hikaru, Kanasaki, Keizo, Phillips, Patricia E., Bizarro, Lauren, Sharpe, Arlene, LeBleu, Valerie S., Kalluri, Raghu
Publicado 2018