Imidazole Aldoximes Effective in Assisting Butyrylcholinesterase Catalysis of Organophosphate Detoxification

por Sit, Rakesh K., Fokin, Valery V., Amitai, Gabriel, Sharpless, K. Barry, Taylor, Palmer, Radić, Zoran
Publicado 2014

Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms

por Gahtory, Digvijay, Sen, Rickdeb, Pujari, Sidharam, Li, Suhua, Zheng, Qinheng, Moses, John E., Sharpless, K. Barry, Zuilhof, Han
Publicado 2018

Chain-Growth Sulfur(VI) Fluoride Exchange Polycondensation: Molecular Weight Control and Synthesis of Degradable Polysulfates

por Kim, Hyunseok, Zhao, Jiayu, Bae, Jinhye, Klivansky, Liana M., Dailing, Eric A., Liu, Yi, Cappiello, John R., Sharpless, K. Barry, Wu, Peng
Publicado 2021

Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification

por Hong, Senlian, Shi, Yujie, Wu, Nicholas C., Grande, Geramie, Douthit, Lacey, Wang, Hua, Zhou, Wen, Sharpless, K. Barry, Wilson, Ian A., Xie, Jia, Wu, Peng
Publicado 2019

Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis

por Lauwaet, Tineke, Miyamoto, Yukiko, Ihara, Sozaburo, Le, Christine, Kalisiak, Jarosław, Korthals, Keith A., Ghassemian, Majid, Smith, Diane K., Sharpless, K. Barry, Fokin, Valery V., Eckmann, Lars
Publicado 2020

Affinity selection of double-click triazole libraries for rapid discovery of allosteric modulators for GLP-1 receptor

por Xin, Ye, Liu, Shuo, Liu, Yan, Qian, Zhen, Liu, Hongyue, Zhang, Bingjie, Guo, Taijie, Thompson, Garth J., Stevens, Raymond C., Sharpless, K. Barry, Dong, Jiajia, Shui, Wenqing
Publicado 2023

Using Sulfuramidimidoyl Fluorides that Undergo Sulfur(VI) Fluoride Exchange for Inverse Drug Discovery

por Brighty, Gabriel J., Botham, Rachel C., Li, Suhua, Nelson, Luke, Mortenson, David E., Li, Gencheng, Morisseau, Christophe, Wang, Hua, Hammock, Bruce D., Sharpless, K. Barry, Kelly, Jeffery W.
Publicado 2020

Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors

por Cheng, Yunfei, Li, Gencheng, Smedley, Christopher J., Giel, Marie-Claire, Kitamura, Seiya, Woehl, Jordan L., Bianco, Giulia, Forli, Stefano, Homer, Joshua A., Cappiello, John R., Wolan, Dennis W., Moses, John E., Sharpless, K. Barry
Publicado 2022

Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia

por Garnar-Wortzel, Leopold, Bishop, Timothy R., Kitamura, Seiya, Milosevich, Natalia, Asiaban, Joshua N., Zhang, Xiaoyu, Zheng, Qinheng, Chen, Emily, Ramos, Anissa R., Ackerman, Christopher J., Hampton, Eric N., Chatterjee, Arnab K., Young, Travis S., Hull, Mitchell V., Sharpless, K. Barry, Cravatt, Benjamin F., Wolan, Dennis W., Erb, Michael A.
Publicado 2021