SARS Coronavirus Pathogenesis and Therapeutic Treatment Design

por Sheahan, Timothy P., Baric, Ralph S.
Publicado 2009

Local Health Departments’ Activities to Address Health Disparities and Inequities: Are We Moving in the Right Direction?

por Shah, Gulzar H., Sheahan, John P.
Publicado 2015

The continued epidemic threat of SARS-CoV-2 and implications for the future of global public health

por Sheahan, Timothy P, Frieman, Matthew B
Publicado 2020

Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis

por Leist, Sarah R., Jensen, Kara L., Baric, Ralph S., Sheahan, Timothy P.
Publicado 2019

Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication

por Adams, Lily E., Dinnon, Kenneth H., Hou, Yixuan J., Sheahan, Timothy P., Heise, Mark T., Baric, Ralph S.
Publicado 2021

A mechanism‐based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID‐19 treatment in humans

por Hanafin, Patrick O., Jermain, Brian, Hickey, Anthony J., Kabanov, Alexander V., Kashuba, Angela DM., Sheahan, Timothy P., Rao, Gauri G.
Publicado 2021

Transmission of viral pathogens in a social network of university students: the eX-FLU study

por Zivich, P.N., Eisenberg, M.C., Monto, A.S., Uzicanin, A., Baric, R. S., Sheahan, T. P., Rainey, J. J., Gao, H., Aiello, A. E.
Publicado 2020

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis

por Gralinski, Lisa E., Sheahan, Timothy P., Morrison, Thomas E., Menachery, Vineet D., Jensen, Kara, Leist, Sarah R., Whitmore, Alan, Heise, Mark T., Baric, Ralph S.
Publicado 2018

Multi-Modal Imaging with a Toolbox of Influenza A Reporter Viruses

por Tran, Vy, Poole, Daniel S., Jeffery, Justin J., Sheahan, Timothy P., Creech, Donald, Yevtodiyenko, Aleksey, Peat, Andrew J., Francis, Kevin P., You, Shihyun, Mehle, Andrew
Publicado 2015

β-d-N(4)-hydroxycytidine Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells

por Zhou, Shuntai, Hill, Collin S, Sarkar, Sanjay, Tse, Longping V, Woodburn, Blaide M D, Schinazi, Raymond F, Sheahan, Timothy P, Baric, Ralph S, Heise, Mark T, Swanstrom, Ronald
Publicado 2021

Fc-engineered antibody therapeutics with improved efficacy against COVID-19

por Yamin, Rachel, Jones, Andrew T, Hoffmann, Hans-Heinrich, Kao, Kevin S, Francis, Rebecca L, Sheahan, Timothy P, Baric, Ralph S, Rice, Charles M, Ravetch, Jeffrey V, Bournazos, Stylianos
Publicado 2021

Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase

por Brown, Ariane J., Won, John J., Graham, Rachel L., Dinnon, Kenneth H., Sims, Amy C., Feng, Joy Y., Cihlar, Tomas, Denison, Mark R., Baric, Ralph S., Sheahan, Timothy P.
Publicado 2019

COVID-19: from epidemiology to treatment

por Pericàs, J M, Hernandez-Meneses, M, Sheahan, T P, Quintana, E, Ambrosioni, J, Sandoval, E, Falces, C, Marcos, M A, Tuset, M, Vilella, A, Moreno, A, Miro, J M
Publicado 2020

Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach

por Uryu, Kunihiro, Soplop, Nadine, Sheahan, Timothy P., Catanese, Maria-Teresa, Huynh, Chuong, Pena, John, Boudreau, Nancy, Matei, Irina, Kenific, Candia, Hashimoto, Ayako, Hoshino, Ayuko, Rice, Charles M., Lyden, David
Publicado 2023

Expression of Paramyxovirus V Proteins Promotes Replication and Spread of Hepatitis C Virus in Cultures of Primary Human Fetal Liver Cells

por Andrus, Linda, Marukian, Svetlana, Jones, Christopher T, Catanese, Maria Teresa, Sheahan, Timothy P, Schoggins, John W, Barry, Walter T, Dustin, Lynn B, Trehan, Kartik, Ploss, Alexander, Bhatia, Sangeeta N, Rice, Charles M
Publicado 2011

Virus–Host Interactions Between Nonsecretors and Human Norovirus

por Lindesmith, Lisa C., Brewer-Jensen, Paul D., Mallory, Michael L., Jensen, Kara, Yount, Boyd L., Costantini, Veronica, Collins, Matthew H., Edwards, Caitlin E., Sheahan, Timothy P., Vinjé, Jan, Baric, Ralph S.
Publicado 2020

Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion

por Lindesmith, Lisa C., Mallory, Michael L., Debbink, Kari, Donaldson, Eric F., Brewer-Jensen, Paul D., Swann, Excel W., Sheahan, Timothy P., Graham, Rachel L., Beltramello, Martina, Corti, Davide, Lanzavecchia, Antonio, Baric, Ralph S.
Publicado 2018

Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate

por Iserman, Christiane, Roden, Christine, Boerneke, Mark, Sealfon, Rachel, McLaughlin, Grace, Jungreis, Irwin, Park, Chris, Boppana, Avinash, Fritch, Ethan, Hou, Yixuan J., Theesfeld, Chandra, Troyanskaya, Olga G, Baric, Ralph S., Sheahan, Timothy P., Weeks, Kevin, Gladfelter, Amy S.
Publicado 2020

Hepatoviruses promote very-long-chain fatty acid and sphingolipid synthesis for viral RNA replication and quasi-enveloped virus release

por Shiota, Tomoyuki, Li, Zhucui, Chen, Guan-Yuan, McKnight, Kevin L., Shirasaki, Takayoshi, Yonish, Bryan, Kim, Heyjeong, Fritch, Ethan J., Sheahan, Timothy P., Muramatsu, Masamichi, Kapustina, Maryna, Cameron, Craig E., Li, You, Zhang, Qibin, Lemon, Stanley M.
Publicado 2023

Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo

por Schäfer, Alexandra, Muecksch, Frauke, Lorenzi, Julio C. C., Leist, Sarah R., Cipolla, Melissa, Bournazos, Stylianos, Schmidt, Fabian, Gazumyan, Anna, Baric, Ralph S., Robbiani, Davide F., Hatziioannou, Theodora, Ravetch, Jeffrey V., Bieniasz, Paul D., Nussenzweig, Michel C., Sheahan, Timothy P.
Publicado 2020