Reply: The role of DNAJB2 in amyotrophic lateral sclerosis

por Chen, Han-Jou, Shaw, Christopher E.
Publicado 2016

Disease Mechanisms and Therapeutic Approaches in C9orf72 ALS-FTD

por Mayl, Keith, Shaw, Christopher E., Lee, Youn-Bok
Publicado 2021

TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

por Scotter, Emma L., Chen, Han-Jou, Shaw, Christopher E.
Publicado 2015

Tar DNA-binding protein-43 (TDP-43) regulates axon growth in vitro and in vivo()

por Tripathi, Vineeta Bhasker, Baskaran, Pranetha, Shaw, Christopher E., Guthrie, Sarah
Publicado 2014

Generation of an Open-Access Patient-Derived iPSC Biobank for Amyotrophic Lateral Sclerosis Disease Modelling

por Hedges, Erin C., Cocks, Graham, Shaw, Christopher E., Nishimura, Agnes L.
Publicado 2023

Unpicking neurodegeneration in a dish with human pluripotent stem cells: One cell type at a time

por Bilican, Bilada, Serio, Andrea, Shaw, Christopher E, Maniatis, Tom, Chandran, Siddharthan
Publicado 2013

Generation of six induced pluripotent stem cell lines from patients with amyotrophic lateral sclerosis with associated genetic mutations in either FUS or ANXA11

por Hedges, Erin C., Topp, Simon, Shaw, Christopher E., Nishimura, Agnes L.
Publicado 2021

Heterogeneous Nuclear Ribonucleoprotein E2 (hnRNP E2) Is a Component of TDP-43 Aggregates Specifically in the A and C Pathological Subtypes of Frontotemporal Lobar Degeneration

por Kattuah, Wejdan, Rogelj, Boris, King, Andrew, Shaw, Christopher E., Hortobágyi, Tibor, Troakes, Claire
Publicado 2019

RNA Misprocessing in C9orf72-Linked Neurodegeneration

por Barker, Holly V., Niblock, Michael, Lee, Youn-Bok, Shaw, Christopher E., Gallo, Jean-Marc
Publicado 2017

Latent Cluster Analysis of ALS Phenotypes Identifies Prognostically Differing Groups

por Ganesalingam, Jeban, Stahl, Daniel, Wijesekera, Lokesh, Galtrey, Clare, Shaw, Christopher E., Leigh, P. Nigel, Al-Chalabi, Ammar
Publicado 2009

Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria

por Mórotz, Gábor M., De Vos, Kurt J., Vagnoni, Alessio, Ackerley, Steven, Shaw, Christopher E., Miller, Christopher C.J.
Publicado 2012

ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation

por King, Andrew, Troakes, Claire, Smith, Bradley, Nolan, Matthew, Curran, Olimpia, Vance, Caroline, Shaw, Christopher E., Al-Sarraj, Safa
Publicado 2015

Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their...

por Gomez-Deza, Jorge, Lee, Youn-bok, Troakes, Claire, Nolan, Matthew, Al-Sarraj, Safa, Gallo, Jean-Marc, Shaw, Christopher E.
Publicado 2015

Lack of association between TDP-43 pathology and tau mis-splicing in Alzheimer's disease

por Niblock, Michael, Hortobágyi, Tibor, Troakes, Claire, Al-Sarraj, Safa, Spickett, Carl, Jones, Rebecca, Shaw, Christopher E., Gallo, Jean-Marc
Publicado 2016

Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUS(WT) transgenic mice

por So, Eva, Mitchell, Jacqueline C, Memmi, Caroline, Chennell, George, Vizcay-Barrena, Gema, Allison, Leanne, Shaw, Christopher E, Vance, Caroline
Publicado 2018

A clinical tool for predicting survival in ALS

por Knibb, Jonathan A, Keren, Noa, Kulka, Anna, Leigh, P Nigel, Martin, Sarah, Shaw, Christopher E, Tsuda, Miho, Al-Chalabi, Ammar
Publicado 2016

ALS-linked FUS mutants affect the localization of U7 snRNP and replication-dependent histone gene expression in human cells

por Gadgil, Ankur, Walczak, Agnieszka, Stępień, Agata, Mechtersheimer, Jonas, Nishimura, Agnes Lumi, Shaw, Christopher E., Ruepp, Marc-David, Raczyńska, Katarzyna Dorota
Publicado 2021

Cytoplasmic TDP-43 is involved in cell fate during stress recovery

por Lee, Youn-Bok, Scotter, Emma L, Lee, Do-Young, Troakes, Claire, Mitchell, Jacqueline, Rogelj, Boris, Gallo, Jean-Marc, Shaw, Christopher E
Publicado 2021

Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments

por Ackerley, Steven, Thornhill, Paul, Grierson, Andrew J., Brownlees, Janet, Anderton, Brian H., Leigh, P. Nigel, Shaw, Christopher E., Miller, Christopher C.J.
Publicado 2003

Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons

por Ackerley, Steven, Grierson, Andrew J., Brownlees, Janet, Thornhill, Paul, Anderton, Brian H., Leigh, P. Nigel, Shaw, Christopher E., Miller, Christopher C.J.
Publicado 2000