Quinoxaline 1,4-Dioxides: Advances in Chemistry and Chemotherapeutic Drug Development

por Buravchenko, Galina I., Shchekotikhin, Andrey E.
Publicado 2023

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property

por Cogoi, Susanna, Shchekotikhin, Andrey E., Xodo, Luigi E.
Publicado 2014

Synthesis of 7-amino-6-halogeno-3-phenylquinoxaline-2-carbonitrile 1,4-dioxides: a way forward for targeting hypoxia and drug resistance of cancer cells

por Buravchenko, Galina I., Scherbakov, Alexander M., Dezhenkova, Lyubov G., Monzote, Lianet, Shchekotikhin, Andrey E.
Publicado 2021

Computational and Biophysical Characterization of Heterocyclic Derivatives of Anthraquinone against Human Aurora Kinase A

por Singh, Mandeep, Haque, Md. Anzarul, Tikhomirov, Alexander S., Shchekotikhin, Andrey E., Das, Uddipan, Kaur, Punit
Publicado 2022

Subchronic Toxicity Study of Oral Anthrafuran on Rabbits

por Treshchalin, Michael I., Treshalina, Helen M., Golibrodo, Vasilisa A., Shchekotikhin, Andrey E., Pereverzeva, Eleonora R.
Publicado 2021

Experimental Evaluation of Anticancer Efficiency and Acute Toxicity of Anthrafuran for Oral Administration †

por Shchekotikhin, Andrey E., Treshalina, Helen M., Treshchalin, Michael I., Pereverzeva, Eleonora R., Isakova, Helen B., Tikhomirov, Alexander S.
Publicado 2020

Bacterial Cell Wall Analogue Peptides Control the Oligomeric States and Activity of the Glycopeptide Antibiotic Eremomycin: Solution NMR and Antimicrobial Studies

por Izsépi, László, Erdei, Réka, Tevyashova, Anna N., Grammatikova, Natalia E., Shchekotikhin, Andrey E., Herczegh, Pál, Batta, Gyula
Publicado 2021

Draft Genome Sequence of Streptomyces xinghaiensis (fradiae) OlgR, a Strain Resistant to Oligomycin A

por Bekker, Olga B., Vatlin, Aleksey A., Zakharevich, Natalia V., Lysenkova, Ludmila N., Shchekotikhin, Andrey E., Danilenko, Valery N.
Publicado 2019

Evaluation of Toxic Properties of New Glycopeptide Flavancin on Rats

por Treshchalin, Michael I., Polozkova, Vasilisa A., Moiseenko, Elena I., Treshalina, Helen M., Shchekotikhin, Andrey E., Pereverzeva, Eleonora R.
Publicado 2022

Essential Oil from Melaleuca leucadendra: Antimicrobial, Antikinetoplastid, Antiproliferative and Cytotoxic Assessment

por Monzote, Lianet, Scherbakov, Alexander M., Scull, Ramón, Satyal, Prabodh, Cos, Paul, Shchekotikhin, Andrey E., Gille, Lars, Setzer, William N.
Publicado 2020

Experimental Evaluation of the Hypersensitivity Reactions of a New Glycopeptide Antibiotic Flavancin in Animal Models

por Treshchalin, Michael I., Polozkova, Vasilisa A., Moiseenko, Elena I., Shchekotikhin, Andrey E., Dovzhenko, Svetlana A., Kobrin, Mikhail B., Pereverzeva, Eleonora R.
Publicado 2023

Engagement with tNOX (ENOX2) to Inhibit SIRT1 and Activate p53-Dependent and -Independent Apoptotic Pathways by Novel 4,11-Diaminoanthra[2,3-b]furan-5,10-diones in Hepatocellular C...

por Lin, Chia-Yang, Islam, Atikul, Su, Claire J., Tikhomirov, Alexander S., Shchekotikhin, Andrey E., Chuang, Show-Mei, Chueh, Pin Ju, Chen, Yao Li
Publicado 2019

Aminoalkylamides of Eremomycin Exhibit an Improved Antibacterial Activity

por Moiseenko, Elena I., Erdei, Réka, Grammatikova, Natalia E., Mirchink, Elena P., Isakova, Elena B., Pereverzeva, Eleonora R., Batta, Gyula, Shchekotikhin, Andrey E.
Publicado 2021

In Vitro Pharmacological Screening of Essential Oils from Baccharis parvidentata and Lippia origanoides Growing in Brazil

por Perera, Wilmer H., Scherbakov, Alexander M., Buravchenko, Galina I., Mikhaevich, Ekaterina I., Leitão, Suzana Guimarães, Cos, Paul, Shchekotikhin, Andrey E., Monzote, Lianet, Setzer, William N.
Publicado 2022

Bis(chloroacetamidino)-Derived Heteroarene-Fused Anthraquinones Bind to and Cause Proteasomal Degradation of tNOX, Leading to c-Flip Downregulation and Apoptosis in Oral Cancer Cel...

por Chang, Jeng Shiun, Chen, Chien-Yu, Tikhomirov, Alexander S., Islam, Atikul, Liang, Ru-Hao, Weng, Chia-Wei, Wu, Wei-Hou, Shchekotikhin, Andrey E., Chueh, Pin Ju
Publicado 2022

Design, Synthesis and In Vitro Investigation of Cabozantinib-Based PROTACs to Target c-Met Kinase

por Sachkova, Anastasia A., Andreeva, Daria V., Tikhomirov, Alexander S., Scherbakov, Alexander M., Salnikova, Diana I., Sorokin, Danila V., Bogdanov, Fedor B., Rysina, Yulia D., Shchekotikhin, Andrey E., Shchegravina, Ekaterina S., Fedorov, Alexey Yu.
Publicado 2022

Indoline-5-Sulfonamides: A Role of the Core in Inhibition of Cancer-Related Carbonic Anhydrases, Antiproliferative Activity and Circumventing of Multidrug Resistance

por Krymov, Stepan K., Scherbakov, Alexander M., Dezhenkova, Lyubov G., Salnikova, Diana I., Solov’eva, Svetlana E., Sorokin, Danila V., Vullo, Daniela, De Luca, Viviana, Capasso, Clemente, Supuran, Claudiu T., Shchekotikhin, Andrey E.
Publicado 2022

Eremomycin pyrrolidide: a novel semisynthetic glycopeptide with improved chemotherapeutic properties

por Olsufyeva, Evgenia N, Shchekotikhin, Andrey E, Bychkova, Elena N, Pereverzeva, Eleonora R, Treshalin, Ivan D, Mirchink, Elena P, Isakova, Elena B, Chernobrovkin, Mikhail G, Kozlov, Roman S, Dekhnich, Andrey V, Preobrazhenskaya, Maria N
Publicado 2018

Synthesis and Characterization of Novel 2-Acyl-3-trifluoromethylquinoxaline 1,4-Dioxides as Potential Antimicrobial Agents

por Buravchenko, Galina I., Maslov, Dmitry A., Alam, Md Shah, Grammatikova, Natalia E., Frolova, Svetlana G., Vatlin, Aleksey A., Tian, Xirong, Ivanov, Ivan V., Bekker, Olga B., Kryakvin, Maxim A., Dontsova, Olga A., Danilenko, Valery N., Zhang, Tianyu, Shchekotikhin, Andrey E.
Publicado 2022

Novel Derivatives of Quinoxaline-2-carboxylic Acid 1,4-Dioxides as Antimycobacterial Agents: Mechanistic Studies and Therapeutic Potential

por Frolova, Svetlana G., Vatlin, Aleksey A., Maslov, Dmitry A., Yusuf, Buhari, Buravchenko, Galina I., Bekker, Olga B., Klimina, Ksenia M., Smirnova, Svetlana V., Shnakhova, Lidia M., Malyants, Irina K., Lashkin, Arseniy I., Tian, Xirong, Alam, Md Shah, Zatonsky, George V., Zhang, Tianyu, Shchekotikhin, Andrey E., Danilenko, Valery N.
Publicado 2023