Dynamics of Macrophage, T and B Cell Infiltration Within Pulmonary Granulomas Induced by Mycobacterium tuberculosis in Two Non-Human Primate Models of Aerosol Infection

por Hunter, Laura, Hingley-Wilson, Suzie, Stewart, Graham R., Sharpe, Sally A., Salguero, Francisco Javier
Publicado 2022

Evidence for a Role for Interleukin-17, Th17 Cells and Iron Homeostasis in Protective Immunity against Tuberculosis in Cynomolgus Macaques

por Wareham, Alice S., Tree, Julia A., Marsh, Philip D., Butcher, Philip D., Dennis, Mike, Sharpe, Sally A.
Publicado 2014

ELISPOT Refinement Using Spot Morphology for Assessing Host Responses to Tuberculosis

por Sibley, Laura S., White, Andrew D., Marriott, Alice, Dennis, Michael J., Williams, Ann, Marsh, Philip D., Sharpe, Sally A.
Publicado 2012

Surveillance of Daughter Micronodule Formation Is a Key Factor for Vaccine Evaluation Using Experimental Infection Models of Tuberculosis in Macaques

por Nogueira, Isabel, Català, Martí, White, Andrew D., Sharpe, Sally A, Bechini, Jordi, Prats, Clara, Vilaplana, Cristina, Cardona, Pere-Joan
Publicado 2023

IV BCG Vaccination and Aerosol BCG Revaccination Induce Mycobacteria-Responsive γδ T Cells Associated with Protective Efficacy against M. tb Challenge

por Morrison, Alexandra L., Sarfas, Charlotte, Sibley, Laura, Williams, Jessica, Mabbutt, Adam, Dennis, Mike J., Lawrence, Steve, White, Andrew D., Bodman-Smith, Mark, Sharpe, Sally A.
Publicado 2023

Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles

por Bridge, Simon H, Sharpe, Sally A, Dennis, Mike J, Dowall, Stuart D, Getty, Brian, Anson, Donald S, Skinner, Michael A, Stewart, James P, Blanchard, Tom J
Publicado 2011

Characterization of the Infant Immune System and the Influence and Immunogenicity of BCG Vaccination in Infant and Adult Rhesus Macaques

por Sarfas, Charlotte, White, Andrew D., Sibley, Laura, Morrison, Alexandra L., Gullick, Jennie, Lawrence, Steve, Dennis, Mike J., Marsh, Philip D., Fletcher, Helen A., Sharpe, Sally A.
Publicado 2021

Protective Efficacy of Inhaled BCG Vaccination Against Ultra-Low Dose Aerosol M. tuberculosis Challenge in Rhesus Macaques

por White, Andrew D., Sarfas, Charlotte, Sibley, Laura S., Gullick, Jennie, Clark, Simon, Rayner, Emma, Gleeson, Fergus, Català, Martí, Nogueira, Isabel, Cardona, Pere-Joan, Vilaplana, Cristina, Dennis, Mike J., Williams, Ann, Sharpe, Sally A.
Publicado 2020

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human p...

por Tanner, Rachel, Hoogkamer, Emily, Bitencourt, Julia, White, Andrew, Boot, Charelle, Sombroek, Claudia C., Harris, Stephanie A., O'Shea, Matthew K., Wright, Daniel, Wittenberg, Rachel, Sarfas, Charlotte, Satti, Iman, Verreck, Frank A.W., Sharpe, Sally A., Fletcher, Helen A., McShane, Helen
Publicado 2021

A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates

por Tanner, Rachel, White, Andrew D., Boot, Charelle, Sombroek, Claudia C., O’Shea, Matthew K., Wright, Daniel, Hoogkamer, Emily, Bitencourt, Julia, Harris, Stephanie A., Sarfas, Charlotte, Wittenberg, Rachel, Satti, Iman, Fletcher, Helen A., Verreck, Frank A. W., Sharpe, Sally A., McShane, Helen
Publicado 2021

Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates

por White, Andrew D., Tran, Andy C., Sibley, Laura, Sarfas, Charlotte, Morrison, Alexandra L., Lawrence, Steve, Dennis, Mike, Clark, Simon, Zadi, Sirine, Lanni, Faye, Rayner, Emma, Copland, Alastair, Hart, Peter, Diogo, Gil Reynolds, Paul, Matthew J., Kim, Miyoung, Gleeson, Fergus, Salguero, Francisco J., Singh, Mahavir, Stehr, Matthias, Cutting, Simon M., Basile, Juan I., Rottenberg, Martin E., Williams, Ann, Sharpe, Sally A., Reljic, Rajko
Publicado 2023

One or two dose regimen of the SARS-CoV-2 synthetic DNA vaccine INO-4800 protects against respiratory tract disease burden in nonhuman primate challenge model

por Gooch, Karen E., Smith, Trevor R.F., Salguero, Francisco J., Fotheringham, Susan A., Watson, Robert J., Dennis, Mike J., Handley, Alastair, Humphries, Holly E., Longet, Stephanie, Tipton, Tom, Sarfas, Charlotte, Sibley, Laura, Slack, Gillian S., Rayner, Emma, Ryan, Kathryn A., Schultheis, Katherine, Ramos, Stephanie J., White, Andrew, Charlton, Sue, Sharpe, Sally A., Gleeson, Fergus, Humeau, Laurent M., Hall, Yper, Broderick, Kate E., Carroll, Miles W.
Publicado 2021