Comprehensive assessment of computational algorithms in predicting cancer driver mutations

por Chen, Hu, Li, Jun, Wang, Yumeng, Ng, Patrick Kwok-Shing, Tsang, Yiu Huen, Shaw, Kenna R., Mills, Gordon B., Liang, Han
Publicado 2020

Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent®) a VEGFR2/PDGFRβ/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II t...

por Subbiah, Vivek, Meric-Bernstam, Funda, Mills, Gordon B, Shaw, Kenna R Mills, Bailey, Ann Marie, Rao, Priya, Ward, John F, Pagliaro, Lance C
Publicado 2014

Characteristics of percutaneous core biopsies adequate for next generation genomic sequencing

por Sabir, Sharjeel H., Krishnamurthy, Savitri, Gupta, Sanjay, Mills, Gordon B., Wei, Wei, Cortes, Andrea C., Mills Shaw, Kenna R., Luthra, Rajyalakshmi, Wallace, Michael J.
Publicado 2017

Use of a Targeted Exome Next-Generation Sequencing Panel Offers Therapeutic Opportunity and Clinical Benefit in a Subset of Patients With Advanced Cancers

por Kopetz, Scott, Mills Shaw, Kenna R., Lee, J. Jack, Zhang, Jiexin, Litzenburger, Beate, Holla, Vijaykumar, Kinyua, Walter, Broaddus, Emily, Daniels, Molly S., Meric-Bernstam, Funda, Broaddus, Russell R.
Publicado 2019

Genomic analysis of exceptional responder to regorafenib in treatment-refractory metastatic rectal cancer: a case report and review of the literature

por Korphaisarn, Krittiya, Loree, Jonathan M., Nguyen, Van, Coulson, Ryanne, Holla, Vijaykumar, Litzenburger, Beate C., Chen, Ken, Mills, Gordon B., Maru, Dipen M., Meric-Bernstan, Funda, Shaw, Kenna R. Mills, Kopetz, Scott
Publicado 2017

Integrated clinico-molecular profiling of appendiceal adenocarcinoma reveals a unique grade-driven entity distinct from colorectal cancer

por Raghav, Kanwal, Shen, John P., Jácome, Alexandre A., Guerra, Jennifer L., Scally, Christopher P., Taggart, Melissa W., Foo, Wai C., Matamoros, Aurelio, Shaw, Kenna R., Fournier, Keith, Overman, Michael J., Eng, Cathy
Publicado 2020

Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations

por Somaiah, Neeta, Beird, Hannah C, Barbo, Andrea, Song, Juhee, Mills Shaw, Kenna R., Wang, Wei-Lien, Eterovic, Karina, Chen, Ken, Lazar, Alexander, Conley, Anthony P., Ravi, Vinod, Hwu, Patrick, Futreal, Andrew, Simon, George, Meric-Bernstam, Funda, Hong, David
Publicado 2018

ALK: a tyrosine kinase target for cancer therapy

por Holla, Vijaykumar R., Elamin, Yasir Y., Bailey, Ann Marie, Johnson, Amber M., Litzenburger, Beate C., Khotskaya, Yekaterina B., Sanchez, Nora S., Zeng, Jia, Shufean, Md Abu, Shaw, Kenna R., Mendelsohn, John, Mills, Gordon B., Meric-Bernstam, Funda, Simon, George R.
Publicado 2017

American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange: From Inception to First Data Release and Beyond—Lessons Learned and Member Instit...

por Micheel, Christine M., Sweeney, Shawn M., LeNoue-Newton, Michele L., André, Fabrice, Bedard, Philippe L., Guinney, Justin, Meijer, Gerrit A., Rollins, Barrett J., Sawyers, Charles L., Schultz, Nikolaus, Shaw, Kenna R. Mills, Velculescu, Victor E., Levy, Mia A.
Publicado 2018

Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers

por Garmezy, Benjamin, Gheeya, Jinesh, Lin, Heather Y., Huang, Yuefan, Kim, Taebeom, Jiang, Xianli, Thein, Kyaw Z., Pilié, Patrick G., Zeineddine, Fadl, Wang, Wanlin, Shaw, Kenna R., Rodon, Jordi, Shen, John Paul, Yuan, Ying, Meric-Bernstam, Funda, Chen, Ken, Yap, Timothy A.
Publicado 2022

Actionability classification of variants of unknown significance correlates with functional effect

por Johnson, Amber, Ng, Patrick Kwok-Shing, Kahle, Michael, Castillo, Julia, Amador, Bianca, Wang, Yujia, Zeng, Jia, Holla, Vijaykumar, Vu, Thuy, Su, Fei, Kim, Sun-Hee, Conway, Tara, Jiang, Xianli, Chen, Ken, Shaw, Kenna R. Mills, Yap, Timothy A., Rodon, Jordi, Mills, Gordon B., Meric-Bernstam, Funda
Publicado 2023

A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory

por Arango, Natalia Paez, Brusco, Lauren, Shaw, Kenna R. Mills, Chen, Ken, Eterovic, Agda Karina, Holla, Vijaykumar, Johnson, Amber, Litzenburger, Beate, Khotskaya, Yekaterina B., Sanchez, Nora, Bailey, Ann, Zheng, Xiaofeng, Horombe, Chacha, Kopetz, Scott, Farhangfar, Carol J., Routbort, Mark, Broaddus, Russell, Bernstam, Elmer V., Mendelsohn, John, Mills, Gordon B., Meric-Bernstam, Funda
Publicado 2017

Correction: A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory

por Arango, Natalia Paez, Brusco, Lauren, Shaw, Kenna R. Mills, Chen, Ken, Eterovic, Agda Karina, Holla, Vijaykumar, Johnson, Amber, Litzenburger, Beate, Khotskaya, Yekaterina B., Sanchez, Nora, Bailey, Ann, Zheng, Xiaofeng, Horombe, Chacha, Kopetz, Scott, Farhangfar, Carol J., Routbort, Mark, Broaddus, Russell, Bernstam, Elmer V., Mendelsohn, John, Mills, Gordon B., Meric-Bernstam, Funda
Publicado 2019

RAC1 Alterations Induce Acquired Dabrafenib Resistance in Association with Anaplastic Transformation in a Papillary Thyroid Cancer Patient

por Bagheri-Yarmand, Rozita, Busaidy, Naifa L., McBeath, Elena, Danysh, Brian P., Evans, Kurt W., Moss, Tyler J., Akcakanat, Argun, Ng, Patrick K. S., Knippler, Christina M., Golden, Jalyn A., Williams, Michelle D., Multani, Asha S., Cabanillas, Maria E., Shaw, Kenna R., Meric-Bernstam, Funda, Shah, Manisha H., Ringel, Matthew D., Hofmann, Marie Claude
Publicado 2021

Clinical outcomes based on multigene profiling in metastatic breast cancer patients

por Basho, Reva K., de Melo Gagliato, Debora, Ueno, Naoto T., Wathoo, Chetna, Chen, Huiqin, Shariati, Maryam, Wei, Caimiao, Alvarez, Ricardo H., Moulder, Stacy L., Sahin, Aysegul A., Roy-Chowdhuri, Sinchita, Chavez-MacGregor, Mariana, Litton, Jennifer K., Valero, Vincent, Luthra, Raja, Zeng, Jia, Shaw, Kenna R., Mendelsohn, John, Mills, Gordon B., Tripathy, Debu, Meric-Bernstam, Funda
Publicado 2016

Association of Prediagnosis Obesity and Postdiagnosis Aspirin With Survival From Stage IV Colorectal Cancer

por Davis, Jennifer S., Chavez, Janelle C., Kok, Melissa, San Miguel, Yazmin, Lee, Hwa Young, Henderson, Henry, Overman, Michael J., Morris, Van, Kee, Bryan, Fogelman, David, Advani, Shailesh M., Johnson, Benny, Parseghian, Christine, Shen, John Paul, Dasari, Arvind, Shaw, Kenna R., Vilar, Eduardo, Raghav, Kanwal P., Shureiqi, Imad, Wolff, Robert A., Meric-Bernstam, Funda, Maru, Dipen, Menter, David G., Kopetz, Scott, Chang, Shine
Publicado 2022

Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set

por Roszik, Jason, Haydu, Lauren E., Hess, Kenneth R., Oba, Junna, Joon, Aron Y., Siroy, Alan E., Karpinets, Tatiana V., Stingo, Francesco C., Baladandayuthapani, Veera, Tetzlaff, Michael T., Wargo, Jennifer A., Chen, Ken, Forget, Marie-Andrée, Haymaker, Cara L., Chen, Jie Qing, Meric-Bernstam, Funda, Eterovic, Agda K., Shaw, Kenna R., Mills, Gordon B., Gershenwald, Jeffrey E., Radvanyi, Laszlo G., Hwu, Patrick, Futreal, P. Andrew, Gibbons, Don L., Lazar, Alexander J., Bernatchez, Chantale, Davies, Michael A., Woodman, Scott E.
Publicado 2016

A functional genomic approach to actionable gene fusions for precision oncology

por Li, Jun, Lu, Hengyu, Ng, Patrick Kwok-Shing, Pantazi, Angeliki, Ip, Carman Ka Man, Jeong, Kang Jin, Amador, Bianca, Tran, Richard, Tsang, Yiu Huen, Yang, Lixing, Song, Xingzhi, Dogruluk, Turgut, Ren, Xiaojia, Hadjipanayis, Angela, Bristow, Christopher A., Lee, Semin, Kucherlapati, Melanie, Parfenov, Michael, Tang, Jiabin, Seth, Sahil, Mahadeshwar, Harshad S., Mojumdar, Kamalika, Zeng, Dong, Zhang, Jianhua, Protopopov, Alexei, Seidman, Jonathan G., Creighton, Chad J., Lu, Yiling, Sahni, Nidhi, Shaw, Kenna R., Meric-Bernstam, Funda, Futreal, Andrew, Chin, Lynda, Scott, Kenneth L., Kucherlapati, Raju, Mills, Gordon B., Liang, Han
Publicado 2022

Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma

por Siroy, Alan E., Boland, Genevieve M., Milton, Denái R., Roszik, Jason, Frankian, Silva, Malke, Jared, Haydu, Lauren, Prieto, Victor G., Tetzlaff, Michael, Ivan, Doina, Wang, Wei-Lien, Torres-Cabala, Carlos, Curry, Jonathan, Roy-Chowdhuri, Sinchita, Broaddus, Russell, Rashid, Asif, Stewart, John, Gershenwald, Jeffrey E., Amaria, Rodabe N., Patel, Sapna P., Papadopoulos, Nicholas E., Bedikian, Agop, Hwu, Wen-Jen, Hwu, Patrick, Diab, Adi, Woodman, Scott E., Aldape, Kenneth D., Luthra, Rajyalakshmi, Patel, Keyur P., Shaw, Kenna R., Mills, Gordon B., Mendelsohn, John, Meric-Bernstam, Funda, Kim, Kevin B., Routbort, Mark J., Lazar, Alexander J., Davies, Michael A.
Publicado 2014