Tissue-specific CTCF/Cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo

por Hanssen, Lars L P, Kassouf, Mira T, Oudelaar, A Marieke, Biggs, Daniel, Preece, Chris, Downes, Damien J, Gosden, Matthew, Sharpe, Jacqueline A, Sloane-Stanley, Jacqueline A, Hughes, Jim R, Davies, Benjamin, Higgs, Douglas R
Publicado 2017

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia

por Mettananda, Sachith, Fisher, Chris A., Hay, Deborah, Badat, Mohsin, Quek, Lynn, Clark, Kevin, Hublitz, Philip, Downes, Damien, Kerry, Jon, Gosden, Matthew, Telenius, Jelena, Sloane-Stanley, Jackie A., Faustino, Paula, Coelho, Andreia, Doondeea, Jessica, Usukhbayar, Batchimeg, Sopp, Paul, Sharpe, Jacqueline A., Hughes, Jim R., Vyas, Paresh, Gibbons, Richard J., Higgs, Douglas R.
Publicado 2017

Reactivation of a developmentally silenced embryonic globin gene

por King, Andrew J., Songdej, Duantida, Downes, Damien J., Beagrie, Robert A., Liu, Siyu, Buckley, Megan, Hua, Peng, Suciu, Maria C., Marieke Oudelaar, A., Hanssen, Lars L. P., Jeziorska, Danuta, Roberts, Nigel, Carpenter, Stephanie J., Francis, Helena, Telenius, Jelena, Olijnik, Aude-Anais, Sharpe, Jacqueline A., Sloane-Stanley, Jacqueline, Eglinton, Jennifer, Kassouf, Mira T., Orkin, Stuart H., Pennacchio, Len A., Davies, James O. J., Hughes, Jim R., Higgs, Douglas R., Babbs, Christian
Publicado 2021