A combined fine needle aspiration and spectral flow cytometry approach to assess human germinal center responses to SARS-CoV-2 vaccination

por Bettini, Emily, Lederer, Katlyn, Sharpe, Hannah, Kaminski, Mary, Jones, Lisa, Locci, Michela
Publicado 2022

The early landscape of coronavirus disease 2019 vaccine development in the UK and rest of the world

por Sharpe, Hannah R., Gilbride, Ciaran, Allen, Elizabeth, Belij‐Rammerstorfer, Sandra, Bissett, Cameron, Ewer, Katie, Lambe, Teresa
Publicado 2020

The Integration of Human and Veterinary Studies for Better Understanding and Management of Crimean-Congo Haemorrhagic Fever

por Gilbride, Ciaran, Saunders, Jack, Sharpe, Hannah, Maze, Emmanuel Atangana, Limon, Georgina, Ludi, Anna Barbara, Lambe, Teresa, Belij-Rammerstorfer, Sandra
Publicado 2021

A Multi-Filovirus Vaccine Candidate: Co-Expression of Ebola, Sudan, and Marburg Antigens in a Single Vector

por Sebastian, Sarah, Flaxman, Amy, Cha, Kuan M., Ulaszewska, Marta, Gilbride, Ciaran, Sharpe, Hannah, Wright, Edward, Spencer, Alexandra J., Dowall, Stuart, Hewson, Roger, Gilbert, Sarah, Lambe, Teresa
Publicado 2020

Use of an Outbred Rat Hepacivirus Challenge Model for Design and Evaluation of Efficacy of Different Immunization Strategies for Hepatitis C Virus

por Atcheson, Erwan, Li, Wenqin, Bliss, Carly M., Chinnakannan, Senthil, Heim, Kathrin, Sharpe, Hannah, Hutchings, Claire, Dietrich, Isabelle, Nguyen, Dung, Kapoor, Amit, Jarvis, Michael A., Klenerman, Paul, Barnes, Eleanor, Simmonds, Peter
Publicado 2019

Reduced Ebola vaccine responses in CMV(+) young adults is associated with expansion of CD57(+)KLRG1(+) T cells

por Bowyer, Georgina, Sharpe, Hannah, Venkatraman, Navin, Ndiaye, Pierre Birahim, Wade, Djibril, Brenner, Nicole, Mentzer, Alex, Mair, Catherine, Waterboer, Tim, Lambe, Teresa, Dieye, Tandakha, Mboup, Souleymane, Hill, Adrian V.S., Ewer, Katie J.
Publicado 2020

CMV-associated T cell and NK cell terminal differentiation does not affect immunogenicity of ChAdOx1 vaccination

por Sharpe, Hannah R., Provine, Nicholas M., Bowyer, Georgina S., Moreira Folegatti, Pedro, Belij-Rammerstorfer, Sandra, Flaxman, Amy, Makinson, Rebecca, Hill, Adrian V.S., Ewer, Katie J., Pollard, Andrew J., Klenerman, Paul, Gilbert, Sarah, Lambe, Teresa
Publicado 2022

Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice

por Spencer, Alexandra J., McKay, Paul F., Belij-Rammerstorfer, Sandra, Ulaszewska, Marta, Bissett, Cameron D., Hu, Kai, Samnuan, Karnyart, Blakney, Anna K., Wright, Daniel, Sharpe, Hannah R., Gilbride, Ciaran, Truby, Adam, Allen, Elizabeth R., Gilbert, Sarah C., Shattock, Robin J., Lambe, Teresa
Publicado 2021

IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies

por Friedrich, Matthias, Pohin, Mathilde, Jackson, Matthew A., Korsunsky, Ilya, Bullers, Samuel J., Rue-Albrecht, Kevin, Christoforidou, Zoe, Sathananthan, Dharshan, Thomas, Tom, Ravindran, Rahul, Tandon, Ruchi, Peres, Raphael Sanches, Sharpe, Hannah, Wei, Kevin, Watts, Gerald F. M., Mann, Elizabeth H., Geremia, Alessandra, Attar, Moustafa, McCuaig, Sarah, Thomas, Lloyd, Collantes, Elena, Uhlig, Holm H., Sansom, Stephen N., Easton, Alistair, Raychaudhuri, Soumya, Travis, Simon P., Powrie, Fiona M.
Publicado 2021

ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques

por van Doremalen, Neeltje, Lambe, Teresa, Spencer, Alexandra, Belij-Rammerstorfer, Sandra, Purushotham, Jyothi N., Port, Julia R., Avanzato, Victoria, Bushmaker, Trenton, Flaxman, Amy, Ulaszewska, Marta, Feldmann, Friederike, Allen, Elizabeth R., Sharpe, Hannah, Schulz, Jonathan, Holbrook, Myndi, Okumura, Atsushi, Meade-White, Kimberly, Pérez-Pérez, Lizzette, Bissett, Cameron, Gilbride, Ciaran, Williamson, Brandi N., Rosenke, Rebecca, Long, Dan, Ishwarbhai, Alka, Kailath, Reshma, Rose, Louisa, Morris, Susan, Powers, Claire, Lovaglio, Jamie, Hanley, Patrick W., Scott, Dana, Saturday, Greg, de Wit, Emmie, Gilbert, Sarah C., Munster, Vincent J.
Publicado 2020

Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

por Youngs, Jonathan, Provine, Nicholas M., Lim, Nicholas, Sharpe, Hannah R., Amini, Ali, Chen, Yi-Ling, Luo, Jian, Edmans, Matthew D., Zacharopoulou, Panagiota, Chen, Wentao, Sampson, Oliver, Paton, Robert, Hurt, William J., Duncan, David A., McNaughton, Anna L., Miao, Vincent N., Leaver, Susannah, Wyncoll, Duncan L. A., Ball, Jonathan, Hopkins, Philip, Skelly, Donal T., Barnes, Eleanor, Dunachie, Susanna, Ogg, Graham, Lambe, Teresa, Pavord, Ian, Shalek, Alex K., Thompson, Craig P., Xue, Luzheng, Macallan, Derek C., Goulder, Philip, Klenerman, Paul, Bicanic, Tihana
Publicado 2021

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

por van Doremalen, Neeltje, Lambe, Teresa, Spencer, Alexandra, Belij-Rammerstorfer, Sandra, Purushotham, Jyothi N., Port, Julia R., Avanzato, Victoria A., Bushmaker, Trenton, Flaxman, Amy, Ulaszewska, Marta, Feldmann, Friederike, Allen, Elizabeth R., Sharpe, Hannah, Schulz, Jonathan, Holbrook, Myndi, Okumura, Atsushi, Meade-White, Kimberly, Pérez-Pérez, Lizzette, Edwards, Nick J., Wright, Daniel, Bissett, Cameron, Gilbride, Ciaran, Williamson, Brandi N., Rosenke, Rebecca, Long, Dan, Ishwarbhai, Alka, Kailath, Reshma, Rose, Louisa, Morris, Susan, Powers, Claire, Lovaglio, Jamie, Hanley, Patrick W., Scott, Dana, Saturday, Greg, de Wit, Emmie, Gilbert, Sarah C., Munster, Vincent J.
Publicado 2020

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

por Graham, Simon P., McLean, Rebecca K., Spencer, Alexandra J., Belij-Rammerstorfer, Sandra, Wright, Daniel, Ulaszewska, Marta, Edwards, Jane C., Hayes, Jack W. P., Martini, Veronica, Thakur, Nazia, Conceicao, Carina, Dietrich, Isabelle, Shelton, Holly, Waters, Ryan, Ludi, Anna, Wilsden, Ginette, Browning, Clare, Bialy, Dagmara, Bhat, Sushant, Stevenson-Leggett, Phoebe, Hollinghurst, Philippa, Gilbride, Ciaran, Pulido, David, Moffat, Katy, Sharpe, Hannah, Allen, Elizabeth, Mioulet, Valerie, Chiu, Chris, Newman, Joseph, Asfor, Amin S., Burman, Alison, Crossley, Sylvia, Huo, Jiandong, Owens, Raymond J., Carroll, Miles, Hammond, John A., Tchilian, Elma, Bailey, Dalan, Charleston, Bryan, Gilbert, Sarah C., Tuthill, Tobias J., Lambe, Teresa
Publicado 2020

ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models

por Lambe, Teresa, Spencer, Alexandra J., Thomas, Kelly M., Gooch, Karen E., Thomas, Stephen, White, Andrew D., Humphries, Holly E., Wright, Daniel, Belij-Rammerstorfer, Sandra, Thakur, Nazia, Conceicao, Carina, Watson, Robert, Alden, Leonie, Allen, Lauren, Aram, Marilyn, Bewley, Kevin R., Brunt, Emily, Brown, Phillip, Cavell, Breeze E., Cobb, Rebecca, Fotheringham, Susan A., Gilbride, Ciaran, Harris, Debbie J., Ho, Catherine M. K., Hunter, Laura, Kennard, Chelsea L., Leung, Stephanie, Lucas, Vanessa, Ngabo, Didier, Ryan, Kathryn A., Sharpe, Hannah, Sarfas, Charlotte, Sibley, Laura, Slack, Gillian S., Ulaszewska, Marta, Wand, Nadina, Wiblin, Nathan R., Gleeson, Fergus V., Bailey, Dalan, Sharpe, Sally, Charlton, Sue, Salguero, Francisco J., Carroll, Miles W., Gilbert, Sarah C.
Publicado 2021