The effects of age and systemic metabolism on anti-tumor T cell responses

por Drijvers, Jefte M, Sharpe, Arlene H, Haigis, Marcia C
Publicado 2020

B7-1 or B7-2 Is Required to Produce the Lymphoproliferative Phenotype in Mice Lacking Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4)

por Mandelbrot, Didier A., McAdam, Alexander J., Sharpe, Arlene H.
Publicado 1999

Microbiota-dependent regulation of costimulatory and coinhibitory pathways via innate immune sensors and implications for immunotherapy

por Park, Joon Seok, Gazzaniga, Francesca S., Kasper, Dennis L., Sharpe, Arlene H.
Publicado 2023

Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade

por Freeman, Gordon J., Wherry, E. John, Ahmed, Rafi, Sharpe, Arlene H.
Publicado 2006

Understanding adverse events of immunotherapy: A mechanistic perspective

por Burke, Kelly P., Grebinoski, Stephanie, Sharpe, Arlene H., Vignali, Dario A.A.
Publicado 2020

Gata6(+) resident peritoneal macrophages promote the growth of liver metastasis

por Hossain, Mokarram, Shim, Raymond, Lee, Woo-Yong, Sharpe, Arlene H., Kubes, Paul
Publicado 2022

Studies in B7-Deficient Mice Reveal a Critical Role for B7 Costimulation in Both Induction and Effector Phases of Experimental Autoimmune Encephalomyelitis

por Chang, Tammy T., Jabs, Claudia, Sobel, Raymond A., Kuchroo, Vijay K., Sharpe, Arlene H.
Publicado 1999

CD28 Costimulation Regulates Genome-Wide Effects on Alternative Splicing

por Butte, Manish J., Lee, Sun Jung, Jesneck, Jonathan, Keir, Mary E., Haining, W. Nicholas, Sharpe, Arlene H.
Publicado 2012

PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells

por Good-Jacobson, Kim L., Szumilas, Courtney G., Chen, Lieping, Sharpe, Arlene H., Tomayko, Mary M., Shlomchik, Mark J.
Publicado 2010

FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program

por Hou, Shenda, Clement, Rachel L., Diallo, Alos, Blazar, Bruce R., Rudensky, Alexander Y., Sharpe, Arlene H., Sage, Peter T.
Publicado 2019

The aging lung: Physiology, disease, and immunity

por Schneider, Jaime L., Rowe, Jared H., Garcia-de-Alba, Carolina, Kim, Carla F., Sharpe, Arlene H., Haigis, Marcia C.
Publicado 2021

PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability

por Hurrell, Benjamin P., Helou, Doumet Georges, Howard, Emily, Painter, Jacob D., Shafiei-Jahani, Pedram, Sharpe, Arlene H., Akbari, Omid
Publicado 2022

Helicobacter pylori cag Pathogenicity Island's Role in B7-H1 Induction and Immune Evasion

por Lina, Taslima T., Alzahrani, Shatha, House, Jennifer, Yamaoka, Yoshio, Sharpe, Arlene H., Rampy, Bill A., Pinchuk, Irina V., Reyes, Victor E.
Publicado 2015

CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease

por Sakai, Shunsuke, Kauffman, Keith D., Sallin, Michelle A., Sharpe, Arlene H., Young, Howard A., Ganusov, Vitaly V., Barber, Daniel L.
Publicado 2016

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

por Francisco, Loise M., Salinas, Victor H., Brown, Keturah E., Vanguri, Vijay K., Freeman, Gordon J., Kuchroo, Vijay K., Sharpe, Arlene H.
Publicado 2009

Inactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma Irradiation

por Boytz, RuthMabel, Seitz, Scott, Gaudiano, Emily, Patten, J. J., Keiser, Patrick T., Connor, John H., Sharpe, Arlene H., Davey, Robert A.
Publicado 2022

Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection

por Ha, Sang-Jun, Mueller, Scott N., Wherry, E. John, Barber, Daniel L., Aubert, Rachael D., Sharpe, Arlene H., Freeman, Gordon J., Ahmed, Rafi
Publicado 2008

Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses

por Clement, Rachel L., Daccache, Joe, Mohammed, Mostafa T., Diallo, Alos, Blazar, Bruce R., Kuchroo, Vijay K., Lovitch, Scott B., Sharpe, Arlene H., Sage, Peter T.
Publicado 2019

The Cell Surface Receptor SLAM Controls T Cell and Macrophage Functions

por Wang, Ninghai, Satoskar, Abhay, Faubion, William, Howie, Duncan, Okamoto, Susumu, Feske, Stefan, Gullo, Charles, Clarke, Kareem, Sosa, Miriam Rodriguez, Sharpe, Arlene H., Terhorst, Cox
Publicado 2004

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

por Juneja, Vikram R., McGuire, Kathleen A., Manguso, Robert T., LaFleur, Martin W., Collins, Natalie, Haining, W. Nicholas, Freeman, Gordon J., Sharpe, Arlene H.
Publicado 2017